Determine the necessary mass, volume, or concentration for preparing a solution.
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SKU | Size | Availability | Price | Qty |
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A136993-1g | 1g | In stock | $16.90 | |
A136993-5g | 5g | In stock | $63.90 | |
A136993-25g | 25g | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $189.90 |
Synonyms | ALENDRONIC ACID|alendronate|66376-36-1|Fosamax|(4-amino-1-hydroxy-1-phosphonobutyl)phosphonic acid|Acido alendronico|Acide alendronique|Acidum alendronicum|Arendal|(4-Amino-1-hydroxybutane-1,1-diyl)diphosphonic acid|(4-Amino-1-hydroxybutylidene)bisphospho |
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Specifications & Purity | Moligand™, ≥98% |
Shipped In | Normal |
Grade | Moligand™ |
Action Type | INHIBITOR |
Mechanism of action | Inhibitor of farnesyl diphosphate synthase |
Product Description | Alendronate acid is an inhibitor of FDPS. It is a bisphosphonate that inhibits osteoclast-mediated bone resorption. Unlike pyrophosphate, the endogenous regulator of bone turnover to which it is chemically related, alendronate specifically inhibits osteoclastic osteoclastic bone resorption, having no effect on mineralization of bone newly formed by osteoblasts. |
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Pubchem Sid | 488179658 |
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Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/488179658 |
IUPAC Name | (4-amino-1-hydroxy-1-phosphonobutyl)phosphonic acid |
INCHI | InChI=1S/C4H13NO7P2/c5-3-1-2-4(6,13(7,8)9)14(10,11)12/h6H,1-3,5H2,(H2,7,8,9)(H2,10,11,12) |
InChi Key | OGSPWJRAVKPPFI-UHFFFAOYSA-N |
Canonical SMILES | C(CC(O)(P(=O)(O)O)P(=O)(O)O)CN |
Isomeric SMILES | C(CC(O)(P(=O)(O)O)P(=O)(O)O)CN |
RTECS | SZ6521833 |
Alternate CAS | 121268-17-5 |
PubChem CID | 2088 |
Molecular Weight | 249.1 |
Reaxy-Rn | 2275403 |
DrugBank Ligand | DB00630 |
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Wikipedia | Alendronic_acid |
CAS Registry No. | 66376-36-1 |
PubChem CID | 2088 |
ChEMBL Ligand | CHEMBL870 |
RCSB PDB Ligand | 212 |
PEP | alendronate |
DrugCentral Ligand | 112 |
PubChem SID | 488179658 |
Enter Lot Number to search for COA:
To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section
Lot Number | Certificate Type | Date | Item |
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H2205713 | Certificate of Analysis | May 09, 2024 | A136993 |
H2205712 | Certificate of Analysis | May 07, 2024 | A136993 |
A2211264 | Certificate of Analysis | Oct 16, 2023 | A136993 |
I2311168 | Certificate of Analysis | Jul 19, 2023 | A136993 |
I2311150 | Certificate of Analysis | Jul 19, 2023 | A136993 |
I2311149 | Certificate of Analysis | Jul 19, 2023 | A136993 |
G2320303 | Certificate of Analysis | Jun 05, 2023 | A136993 |
G2320304 | Certificate of Analysis | Jun 05, 2023 | A136993 |
G2320305 | Certificate of Analysis | Jun 05, 2023 | A136993 |
G2320307 | Certificate of Analysis | Jun 05, 2023 | A136993 |
G2320308 | Certificate of Analysis | Jun 05, 2023 | A136993 |
J2010113 | Certificate of Analysis | Aug 11, 2022 | A136993 |
G2220411 | Certificate of Analysis | Jul 25, 2022 | A136993 |
E2315393 | Certificate of Analysis | Jul 25, 2022 | A136993 |
H2205714 | Certificate of Analysis | Jul 25, 2022 | A136993 |
D2310190 | Certificate of Analysis | Jul 25, 2022 | A136993 |
E2315384 | Certificate of Analysis | Jul 25, 2022 | A136993 |
A2211273 | Certificate of Analysis | Jan 05, 2022 | A136993 |
A2211272 | Certificate of Analysis | Jan 05, 2022 | A136993 |
Melt Point(°C) | 235°C(dec.)(lit.) |
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Pictogram(s) | GHS08, GHS05, GHS07 |
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Signal | Danger |
Hazard Statements | H315:Causes skin irritation H319:Causes serious eye irritation H314:Causes severe skin burns and eye damage H302:Harmful if swallowed H318:Causes serious eye damage H290:May be corrosive to metals H361:Suspected of damaging fertility or the unborn child H371:May cause damage to organs |
Precautionary Statements | P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P260:Do not breathe dust/fume/gas/mist/vapors/spray. P270:Do not eat, drink or smoke when using this product. P301+P330+P331:IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P363:Wash contaminated clothing before reuse. P362+P364:Take off contaminated clothing and wash it before reuse. P330:Rinse mouth. P234:Keep only in original container. P390:Absorb spillage to prevent material damage. P406:Store in corrosive resistant/... container with a resistant inner liner. P203:Obtain, read and follow all safety instructions before use. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P301+P317:IF SWALLOWED: Get medical help. P305+P354+P338:IF IN EYES: Immediately rinse with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing. P318:if exposed or concerned, get medical advice. P317:Get emergency medical help. P337+P317:If eye irritation persists: Get medical help. P308+P316:IF exposed or concerned: Get emergency medical help immediately. P332+P317:If skin irritation occurs: Get medical help. P302+P361+P354:IF ON SKIN: Take off Immediately all contaminated clothing. Immediately rinse with water for several minutes. P316:Get emergency medical help immediately. |
RTECS | SZ6521833 |
Reaxy-Rn | 2275403 |
Merck Index | 229 |