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Alizarin - Analytical Reagent, high purity , CAS No.72-48-0

9 Citations

CAS#: 72-48-0
Formula: C₁₄H₈O₄
Molecular Weight: 240.21
Beilstein Registry Number: 1914037
EC Number: 200-782-5
MDL number: MFCD00001201
PubChem CID: 6293
PubChem SID: 488180042

Item Number

A110680

Grouped product items
SKU	Size	Availability	Price
A110680-25g	25g	In stock	$34.90
A110680-100g	100g	In stock	$85.90
A110680-500g	500g	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$309.90

Basic Description

Synonyms	Alizarin \| 72-48-0 \| 1,2-dihydroxyanthracene-9,10-dione \| Alizarin Red \| Mordant Red 11 \| 1,2-Dihydroxyanthraquinone \| Alizarin B \| Turkey Red \| 1,2-Dihydroxy-9,10-anthracenedione \| ALIZARINE \| 1,2-Anthraquinonediol \| Alizarina \| Alizarine Red \| Eljon Madder \| Alizarine B \| Alizarine
Specifications & Purity	AR
Biochemical and Physiological Mechanisms	Alizarin (1, 2-dihydroxyanthraquinone) is an anthraquinone dye and acts as a main chromophore of madder dye. It is used as a dye in the production of lake pigments. Alizarin is a key constituent in extracts of roots of various members of Rubiaceae, Morind
Storage Temp	Store at 2-8°C,Desiccated
Shipped In	Wet ice
Grade	AR
Product Description	Alizarin has been used as a biological stain to dye cotton fabrics and is used as standard in UV-visible spectrophotometer.

Associated Targets(Human)

CYP1B1 Tchem Cytochrome P450 1B1 (1 Activities)

Discover Target: CYP1B1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

MAOA Tclin Monoamine oxidase A (11911 Activities)

Discover Target: MAOA

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

MAOB Tclin Monoamine oxidase B (8835 Activities)

Discover Target: MAOB

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CYP1B1 Tchem Cytochrome P450 1B1 (1148 Activities)

Discover Target: CYP1B1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

PLK1 Tchem Serine/threonine-protein kinase PLK1 (28605 Activities)

Discover Target: PLK1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ALOX15B Tchem Arachidonate 15-lipoxygenase, type II (7244 Activities)

Discover Target: ALOX15B

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ALDH1A1 Tchem Aldehyde dehydrogenase 1A1 (77053 Activities)

Discover Target: ALDH1A1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ALOX12 Tchem Arachidonate 12-lipoxygenase (3262 Activities)

Discover Target: ALOX12

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ALOX15 Tchem Arachidonate 15-lipoxygenase (7108 Activities)

Discover Target: ALOX15

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

UGT1A4 Tbio UDP-glucuronosyltransferase 1A4 (288 Activities)

Discover Target: UGT1A4

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

PIN1 Tchem Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (36611 Activities)

Discover Target: PIN1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CYP3A4 Tclin Cytochrome P450 3A4 (53859 Activities)

Discover Target: CYP3A4

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

A498 (42825 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ACHN (49357 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CAKI-1 (44928 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CCRF-CEM (65223 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

COLO 205 (50209 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

DLD-1 (17511 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

DMS-273 (14108 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

HT-29 (80576 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

K562 (73714 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

KM12 (47707 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

M14 (47487 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

MOLT-4 (49676 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

OVCAR-3 (48710 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

OVCAR-4 (44535 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

OVCAR-5 (45555 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

OVCAR-8 (47708 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Raji (5516 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

RPMI-8226 (44974 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

RXF 393 (41971 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SF-295 (48000 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SK-MEL-2 (46422 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SK-MEL-28 (48833 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SN12C (47755 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SNB-19 (46794 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SNB-78 (14240 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

TK-10 (45540 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

U-251 (51189 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

UACC-257 (46019 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

UACC-62 (47335 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

UO-31 (46270 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

XF498 (12972 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

786-0 (47912 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

A549 (127892 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

EKVX (44102 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

NCI-H1299 (3248 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

NCI-H322M (45589 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

HCC 2998 (41480 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

HCT-116 (91556 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

HOP-92 (41141 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Associated Targets(non-human)

pol Human immunodeficiency virus type 1 reverse transcriptase (18245 Activities)

Discover Target: pol

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Ttr Transthyretin (14 Activities)

Discover Target: Ttr

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mapk1 MAP kinase ERK2 (650 Activities)

Discover Target: Mapk1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Pklr Pyruvate kinase isozymes R/L (113 Activities)

Discover Target: Pklr

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Brugia malayi (1377 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

P388 (20296 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

L929 (3802 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

GCN5 Histone acetyltransferase GCN5 (89 Activities)

Discover Target: GCN5

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Dyrk1a Dual specificity tyrosine-phosphorylation-regulated kinase 1A (1629 Activities)

Discover Target: Dyrk1a

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Luciferin 4-monooxygenase (66902 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

gag-pol Gag-Pol polyprotein (8 Activities)

Discover Target: gag-pol

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Erwinia amylovora (182 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

rmtA RmtA (95 Activities)

Discover Target: rmtA

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mapt Microtubule-associated protein tau (6 Activities)

Discover Target: Mapt

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Impa1 Inositol monophosphatase 1 (16203 Activities)

Discover Target: Impa1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Phosphoglycerate kinase, glycosomal (2184 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ESR1 Estrogen receptor (4 Activities)

Discover Target: ESR1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

vpr Aberrant vpr protein (14595 Activities)

Discover Target: vpr

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SARS-CoV-2 (38078 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Names and Identifiers

Pubchem Sid	488180042
Pubchem Sid Url	https://pubchem.ncbi.nlm.nih.gov/substance/488180042
IUPAC Name	1,2-dihydroxyanthracene-9,10-dione
INCHI	InChI=1S/C14H8O4/c15-10-6-5-9-11(14(10)18)13(17)8-4-2-1-3-7(8)12(9)16/h1-6,15,18H
InChi Key	RGCKGOZRHPZPFP-UHFFFAOYSA-N
Canonical SMILES	C1=CC=C2C(=C1)C(=O)C3=C(C2=O)C(=C(C=C3)O)O
Isomeric SMILES	C1=CC=C2C(=C1)C(=O)C3=C(C2=O)C(=C(C=C3)O)O
WGK Germany	3
RTECS	CB6580000
PubChem CID	6293
Molecular Weight	240.21
Beilstein	1914037
Reaxy-Rn	1914037

Certificates

Certificate of Analysis(COA)

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4 results found

Lot Number	Certificate Type	Date	Item
F2008034	Certificate of Analysis	Apr 02, 2024	A110680
B2325286	Certificate of Analysis	Mar 08, 2023	A110680
B2325287	Certificate of Analysis	Mar 03, 2023	A110680
A2417116	Certificate of Analysis	Oct 25, 2021	A110680

Chemical and Physical Properties

Solubility	Soluble in hexane and chloroform. Slightly soluble in water.
Boil Point(°C)	430°C
Melt Point(°C)	290°C

Safety and Hazards(GHS)

Pictogram(s)	GHS08, GHS07
Signal	Warning
Hazard Statements	H341:Suspected of causing genetic defects H315+H320:Cause skin and eye irritation
Precautionary Statements	P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P201:Obtain special instructions before use. P308+P313:IF exposed or concerned: Get medical advice/attention. P337+P313:IF eye irritation persists: Get medical advice/attention. P362+P364:Take off contaminated clothing and wash it before reuse. P332+P313:IF SKIN irritation occurs: Get medical advice/attention. P202:Do not handle until all safety precautions have been read and understood.
WGK Germany	3
RTECS	CB6580000
Reaxy-Rn	1914037
Merck Index	251

Citations of This Product

1. Jin-jing Hu, Zeng-hui Sun, Zi-wei Wu, Chao Tu, Li Cui, Yao-jun Tan. (2024) One-Step Preparation of Ph-Sensitive and Antibacterial Calcium Alginate Fibers: In Situ Reduction Method and Original Solution Dyeing. MACROMOLECULAR CHEMISTRY AND PHYSICS, 225 (4): (2300255). [PMID:]
2. Jun Jiang, Baixiu Zhao, Jianpeng Xiao, Liang Shi, Wei Shang, Ye Shu, Zhiming Zhao, Junyi Shen, Jingjuan Xu, Hui Cai. (2023) Exploring the boost of steaming with wine on Ligustri Lucidi Fructus in treating postmenopausal osteoporosis based on superior “multi-component structure” and iron/bone metabolism coregulation. PHYTOMEDICINE, (155275). [PMID:38142661]
3. Meimei Yu, Yuanyou Peng, Yu Wang, Facai Guo, Fen Ran. (2023) All-in-one membrane micro-supercapacitors for implantable devices. JOURNAL OF MEMBRANE SCIENCE, 687 (24): (122084). [PMID:20864032]
4. Wanmei Lin, Yifan Zhang, Jihong Huang, Zhonghong Li. (2023) pH-responsive double-layer film based on chitosan/curcumin-β-cyclodextrin complex/cinnamaldehyde and zein/alizarin for pork freshness monitoring and maintaining. FOOD RESEARCH INTERNATIONAL, 173 (9): (113460). [PMID:37803785]
5. Shaochi Wang, Ting Du, Ying Zhu, Sijie Liu, Junqi Huangmin, Liang Zhang, Daize Shi, Minghui Zhang, Jing Sun, Daohong Zhang, Jianlong Wang. (2024) Natural needle microstructure-based immunochromatographic assay for sensitively detecting streptomycin in food products. FOOD CHEMISTRY, 434 (29): (137413). [PMID:37696155]
6. Yukun Wang, Zhiyu Jin, Zijun Zhang, Changkai Zhou, Zhe Sun, Feng Yan. (2023) pH-Responsive Polymer Films Based on Click Polymerization for Food Freshness Monitoring: Non-Toxic, Non-Leaking, and Antibacterial. ACS Applied Materials & Interfaces, 15 (28): (33998–34007). [PMID:37403437]
7. Weiya Zeng, Yuan Fang, Suifen Mo, Caihong Shen, Huiling Yang, Guihua Luo, Luhua Xiao, Ruoting Zhan, Ping Yan. (2023) The Underling Mechanisms Exploration of Rubia cordifolia L. Extract Against Rheumatoid Arthritis by Integrating Network Pharmacology and Metabolomics. Drug Design Development and Therapy, [PMID:36818604]
8. Binjie Wang, Tianyi Chen, Anli Wang, Jiakai Fang, Jiye Wang, Weixuan Yao, Yuanzhao Wu. (2021) Anisodamine affects the pigmentation, mineral density, craniofacial area, and eye development in zebrafish embryos. JOURNAL OF APPLIED TOXICOLOGY, 42 (6): (1067-1077). [PMID:34967033]
9. Yu Wang, Xing-yi Huang, Joshua Aheto, Yi Ren, Xiaorui Zhang, Li Wang. (2021) Novel colorimetric sensor array for Chinese rice wine evaluation based on color reactions of flavor compounds. JOURNAL OF FOOD PROCESS ENGINEERING, 44 (12): (e13889). [PMID:]

References

1. Jin-jing Hu, Zeng-hui Sun, Zi-wei Wu, Chao Tu, Li Cui, Yao-jun Tan. (2024) One-Step Preparation of Ph-Sensitive and Antibacterial Calcium Alginate Fibers: In Situ Reduction Method and Original Solution Dyeing. MACROMOLECULAR CHEMISTRY AND PHYSICS, 225 (4): (2300255). [PMID:]
2. Jun Jiang, Baixiu Zhao, Jianpeng Xiao, Liang Shi, Wei Shang, Ye Shu, Zhiming Zhao, Junyi Shen, Jingjuan Xu, Hui Cai. (2023) Exploring the boost of steaming with wine on Ligustri Lucidi Fructus in treating postmenopausal osteoporosis based on superior “multi-component structure” and iron/bone metabolism coregulation. PHYTOMEDICINE, (155275). [PMID:38142661]
3. Meimei Yu, Yuanyou Peng, Yu Wang, Facai Guo, Fen Ran. (2023) All-in-one membrane micro-supercapacitors for implantable devices. JOURNAL OF MEMBRANE SCIENCE, 687 (24): (122084). [PMID:20864032]
4. Wanmei Lin, Yifan Zhang, Jihong Huang, Zhonghong Li. (2023) pH-responsive double-layer film based on chitosan/curcumin-β-cyclodextrin complex/cinnamaldehyde and zein/alizarin for pork freshness monitoring and maintaining. FOOD RESEARCH INTERNATIONAL, 173 (9): (113460). [PMID:37803785]
5. Shaochi Wang, Ting Du, Ying Zhu, Sijie Liu, Junqi Huangmin, Liang Zhang, Daize Shi, Minghui Zhang, Jing Sun, Daohong Zhang, Jianlong Wang. (2024) Natural needle microstructure-based immunochromatographic assay for sensitively detecting streptomycin in food products. FOOD CHEMISTRY, 434 (29): (137413). [PMID:37696155]
6. Yukun Wang, Zhiyu Jin, Zijun Zhang, Changkai Zhou, Zhe Sun, Feng Yan. (2023) pH-Responsive Polymer Films Based on Click Polymerization for Food Freshness Monitoring: Non-Toxic, Non-Leaking, and Antibacterial. ACS Applied Materials & Interfaces, 15 (28): (33998–34007). [PMID:37403437]
7. Weiya Zeng, Yuan Fang, Suifen Mo, Caihong Shen, Huiling Yang, Guihua Luo, Luhua Xiao, Ruoting Zhan, Ping Yan. (2023) The Underling Mechanisms Exploration of Rubia cordifolia L. Extract Against Rheumatoid Arthritis by Integrating Network Pharmacology and Metabolomics. Drug Design Development and Therapy, [PMID:36818604]
8. Binjie Wang, Tianyi Chen, Anli Wang, Jiakai Fang, Jiye Wang, Weixuan Yao, Yuanzhao Wu. (2021) Anisodamine affects the pigmentation, mineral density, craniofacial area, and eye development in zebrafish embryos. JOURNAL OF APPLIED TOXICOLOGY, 42 (6): (1067-1077). [PMID:34967033]
9. Yu Wang, Xing-yi Huang, Joshua Aheto, Yi Ren, Xiaorui Zhang, Li Wang. (2021) Novel colorimetric sensor array for Chinese rice wine evaluation based on color reactions of flavor compounds. JOURNAL OF FOOD PROCESS ENGINEERING, 44 (12): (e13889). [PMID:]

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