Allicin - 10mM in DMSO, high purity , CAS No.539-86-6

  • 10mM in DMSO
Item Number
A424615
Grouped product items
SKUSizeAvailabilityPrice Qty
A424615-1ml
1ml
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$69.90

Antibacterial and antifungal agent

Basic Description

SynonymsAllicin | 539-86-6 | Diallyl thiosulfinate | S-allyl prop-2-ene-1-sulfinothioate | Diallyldisulfid-S-oxid | Thio-2-propene-1-sulfinic acid S-allyl ester | Allylthiosulphinic acid allyl ester | DADSO | S-Allyl acrylo-1-sulphinothioate | 2-Propene-1-sulfinothioic acid, S-2-p
Specifications & Purity10mM in DMSO
Biochemical and Physiological MechanismsAntibacterial against Gram-negative and Gram-positive bacteria, including multidrug-resistant enterotoxicogenic strains of E.coli . Displays antifungal and antiparasitic effects and enhances the production of IFN-γ, TNF, IL-12p70 and NO in vivo .
Storage TempStore at -80°C
Shipped InIce chest + Ice pads
Product Description

The main component is diallyl disulfide+diallyl trisulfide+trithiodipropene

Associated Targets(Human)

TRPA1 Tclin Transient receptor potential cation channel subfamily A member 1 (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
TERT Tchem Telomerase reverse transcriptase (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
SLC25A21 Tchem Mitochondrial 2-oxodicarboxylate carrier (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
HMGCR Tclin HMG-CoA reductase (2475 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
TRPV1 Tclin Vanilloid receptor (8273 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CTSB Tchem Cathepsin B (3822 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
TERT Tchem Telomerase reverse transcriptase (2428 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Daudi (625 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HL-60 (67320 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HT-29 (80576 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MOLT-4 (49676 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
NCI-N87 (850 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
U-937 (7138 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Jurkat (10389 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HeLa (62764 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SK-N-AS (237 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SCNN1A Tclin Amiloride-sensitive sodium channel, ENaC (10 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SK-N-FI (180 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SK-N-BE(2)-M17 (195 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

CTSL Cathepsin L (58 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Pseudomonas aeruginosa (123386 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Enterobacter cloacae (7976 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Klebsiella pneumoniae (43867 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Staphylococcus aureus (210822 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Acinetobacter baumannii (41033 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Enterococcus faecium (13803 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Aspergillus fumigatus (16427 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Trypanosoma brucei brucei (13300 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Plasmodium falciparum (966862 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Plasmodium berghei (192651 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Plasmodium yoelii (6656 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Meloidogyne incognita (862 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Rattus norvegicus (775804 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
rhodesain Rhodesain (1463 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Trpa1 Transient receptor potential cation channel subfamily A member 1 (1003 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

IUPAC Name 3-prop-2-enylsulfinylsulfanylprop-1-ene
INCHI InChI=1S/C6H10OS2/c1-3-5-8-9(7)6-4-2/h3-4H,1-2,5-6H2
InChi Key JDLKFOPOAOFWQN-UHFFFAOYSA-N
Canonical SMILES C=CCSS(=O)CC=C
Isomeric SMILES C=CCSS(=O)CC=C
PubChem CID 65036
Molecular Weight 162.27

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Chemical and Physical Properties

Refractive Indexn20/D 1.409(lit.)
Flash Point(°C)48.88ºC
Boil Point(°C)136-138 °C(lit.)
Melt Point(°C)-70 °C

Safety and Hazards(GHS)

Pictogram(s) GHS07
Signal Warning
Hazard Statements

H315:Causes skin irritation

H319:Causes serious eye irritation

H335:May cause respiratory irritation

Precautionary Statements

P261:Avoid breathing dust/fume/gas/mist/vapors/spray.

P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352:IF ON SKIN: wash with plenty of water.

P321:Specific treatment (see ... on this label).

P405:Store locked up.

P501:Dispose of contents/container to ...

P264:Wash hands [and …] thoroughly after handling.

P271:Use only outdoors or in a well-ventilated area.

P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing.

P403+P233:Store in a well-ventilated place. Keep container tightly closed.

P362+P364:Take off contaminated clothing and wash it before reuse.

P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes.

P337+P317:If eye irritation persists: Get medical help.

P332+P317:If skin irritation occurs: Get medical help.

P319:Get medical help if you feel unwell.

Related Documents

Citations of This Product

1. Weiqing Lan, Bingjie Zhang, Jintao Du, Shengyun Zhu, Xiao Xu, Jing Xie.  (2023)  Synergistic Effect of Combined Treatment with Allicin and Antioxidant of Bamboo Leaves and Preservation of Bullfrogs (Lithobates catesbeiana) during Refrigeration Storage.  Foods,  12  (18): (3467).  [PMID:37761176] [10.3390/foods12183467]
2. Chi Zhang, Man Fang, Yuanbo Gao, Yunchao Li, Louzhen Fan, Xiaohong Li.  (2023)  Valence-Engineered Oxidase-Mimicking Nanozyme with Specificity for Aromatic Amine Oxidation and Identification.  ANALYTICAL CHEMISTRY,  95  (28): (10713–10720).  [PMID:37402320] [10.1021/acs.analchem.3c01488]
3. Jing Nie, Rui Weng, Chunlin Li, Xiuhua Liu, Fang Wang, Karyne M. Rogers, Yongzhong Qian, Yongzhi Zhang, Yuwei Yuan.  (2022)  Chemometric origin classification of Chinese garlic using sulfur-containing compounds, assisted by stable isotopes and bioelements.  FOOD CHEMISTRY,  394  (133557).  [PMID:35759834] [10.1016/j.foodchem.2022.133557]
4. Fan Zhi-xia, Zhang Jing, Wang Xin, Miao Guo-ying.  (2023)  Convergent Fabrication of Allicin Loaded Polymeric Nanoparticles for Treatment of In Vitro Squamous Carcinoma Cells and Systemic Toxicity.  JOURNAL OF CLUSTER SCIENCE,  34  (2): (761-771).  [PMID:] [10.1007/s10876-022-02246-1]

References

1. Weiqing Lan, Bingjie Zhang, Jintao Du, Shengyun Zhu, Xiao Xu, Jing Xie.  (2023)  Synergistic Effect of Combined Treatment with Allicin and Antioxidant of Bamboo Leaves and Preservation of Bullfrogs (Lithobates catesbeiana) during Refrigeration Storage.  Foods,  12  (18): (3467).  [PMID:37761176] [10.3390/foods12183467]
2. Chi Zhang, Man Fang, Yuanbo Gao, Yunchao Li, Louzhen Fan, Xiaohong Li.  (2023)  Valence-Engineered Oxidase-Mimicking Nanozyme with Specificity for Aromatic Amine Oxidation and Identification.  ANALYTICAL CHEMISTRY,  95  (28): (10713–10720).  [PMID:37402320] [10.1021/acs.analchem.3c01488]
3. Jing Nie, Rui Weng, Chunlin Li, Xiuhua Liu, Fang Wang, Karyne M. Rogers, Yongzhong Qian, Yongzhi Zhang, Yuwei Yuan.  (2022)  Chemometric origin classification of Chinese garlic using sulfur-containing compounds, assisted by stable isotopes and bioelements.  FOOD CHEMISTRY,  394  (133557).  [PMID:35759834] [10.1016/j.foodchem.2022.133557]
4. Fan Zhi-xia, Zhang Jing, Wang Xin, Miao Guo-ying.  (2023)  Convergent Fabrication of Allicin Loaded Polymeric Nanoparticles for Treatment of In Vitro Squamous Carcinoma Cells and Systemic Toxicity.  JOURNAL OF CLUSTER SCIENCE,  34  (2): (761-771).  [PMID:] [10.1007/s10876-022-02246-1]

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