Aloe-emodin - 95%, high purity , CAS No.481-72-1

  • ≥95%
Item Number
A111278
Grouped product items
SKUSizeAvailabilityPrice Qty
A111278-25mg
25mg
In stock
$43.90
A111278-100mg
100mg
In stock
$133.90
A111278-250mg
250mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$161.90
A111278-500mg
500mg
In stock
$293.90
A111278-1g
1g
In stock
$532.90
A111278-5g
5g
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,394.90
A111278-25g
25g
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$10,773.90

Apoptotic and anticancer agent

Basic Description

Synonyms9,10-Anthracenedione, 1,8-dihydroxy-3-(hydroxymethyl)- | Aloeemodin | Aloe-emodin | Aloe-emodin, analytical standard | Q-100526 | MLS000697563 | s2259 | CCG-208456 | SR-01000765772-3 | 3-(Hydroxymethyl)chrysazin | 9,10-Dihydro-4,5-dihydroxy-9,10-dioxo-2-h
Specifications & Purity≥95%
Biochemical and Physiological MechanismsLaxative/cathartic compound; increases the contraction of intestinal smooth muscle by releasing endogenous acetylcholine. Anti-tumor activity is associated with an increased production of reactive oxygen species (ROS) that, in turn, reduces the mitochondr
Storage TempStore at 2-8°C
Shipped InWet ice
NoteWherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Associated Targets(Human)

EGFR Tclin Epidermal growth factor receptor erbB1 (33727 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ESR1 Tclin Estrogen receptor alpha (17718 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
AR Tclin Androgen Receptor (11781 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MAOA Tclin Monoamine oxidase A (11911 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ACHE Tclin Acetylcholinesterase (18204 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MAOB Tclin Monoamine oxidase B (8835 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
XDH Tclin Xanthine dehydrogenase (1038 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
P2RY12 Tclin Purinergic receptor P2Y12 (2369 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ELANE Tclin Leukocyte elastase (8173 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CTSG Tchem Cathepsin G (2304 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
EPHX2 Tchem Epoxide hydratase (3844 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GLP1R Tclin Glucagon-like peptide 1 receptor (111429 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ALPG Tchem Alkaline phosphatase placental-like (1197 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PIN1 Tchem Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (36611 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
A498 (42825 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ACHN (49357 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CAKI-1 (44928 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CCRF-CEM (65223 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
COLO 205 (50209 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
DLD-1 (17511 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
DMS-273 (14108 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HL-60 (67320 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HT-29 (80576 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
KM12 (47707 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
M14 (47487 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MCF7 (126967 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MOLT-4 (49676 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
OVCAR-3 (48710 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
OVCAR-4 (44535 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
OVCAR-5 (45555 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PC-3 (62116 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
RPMI-8226 (44974 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
RXF 393 (41971 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
RXF 631 (11415 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SF-295 (48000 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SK-MEL-2 (46422 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SK-MEL-28 (48833 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SK-MEL-5 (47095 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SK-OV-3 (52876 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SN12C (47755 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SNB-19 (46794 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SNB-78 (14240 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
TK-10 (45540 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
U-251 (51189 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
UACC-257 (46019 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
XF498 (12972 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
A549 (127892 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
A-431 (6446 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
NCI-H322M (45589 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HCC 2998 (41480 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

Alpha-chymotrypsin (819 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Ttr Transthyretin (14 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Ppard Peroxisome proliferator-activated receptor delta (358 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CELA2A Elastase 2A (403 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Hdac6 Histone deacetylase 6 (222 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Iap Intestinal alkaline phosphatase (419 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Pseudomonas aeruginosa (123386 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Klebsiella pneumoniae (43867 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Staphylococcus aureus (210822 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Acinetobacter baumannii (41033 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Escherichia coli (133304 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Streptococcus mutans (2687 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Phytophthora infestans (820 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Enterococcus faecalis (29875 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Plasmodium falciparum (966862 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Fusarium oxysporum (3998 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mus musculus (284745 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Hepatitis B virus (7925 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Hepatitis C virus (23859 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PC-12 (7051 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Man1 Alpha-mannosidase (188 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
B16-F10 (4610 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
FUCA1 Alpha-L-fucosidase 1 (358 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Txnrd2 Thioredoxin reductase 2, mitochondrial (18 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
rep Replicase polyprotein 1ab (378 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Aldh1a7 Aldehyde dehydrogenase, cytosolic 1 (5 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Txnrd1 Thioredoxin reductase 1, cytoplasmic (45279 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
BCHE Cholinesterase (8742 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Erwinia amylovora (182 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Nfe2l2 Nuclear factor erythroid 2-related factor 2 (214 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ESR1 Estrogen receptor (4 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Fusarium graminearum (1554 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SARS-CoV-2 (38078 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

Pubchem Sid488181089
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/488181089
IUPAC Name 1,8-dihydroxy-3-(hydroxymethyl)anthracene-9,10-dione
INCHI InChI=1S/C15H10O5/c16-6-7-4-9-13(11(18)5-7)15(20)12-8(14(9)19)2-1-3-10(12)17/h1-5,16-18H,6H2
InChi Key YDQWDHRMZQUTBA-UHFFFAOYSA-N
Canonical SMILES C1=CC2=C(C(=C1)O)C(=O)C3=C(C2=O)C=C(C=C3O)CO
Isomeric SMILES C1=CC2=C(C(=C1)O)C(=O)C3=C(C2=O)C=C(C=C3O)CO
WGK Germany 3
RTECS CB6712200
PubChem CID 10207
Molecular Weight 270.24
Beilstein 2059062

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Find and download the COA for your product by matching the lot number on the packaging.

17 results found

Lot NumberCertificate TypeDateItem
K2414100Certificate of AnalysisNov 19, 2024 A111278
D2424088Certificate of AnalysisMar 09, 2024 A111278
D2424089Certificate of AnalysisMar 09, 2024 A111278
B2420036Certificate of AnalysisFeb 27, 2024 A111278
H2401015Certificate of AnalysisFeb 27, 2024 A111278
J2211676Certificate of AnalysisMay 25, 2023 A111278
J2211659Certificate of AnalysisMay 25, 2023 A111278
J2211616Certificate of AnalysisMay 25, 2023 A111278
J2211620Certificate of AnalysisMay 25, 2023 A111278
J2211634Certificate of AnalysisMay 25, 2023 A111278
E1921029Certificate of AnalysisMar 08, 2023 A111278
B2325258Certificate of AnalysisMar 02, 2023 A111278
B2325259Certificate of AnalysisMar 02, 2023 A111278
K1826043Certificate of AnalysisSep 16, 2022 A111278
J1819038Certificate of AnalysisAug 10, 2022 A111278
K2110548Certificate of AnalysisNov 17, 2021 A111278
B2325257Certificate of AnalysisNov 17, 2021 A111278

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Chemical and Physical Properties

SensitivityHeat sensitive.
Melt Point(°C)223-224°C

Safety and Hazards(GHS)

Pictogram(s) GHS07
Signal Warning
Hazard Statements

H315:Causes skin irritation

H319:Causes serious eye irritation

H335:May cause respiratory irritation

Precautionary Statements

P261:Avoid breathing dust/fume/gas/mist/vapors/spray.

P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352:IF ON SKIN: wash with plenty of water.

P321:Specific treatment (see ... on this label).

P405:Store locked up.

P501:Dispose of contents/container to ...

P264:Wash hands [and …] thoroughly after handling.

P271:Use only outdoors or in a well-ventilated area.

P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing.

P403+P233:Store in a well-ventilated place. Keep container tightly closed.

P362+P364:Take off contaminated clothing and wash it before reuse.

P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes.

P337+P317:If eye irritation persists: Get medical help.

P332+P317:If skin irritation occurs: Get medical help.

P319:Get medical help if you feel unwell.

WGK Germany 3
RTECS CB6712200
Merck Index 306

Related Documents

Citations of This Product

1. Wenbin Chen, Airi N. Kato, Lijun Dai, Paul S. Clegg, Tao Li.  (2023)  Continuous Emulsion Channels Achieved by Controlling the Aqueous–Oil Interface Solely with Rough Colloids.  ADVANCED FUNCTIONAL MATERIALS,  34  (6): (2308608).  [PMID:9647693] [10.1002/adfm.202308608]
2. Mengsi Zhang, Lu Wang, Hao Jin, Nan Zhao, Yi Liu, Shijie Lan, Shuwei Liu, Hao Zhang.  (2023)  Employing single valency polyphenol to prepare metal-phenolic network antitumor reagents through FeOOH assistance.  JOURNAL OF CONTROLLED RELEASE,  358  (612).  [PMID:37196899] [10.1016/j.jconrel.2023.05.020]
3. Huijie Gao, Yan Ren, Chao Liu.  (2022)  Aloe-Emodin Suppresses Oxidative Stress and Inflammation via a PI3K-Dependent Mechanism in a Murine Model of Sepsis.  Evidence-based Complementary and Alternative Medicine,  2022  (9697887).  [PMID:35978995] [10.1155/2022/9697887]
4. Yuanyuan Song, Ziqi Wang, Yijing Long, Yang Mao, Feng Jiang, Yuanyuan Lu.  (2022)  2-Alkyl-anthraquinones inhibit Candida albicans biofilm via inhibiting the formation of matrix and hyphae.  RESEARCH IN MICROBIOLOGY,  173  (103955).  [PMID:35550403] [10.1016/j.resmic.2022.103955]
5. Rui Wang, Baifei Hu, Cheng Ye, Zhigang Zhang, Mingzhu Yin, Qiushi Cao, Yuanming Ba, Hongtao Liu.  (2022)  Stewed Rhubarb Decoction Ameliorates Adenine-Induced Chronic Renal Failure in Mice by Regulating Gut Microbiota Dysbiosis.  Frontiers in Pharmacology,  13  (842720).  [PMID:35392552] [10.3389/fphar.2022.842720]
6. Ying Xu, Xuan Yu, Jiaqi Gui, Yiqun Wan, Jinping Chen, Ting Tan, Fan Liu, Lan Guo.  (2022)  Ultrasonic Solvent Extraction Followed by Dispersive Solid Phase Extraction (d-SPE) Cleanup for the Simultaneous Determination of Five Anthraquinones in Polygonum multiflorum by UHPLC-PDA.  Foods,  11  (3): (386).  [PMID:35159536] [10.3390/foods11030386]
7. Chi Chen, Zhuang Fu, Weiying Zhou, Qiushi Chen, Chenzhao Wang, Lu Xu, Zhibing Wang, Hanqi Zhang.  (2020)  Ionic liquid-immobilized NaY zeolite-based matrix solid phase dispersion for the extraction of active constituents in Rheum palmatum L..  MICROCHEMICAL JOURNAL,  152  (104245).  [PMID:] [10.1016/j.microc.2019.104245]
8. Qingqing Hao, Lilin Lu, Xianwen Kan.  (2019)  Probe and analogue: Double roles of thionine for aloe-emodin selective and sensitive ratiometric detection.  SENSORS AND ACTUATORS B-CHEMICAL,  292  (247).  [PMID:] [10.1016/j.snb.2019.04.129]
9. Jian Lu, Yingying Qin, Qi Zhang, Chao Yu, Yilin Wu, Yongsheng Yan, Hougang Fan, Minjia Meng, Chunxiang Li.  (2019)  Antibacterial, high-flux and 3D porous molecularly imprinted nanocomposite sponge membranes for cross-flow filtration of emodin from analogues.  CHEMICAL ENGINEERING JOURNAL,  360  (483).  [PMID:] [10.1016/j.cej.2018.12.014]
10. Wang Qianqian, Xu Yixiang, Xu Jiaqi, Wang Xudong, Shen Chen, Zhang Yan, Liu Xiufeng, Yu Boyang, Zhang Jian.  (2017)  Molecular cloning and expression of a glycosyltransferase from Bacillus subtilis for modification of morin and related polyphenols.  BIOTECHNOLOGY LETTERS,  39  (8): (1229-1235).  [PMID:28484911] [10.1007/s10529-017-2352-z]
11. Xiaoya Jiang, Xiaoyan Jiao, Doudou Zhang, Ligai Bai, Haiyan Liu, Hongyuan Yan.  (2017)  Fabrication of a polymer monolithic column via redox system and its application in efficient separation of Chinese herb Rheum palmatum L..  JOURNAL OF APPLIED POLYMER SCIENCE,  134  (21):   [PMID:] [10.1002/app.44874]
12. Xingqiang Wu, Shuxuan Liang, Xusheng Ge, Yunkai Lv, Hanwen Sun.  (2015)  Synthesis and evaluation of dummy molecularly imprinted microspheres for the specific solid-phase extraction of six anthraquinones from slimming tea.  JOURNAL OF SEPARATION SCIENCE,  38  (8): (1263-1270).  [PMID:25677958] [10.1002/jssc.201401341]
13. Gong Hao, He Zihao, Peng Anlin, Zhang Xin, Cheng Biao, Sun Yue, Zheng Ling, Huang Kun.  (2014)  Effects of several quinones on insulin aggregation.  Scientific Reports,  (1): (1-8).  [PMID:25008537] [10.1038/srep05648]

References

1. Baqi Y, Atzler K, Köse M, Glänzel M, Müller CE.  (2009)  High-affinity, non-nucleotide-derived competitive antagonists of platelet P2Y12 receptors..  J Med Chem,  52  (12): (3784-93).  [PMID:19463000] [10.1021/op500134e]
2. Tom Coenye,Kris Honraet,Petra Rigole,Pol Nadal Jimenez,Hans J Nelis.  (2007-01-16)  In vitro inhibition of Streptococcus mutans biofilm formation on hydroxyapatite by subinhibitory concentrations of anthraquinones..  Antimicrobial agents and chemotherapy,  51  ((4)): (1541-1544).  [PMID:17220400]
3. Xing-Ri Cui,Maiko Tsukada,Nao Suzuki,Takeshi Shimamura,Li Gao,Jyunichi Koyanagi,Fusao Komada,Setsuo Saito.  (2007-10-24)  Comparison of the cytotoxic activities of naturally occurring hydroxyanthraquinones and hydroxynaphthoquinones..  European journal of medicinal chemistry,  43  ((6)): (1206-1215).  [PMID:17949858]
4. Junko Koyama,Yu Nisino,Izumi Morita,Norihiro Kobayashi,Toshiyuki Osakai,Harukuni Tokuda.  (2008-06-17)  Correlation between reduction potentials and inhibitions of Epstein-Barr virus activation by anthraquinone derivatives..  Bioorganic & medicinal chemistry letters,  18  ((14)): (4106-4109).  [PMID:18556196]
5. Francesca Sorrentino,Anastasia Karioti,Paola Gratteri,Maria Pia Rigobello,Guido Scutari,Luigi Messori,Alberto Bindoli,Matteo Chioccioli,Chiara Gabbiani,Maria Camilla Bergonzi,Anna Rita Bilia.  (2010-11-26)  Hypericins and thioredoxin reductase: Biochemical and docking studies disclose the molecular basis for effective inhibition by naphthodianthrones..  Bioorganic & medicinal chemistry,  19  ((1)): (631-641).  [PMID:21106380]
6. Khalilah Haris,Samhani Ismail,Zamzuri Idris,Jafri Malin Abdullah,Abdul Aziz Mohamed Yusoff.  (2014-06-28)  Expression profile of genes modulated by Aloe emodin in human U87 glioblastoma cells..  Asian Pacific journal of cancer prevention : APJCP,  15  ((11)): (4499-4505).  [PMID:24969876]
7. Naraganahalli R Thimmegowda,Chanmi Park,Bettaswamigowda Shwetha,Krisada Sakchaisri,Kangdong Liu,Joonsung Hwang,Sangku Lee,Sook J Jeong,Nak K Soung,Jae H Jang,In-Ja Ryoo,Jong S Ahn,Raymond L Erikson,Bo Y Kim.  (2014-10-18)  Synthesis and antitumor activity of natural compound aloe emodin derivatives..  Chemical biology & drug design,  85  ((5)): (638-644).  [PMID:25323822]
8. Mildred Acevedo-Duncan,Christopher Russell,Sapna Patel,Rekha Patel.  (2004-11-09)  Aloe-emodin modulates PKC isozymes, inhibits proliferation, and induces apoptosis in U-373MG glioma cells..  International immunopharmacology,  ((14)): (1775-1784).  [PMID:15531293]
9. Xia Zhou,Baoan Song,Linhong Jin,Deyu Hu,Chunling Diao,Guangfang Xu,Zhihui Zou,Song Yang.  (2005-11-09)  Isolation and inhibitory activity against ERK phosphorylation of hydroxyanthraquinones from rhubarb..  Bioorganic & medicinal chemistry letters,  16  ((3)): (563-568).  [PMID:16275083]
10. Jun-ming Guo,Bing-xiu Xiao,Qiong Liu,Shun Zhang,Dong-hai Liu,Zhao-hui Gong.  (2007-11-23)  Anticancer effect of aloe-emodin on cervical cancer cells involves G2/M arrest and induction of differentiation..  Acta pharmacologica Sinica,  28  ((12)): (1991-1995).  [PMID:18031614]
11. Yiqun Du,Jian Zhang,Zhonghua Tao,Chenchen Wang,Shiyan Yan,Xiaowei Zhang,Mingzhu Huang.  (2019-05-28)  Aloe emodin exerts potent anticancer effects in MIAPaCa-2 and PANC-1 human pancreatic adenocarcinoma cell lines through activation of both apoptotic and autophagic pathways, sub-G1 cell cycle arrest and disruption of mitochondrial membrane potential (ΛΨm)..  Journal of B.U.ON. : official journal of the Balkan Union of Oncology,  24  ((2)): (746-753).  [PMID:31128032]
12. Wenbin Chen, Airi N. Kato, Lijun Dai, Paul S. Clegg, Tao Li.  (2023)  Continuous Emulsion Channels Achieved by Controlling the Aqueous–Oil Interface Solely with Rough Colloids.  ADVANCED FUNCTIONAL MATERIALS,  34  (6): (2308608).  [PMID:9647693] [10.1002/adfm.202308608]
13. Mengsi Zhang, Lu Wang, Hao Jin, Nan Zhao, Yi Liu, Shijie Lan, Shuwei Liu, Hao Zhang.  (2023)  Employing single valency polyphenol to prepare metal-phenolic network antitumor reagents through FeOOH assistance.  JOURNAL OF CONTROLLED RELEASE,  358  (612).  [PMID:37196899] [10.1016/j.jconrel.2023.05.020]
14. Huijie Gao, Yan Ren, Chao Liu.  (2022)  Aloe-Emodin Suppresses Oxidative Stress and Inflammation via a PI3K-Dependent Mechanism in a Murine Model of Sepsis.  Evidence-based Complementary and Alternative Medicine,  2022  (9697887).  [PMID:35978995] [10.1155/2022/9697887]
15. Yuanyuan Song, Ziqi Wang, Yijing Long, Yang Mao, Feng Jiang, Yuanyuan Lu.  (2022)  2-Alkyl-anthraquinones inhibit Candida albicans biofilm via inhibiting the formation of matrix and hyphae.  RESEARCH IN MICROBIOLOGY,  173  (103955).  [PMID:35550403] [10.1016/j.resmic.2022.103955]
16. Rui Wang, Baifei Hu, Cheng Ye, Zhigang Zhang, Mingzhu Yin, Qiushi Cao, Yuanming Ba, Hongtao Liu.  (2022)  Stewed Rhubarb Decoction Ameliorates Adenine-Induced Chronic Renal Failure in Mice by Regulating Gut Microbiota Dysbiosis.  Frontiers in Pharmacology,  13  (842720).  [PMID:35392552] [10.3389/fphar.2022.842720]
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Solution Calculators