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Home Bioactive Small Molecules Alosetron Hydrochloride - ≥98% (HPLC), high purity , Serotonin 3a (5-HT3a) receptor antagonist, CAS No.122852-69-1, Serotonin 3a (5-HT3a) receptor antagonist
Alosetron Hydrochloride - ≥98% (HPLC), high purity , Serotonin 3a (5-HT3a) receptor antagonist, CAS No.122852-69-1, Serotonin 3a (5-HT3a) receptor antagonist
Basic Description Synonyms ALOSETRON HYDROCHLORIDE | 122852-69-1 | Alosetron HCl | Lotronex | GR 68755c | Lotrpnex | Alosetron (Hydrochloride) | 132414-02-9 | Alosetron Hydrochloride(1:X) | Alosetron hydrochloride [USAN] | HSDB 7055 | UNII-2F5R1A46YW | GR-68755C | 2F5R1A46YW | 5-methyl-2-[(5-methyl-1H-imidazo Specifications & Purity ≥98%(HPLC) Biochemical and Physiological Mechanisms Alosetron is a potent and highly selective antagonist of serotonin 5-HT3 receptors, nonselective cation channels found predominantly in the enteric nervous system of the gastrointestinal tract. These receptors are involved in the regulation of visceral pa Storage Temp Store at -20°C Shipped In Ice chest + Ice pads Action Type ANTAGONIST Mechanism of action Serotonin 3a (5-HT3a) receptor antagonist
Associated Targets(Human) Associated Targets(non-human) Names and Identifiers Pubchem Sid 488183406 Pubchem Sid Url https://pubchem.ncbi.nlm.nih.gov/substance/488183406 IUPAC Name 5-methyl-2-[(5-methyl-1H-imidazol-4-yl)methyl]-3,4-dihydropyrido[4,3-b]indol-1-one;hydrochloride INCHI InChI=1S/C17H18N4O.ClH/c1-11-13(19-10-18-11)9-21-8-7-15-16(17(21)22)12-5-3-4-6-14(12)20(15)2;/h3-6,10H,7-9H2,1-2H3,(H,18,19);1H InChi Key FNYQZOVOVDSGJH-UHFFFAOYSA-N Canonical SMILES CC1=C(N=CN1)CN2CCC3=C(C2=O)C4=CC=CC=C4N3C.Cl Isomeric SMILES CC1=C(N=CN1)CN2CCC3=C(C2=O)C4=CC=CC=C4N3C.Cl WGK Germany 3 PubChem CID 60758 Molecular Weight 330.81
Chemical and Physical Properties Sensitivity Moisture & heat sensitive Melt Point(°C) 291 °C
Safety and Hazards(GHS) Pictogram(s) GHS06 , GHS07 Signal Danger Hazard Statements H319: Causes serious eye irritation
H301: Toxic if swallowed
H412: Harmful to aquatic life with long lasting effects
Precautionary Statements P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.
P273: Avoid release to the environment.
P280: Wear protective gloves/protective clothing/eye protection/face protection.
P321: Specific treatment (see ... on this label).
P405: Store locked up.
P501: Dispose of contents/container to ...
P264: Wash hands [and …] thoroughly after handling.
P270: Do not eat, drink or smoke when using this product.
P330: Rinse mouth.
P264+P265: Wash hands [and …] thoroughly after handling. Do not touch eyes.
P301+P316: IF SWALLOWED: Get emergency medical help immediately.
P337+P317: If eye irritation persists: Get medical help.
WGK Germany 3 Merck Index 308
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