Alsterpaullone - 98%, high purity , CAS No.237430-03-4, Inhibitor of cyclin dependent kinase 1;Inhibitor of glycogen synthase kinase 3 beta

Item Number

A274619

• Synonyms: BDBM7262 | EX-A4771 | CS-0028454 | HMS2043P15 | 9-nitro-7,12-dihydro-5H-indolo[3,2-d][1]benzazepin-6-one | J-015199 | BRD-K17516382-001-01-7 | 9-nitro-7,12-dihydroindolo(3,2-d)(1)benzazepin-6(5H)-one | 14-nitro-8,18-diazatetracyclo[9.7.0.0;{2,7}.0;{12,17}
• Specifications & Purity: Moligand™, ≥98%
• Biochemical and Physiological Mechanisms: Potent CDK inhibitor (IC 50 values are 3.5 (CDK1/cyclin B), 20 (CDK2/cyclin A) and 40 nM (CDK5/p35)). Also displays potent and selective inhibition of GSK-3β (IC 50 values are 40 and 4 nM respectively). Antiproliferative effects seen in vitro .
• Storage Temp: Store at -20°C,Desiccated
• Shipped In: Ice chest + Ice pads
• Grade: Moligand™
• Action Type: INHIBITOR
• Mechanism of action: Inhibitor of cyclin dependent kinase 1;Inhibitor of glycogen synthase kinase 3 beta
• Note: Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.