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Alternariol - 96%, high purity , CAS No.641-38-3

3 Citations

≥96%

CAS#: 641-38-3
Formula: C₁₄H₁₀O₅
Molecular Weight: 258.23
Beilstein Registry Number: 244839
MDL number: MFCD00133068
PubChem CID: 5359485

Item Number

A134401

Grouped product items
SKU	Size	Availability	Price	Qty
A134401-1mg	1mg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$444.90
A134401-5mg	5mg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$1,335.90

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Cell Cycle/DNA Damage Topoisomerase

Basic Description

Synonyms	Alternariol, analytical standard \| CHEBI:64983 \| ACon0_000598 \| NCGC00180653-01 \| A867945 \| Alternariol from Alternaria sp., ~96% \| CEBXXEKPIIDJHL-UHFFFAOYSA-N \| Alternariol from Alternaria sp. \| Alternariol \| MFCD00133068 \| Q410677 \| Alternariol 3,4',5-T
Specifications & Purity	≥96%
Biochemical and Physiological Mechanisms	Alternaria mycotoxins are generally associated with undried food grains post-harvest. The disease caused by Alternaria mycotoxin results in a discolored halo in fruits and spotting in leaves. Alternariol (AOH) is cytotoxic and fetotoxic to microbes and ma
Source	from Alternaria sp
Storage Temp	Store at -20°C,Argon charged
Shipped In	Ice chest + Ice pads
Product Description	Product Description： Alternariol belongs to the dibenzo-pyrones chemical group. It is a mycotoxin present in indoor air, soil and plants. Product Application： Alternariol from Alternaria sp. may be used as a calibration standard in reverse phase high-performance liquid chromatography (HPLC) and UV-spectrum analysis. It may also be used to spike wholemeal wheat flour for wet baking studies.

Associated Targets(Human)

EGFR Tclin Epidermal growth factor receptor erbB1 (33727 Activities)

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INSR Tclin Insulin receptor (5558 Activities)

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ERBB2 Tclin Receptor protein-tyrosine kinase erbB-2 (7851 Activities)

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PDGFRB Tclin Platelet-derived growth factor receptor beta (5195 Activities)

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IGF1R Tclin Insulin-like growth factor I receptor (8605 Activities)

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CSNK2A1 Tchem Casein kinase II alpha (3512 Activities)

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SRC Tclin Tyrosine-protein kinase SRC (10310 Activities)

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AURKB Tchem Serine/threonine-protein kinase Aurora-B (6805 Activities)

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PLK1 Tchem Serine/threonine-protein kinase PLK1 (28605 Activities)

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KDR Tclin Vascular endothelial growth factor receptor 2 (20924 Activities)

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PTK2 Tclin Focal adhesion kinase 1 (4730 Activities)

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MET Tclin Hepatocyte growth factor receptor (10718 Activities)

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CDK2 Tchem Cyclin-dependent kinase 2 (9050 Activities)

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FLT4 Tclin Vascular endothelial growth factor receptor 3 (3216 Activities)

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AKT1 Tchem Serine/threonine-protein kinase AKT (9192 Activities)

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FLT3 Tclin Tyrosine-protein kinase receptor FLT3 (13481 Activities)

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TEK Tclin Tyrosine-protein kinase TIE-2 (3348 Activities)

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AURKA Tchem Serine/threonine-protein kinase Aurora-A (10240 Activities)

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PLK4 Tchem Serine/threonine-protein kinase PLK4 (1882 Activities)

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A498 (42825 Activities)

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ACHN (49357 Activities)

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CAKI-1 (44928 Activities)

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CCRF-CEM (65223 Activities)

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COLO 205 (50209 Activities)

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DLD-1 (17511 Activities)

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DMS-273 (14108 Activities)

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HL-60 (67320 Activities)

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HT-29 (80576 Activities)

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K562 (73714 Activities)

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KM12 (47707 Activities)

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M14 (47487 Activities)

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MCF7 (126967 Activities)

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MOLT-4 (49676 Activities)

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OVCAR-3 (48710 Activities)

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OVCAR-4 (44535 Activities)

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OVCAR-5 (45555 Activities)

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OVCAR-8 (47708 Activities)

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RXF 393 (41971 Activities)

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RXF 631 (11415 Activities)

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SF-295 (48000 Activities)

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SK-MEL-2 (46422 Activities)

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SK-MEL-28 (48833 Activities)

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SK-MEL-5 (47095 Activities)

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SK-OV-3 (52876 Activities)

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SN12C (47755 Activities)

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SNB-19 (46794 Activities)

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SNB-78 (14240 Activities)

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TK-10 (45540 Activities)

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U-251 (51189 Activities)

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UACC-257 (46019 Activities)

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Associated Targets(non-human)

Streptococcus pneumoniae (31063 Activities)

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Pseudomonas aeruginosa (123386 Activities)

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Agrobacterium tumefaciens (620 Activities)

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Enterobacter cloacae (7976 Activities)

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Klebsiella pneumoniae (43867 Activities)

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Staphylococcus aureus (210822 Activities)

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Staphylococcus haemolyticus (1695 Activities)

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Acinetobacter baumannii (41033 Activities)

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Escherichia coli (133304 Activities)

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Enterococcus faecium (13803 Activities)

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Bacillus subtilis (32866 Activities)

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Pichia kudriavzevii (7448 Activities)

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Aspergillus fumigatus (16427 Activities)

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Candida albicans (78123 Activities)

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L5178Y (1809 Activities)

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RAW264.7 (28094 Activities)

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Pyricularia oryzae (1832 Activities)

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Xanthomonas euvesicatoria (74 Activities)

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Aspergillus ficuum (42 Activities)

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Mechanisms of Action

Mechanism of Action	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	References

Names and Identifiers

IUPAC Name	3,7,9-trihydroxy-1-methylbenzo[c]chromen-6-one
INCHI	InChI=1S/C14H10O5/c1-6-2-7(15)5-11-12(6)9-3-8(16)4-10(17)13(9)14(18)19-11/h2-5,15-17H,1H3
InChi Key	CEBXXEKPIIDJHL-UHFFFAOYSA-N
Canonical SMILES	CC1=CC(=CC2=C1C3=C(C(=CC(=C3)O)O)C(=O)O2)O
Isomeric SMILES	CC1=CC(=CC2=C1C3=C(C(=CC(=C3)O)O)C(=O)O2)O
WGK Germany	3
RTECS	HP8757000
PubChem CID	5359485
Molecular Weight	258.23
Beilstein	244839

Certificates

Certificate of Analysis(COA)

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3 results found

Lot Number	Certificate Type	Date	Item
G2219045	Certificate of Analysis	May 15, 2024	A134401
G2219046	Certificate of Analysis	May 15, 2024	A134401
K2112038	Certificate of Analysis	Aug 17, 2023	A134401

Chemical and Physical Properties

Solubility	DMSO (Slightly), Methanol (Slightly)
Sensitivity	Light sensitive,Moisture sensitive
Melt Point(°C)	>300°C (dec.)

Safety and Hazards(GHS)

Pictogram(s)	GHS06
Signal	Danger
Hazard Statements	H300:Fatal if swallowed H310:Fatal in contact with skin H330:Fatal if inhaled
Precautionary Statements	P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P260:Do not breathe dust/fume/gas/mist/vapors/spray. P284:[In case of inadequate ventilation] Wear respiratory protection. P271:Use only outdoors or in a well-ventilated area. P270:Do not eat, drink or smoke when using this product. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P330:Rinse mouth. P262:Do not get in eyes, on skin, or on clothing. P320:Specific treatment is urgent (see ... on this label). P361+P364:Take off immediately all contaminated clothing and wash it before reuse. P301+P316:IF SWALLOWED: Get emergency medical help immediately. P316:Get emergency medical help immediately.
WGK Germany	3
RTECS	HP8757000

Citations of This Product

How to Cite Aladdin Scientific Products?

1. Hu Xiaopeng, Xia Yide, Liu Yiwei, Zhao Faqiong, Zeng Baizhao. (2021) Determination of patulin using dual-dummy templates imprinted electrochemical sensor with PtPd decorated N-doped porous carbon for amplification. MICROCHIMICA ACTA, 188 (5): (1-9). [PMID:33797604] [10.1007/s00604-021-04812-2]
2. Feng Wang, De-Bin Wan, Yu-Dong Shen, Yuan-Xin Tian, Zhi-Li Xiao, Zhen-Lin Xu, Jin-Yi Yang, Yuan-Ming Sun, Bruce D. Hammock, Hong Wang. (2021) Development of a chemiluminescence immunoassay for detection of tenuazonic acid mycotoxin in fruit juices with a specific camel polyclonal antibody. Analytical Methods, 13 (15): (1795-1802). [PMID:33885655] [10.1039/D1AY00200G]
3. Feng Wang, Zhen-Feng Li, Yuan-Yuan Yang, De-Bin Wan, Natalia Vasylieva, Yu-Qi Zhang, Jun Cai, Hong Wang, Yu-Dong Shen, Zhen-Lin Xu, Bruce D. Hammock. (2020) Chemiluminescent Enzyme Immunoassay and Bioluminescent Enzyme Immunoassay for Tenuazonic Acid Mycotoxin by Exploitation of Nanobody and Nanobody–Nanoluciferase Fusion. ANALYTICAL CHEMISTRY, 92 (17): (11935–11942). [PMID:32702970] [10.1021/acs.analchem.0c02338]

References

1. Hu Xiaopeng, Xia Yide, Liu Yiwei, Zhao Faqiong, Zeng Baizhao. (2021) Determination of patulin using dual-dummy templates imprinted electrochemical sensor with PtPd decorated N-doped porous carbon for amplification. MICROCHIMICA ACTA, 188 (5): (1-9). [PMID:33797604] [10.1007/s00604-021-04812-2]
2. Feng Wang, De-Bin Wan, Yu-Dong Shen, Yuan-Xin Tian, Zhi-Li Xiao, Zhen-Lin Xu, Jin-Yi Yang, Yuan-Ming Sun, Bruce D. Hammock, Hong Wang. (2021) Development of a chemiluminescence immunoassay for detection of tenuazonic acid mycotoxin in fruit juices with a specific camel polyclonal antibody. Analytical Methods, 13 (15): (1795-1802). [PMID:33885655] [10.1039/D1AY00200G]
3. Feng Wang, Zhen-Feng Li, Yuan-Yuan Yang, De-Bin Wan, Natalia Vasylieva, Yu-Qi Zhang, Jun Cai, Hong Wang, Yu-Dong Shen, Zhen-Lin Xu, Bruce D. Hammock. (2020) Chemiluminescent Enzyme Immunoassay and Bioluminescent Enzyme Immunoassay for Tenuazonic Acid Mycotoxin by Exploitation of Nanobody and Nanobody–Nanoluciferase Fusion. ANALYTICAL CHEMISTRY, 92 (17): (11935–11942). [PMID:32702970] [10.1021/acs.analchem.0c02338]

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Alternariol - 96%, high purity , CAS No.641-38-3

Basic Description

Associated Targets(Human)

Associated Targets(non-human)

Mechanisms of Action

Names and Identifiers

Certificates

Certificate of Analysis(COA)

Chemical and Physical Properties

Safety and Hazards(GHS)

Related Documents

Citations of This Product

References

Solution Calculators

Molarity Calculator

Dilution Calculator

Reconstitution Calculator