JavaScript seems to be disabled in your browser. For the best experience on our site, be sure to turn on Javascript in your browser.

྾

Home
Applications
Targets
G protein-coupled receptors (GPCRs)
Bombesin receptors
AM-37 , CAS No.A607583, Antagonist of BB 2 receptor

Skip to the end of the images gallery

Skip to the beginning of the images gallery

AM-37 , CAS No.A607583, Antagonist of BB 2 receptor

Moligand™

PubChem CID: 122181321

Item Number

A607583

Grouped product items
SKU	Size	Availability	Price	Qty
A607583-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$1,334.90
A607583-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$2,000.90

View related series

BB2 receptor Antagonist

Basic Description

Specifications & Purity	Moligand™
Grade	Moligand™
Action Type	ANTAGONIST
Mechanism of action	Antagonist of BB 2 receptor

Associated Targets(Human)

GRPR Tchem Gastrin-releasing peptide receptor (0 Activities)

Discover Target: GRPR

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

FPR1 Tchem Formyl peptide receptor 1 (1372 Activities)

Discover Target: FPR1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

FPR2 Tchem Lipoxin A4 receptor (3472 Activities)

Discover Target: FPR2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mechanisms of Action

Mechanism of Action	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	References

Names and Identifiers

IUPAC Name	(2R)-3-(1H-indol-3-yl)-2-[(4-methoxyphenyl)carbamoylamino]-N-[(1-pyridin-3-ylcyclohexyl)methyl]propanamide
INCHI	InChI=1S/C31H35N5O3/c1-39-25-13-11-24(12-14-25)35-30(38)36-28(18-22-19-33-27-10-4-3-9-26(22)27)29(37)34-21-31(15-5-2-6-16-31)23-8-7-17-32-20-23/h3-4,7-14,17,19-20,28,33H,2,5-6,15-16,18,21H2,1H3,(H,34,37)(H2,35,36,38)/t28-/m1/s1
InChi Key	INNVRNIOVHJSQS-MUUNZHRXSA-N
Canonical SMILES	COc1ccc(cc1)NC(=O)N[C@@H](C(=O)NCC1(CCCCC1)c1cccnc1)Cc1c[nH]c2c1cccc2
Isomeric SMILES	COC1=CC=C(C=C1)NC(=O)N[C@H](CC2=CNC3=CC=CC=C32)C(=O)NCC4(CCCCC4)C5=CN=CC=C5
PubChem CID	122181321

Database links

PubChem CID	122181321
BindingDB Ligand	50097560
ChEMBL Ligand	CHEMBL3590072
GPCRdb Ligand	AM-37

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

References

1. Moody TW, Tashakkori N, Mantey SA, Moreno P, Ramos-Alvarez I, Leopoldo M, Jensen RT. (2017) AM-37 and ST-36 Are Small Molecule Bombesin Receptor Antagonists.. Front Endocrinol (Lausanne), 8 (13): (176). [PMID:28785244] [10.1021/op500134e]

Solution Calculators

Molarity Calculator

Determine the necessary mass, volume, or concentration for preparing a solution.

Dilution Calculator

Determine the dilution needed to prepare a stock solution.