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Transmembrane Transporters
Voltage-gated ion channels
Transient Receptor Potential channels (TRP)
AM12 , CAS No.A607573, Channel blocker of TRPC5

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AM12 , CAS No.A607573, Channel blocker of TRPC5

Moligand™

PubChem CID: 137553166

Item Number

A607573

Grouped product items
SKU	Size	Availability	Price	Qty
A607573-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$1,334.90
A607573-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$2,000.90

View related series

TRPC5 Channel blocker

Basic Description

Synonyms	3,5,7-trihydroxy-2-(2-bromophenyl)-4H-chromen-4-one;AM-12
Specifications & Purity	Moligand™
Grade	Moligand™
Action Type	CHANNEL BLOCKER
Mechanism of action	Channel blocker of TRPC5

Associated Targets(Human)

TRPC5 Tchem Short transient receptor potential channel 5 (2 Activities)

Discover Target: TRPC5

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

TRPC5 Tchem Short transient receptor potential channel 5 (300 Activities)

Discover Target: TRPC5

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

TRPC5 Tchem TRPC1/TRPC5 (2 Activities)

Discover Target: TRPC5

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Associated Targets(non-human)

Trpc4 Short transient receptor potential channel 4 (1615 Activities)

Discover Target: Trpc4

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Names and Identifiers

IUPAC Name	2-(2-bromophenyl)-3,5,7-trihydroxy-4H-chromen-4-one
INCHI	InChI=1S/C15H9BrO5/c16-9-4-2-1-3-8(9)15-14(20)13(19)12-10(18)5-7(17)6-11(12)21-15/h1-6,17-18,20H
InChi Key	OVIAJBSVWWYJSD-UHFFFAOYSA-N
Canonical SMILES	Oc1cc(O)c2c(c1)oc(c(c2=O)O)c1ccccc1Br
Isomeric SMILES	C1=CC=C(C(=C1)C2=C(C(=O)C3=C(C=C(C=C3O2)O)O)O)Br
PubChem CID	137553166

Database links

PubChem CID	137553166

Certificates

Certificate of Analysis(COA)

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References

1. Naylor J, Minard A, Gaunt HJ, Amer MS, Wilson LA, Migliore M, Cheung SY, Rubaiy HN, Blythe NM, Musialowski KE et al.. (2016) Natural and synthetic flavonoid modulation of TRPC5 channels.. Br J Pharmacol, 173 (3): (562-74). [PMID:26565375]

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AM12 , CAS No.A607573, Channel blocker of TRPC5

Basic Description

Associated Targets(Human)

Associated Targets(non-human)

Names and Identifiers

Database links

Certificates

Certificate of Analysis(COA)

Related Documents

References

Solution Calculators

Molarity Calculator

Dilution Calculator

Reconstitution Calculator