Determine the necessary mass, volume, or concentration for preparing a solution.
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SKU | Size | Availability | Price | Qty |
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A125972-5mg | 5mg | In stock | $1,342.90 | |
A125972-10mg | 10mg | In stock | $1,725.90 | |
A125972-25mg | 25mg | In stock | $2,472.90 | |
A125972-50mg | 50mg | In stock | $4,647.90 |
Synonyms | Omadacycline | Amadacycline | 389139-89-3 | nuzyra | PTK 0796 | Omadacycline [USAN] | PTK-0796 | PTK 0796;Amadacycline | BAY 73-6944 | 090IP5RV8F | 389139-89-3 (free base) | (4S,4aS,5aR,12aR)-4,7-bis(dimethylamino)-9-[(2,2-dimethylpropylamino)methyl]-1,10,11,12a-tetrahydroxy-3 |
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Specifications & Purity | Moligand™, ≥98% |
Biochemical and Physiological Mechanisms | Description: IC50 Value: N/A Amadacyclin is a new tetracycline antibiotic in the pipeline, which can inhibit the 30s subunit of bacterial ribosome. in vitro: in vivo: Clinical trial: Phase III Study to Compare the Safety and Efficacy of P |
Storage Temp | Store at -20°C |
Shipped In | Ice chest + Ice pads |
Grade | Moligand™ |
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Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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IUPAC Name | (4S,4aS,5aR,12aR)-4,7-bis(dimethylamino)-9-[(2,2-dimethylpropylamino)methyl]-1,10,11,12a-tetrahydroxy-3,12-dioxo-4a,5,5a,6-tetrahydro-4H-tetracene-2-carboxamide |
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INCHI | InChI=1S/C29H40N4O7/c1-28(2,3)12-31-11-14-10-17(32(4)5)15-8-13-9-16-21(33(6)7)24(36)20(27(30)39)26(38)29(16,40)25(37)18(13)23(35)19(15)22(14)34/h10,13,16,21,31,34-35,38,40H,8-9,11-12H2,1-7H3,(H2,30,39)/t13-,16-,21-,29-/m0/s1 |
InChi Key | VJYKVCURWJGLPG-IQZGDKDPSA-N |
Canonical SMILES | CC(C)(C)CNCC1=CC(=C2CC3CC4C(C(=O)C(=C(C4(C(=O)C3=C(C2=C1O)O)O)O)C(=O)N)N(C)C)N(C)C |
Isomeric SMILES | CC(C)(C)CNCC1=CC(=C2C[C@H]3C[C@H]4[C@@H](C(=O)C(=C([C@]4(C(=O)C3=C(C2=C1O)O)O)O)C(=O)N)N(C)C)N(C)C |
PubChem CID | 54697325 |
Molecular Weight | 556.65 |
CAS Registry No. | 389139-89-3 |
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PubChem CID | 54697325 |
ChEMBL Ligand | CHEMBL1689772 |
Antibiotic DB | 246 |
Enter Lot Number to search for COA:
Find and download the COA for your product by matching the lot number on the packaging.
Lot Number | Certificate Type | Date | Item |
---|---|---|---|
K2413027 | Certificate of Analysis | Nov 21, 2024 | A125972 |
J2214302 | Certificate of Analysis | Jul 19, 2024 | A125972 |
J2214303 | Certificate of Analysis | Jul 19, 2024 | A125972 |
J2214304 | Certificate of Analysis | Jul 19, 2024 | A125972 |
J2214320 | Certificate of Analysis | Jul 19, 2024 | A125972 |
Solubility | 25°C: DMSO |
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Pictogram(s) | GHS08, GHS07 |
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Signal | Warning |
Hazard Statements | H302:Harmful if swallowed H361:Suspected of damaging fertility or the unborn child |
Precautionary Statements | P280:Wear protective gloves/protective clothing/eye protection/face protection. P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P270:Do not eat, drink or smoke when using this product. P330:Rinse mouth. P203:Obtain, read and follow all safety instructions before use. P301+P317:IF SWALLOWED: Get medical help. P318:if exposed or concerned, get medical advice. |
1. Clark RB, He M, Fyfe C, Lofland D, O'Brien WJ, Plamondon L, Sutcliffe JA, Xiao XY. (2011) 8-Azatetracyclines: synthesis and evaluation of a novel class of tetracycline antibacterial agents.. J Med Chem, 54 (5): (1511-28). [PMID:21302930] [10.1021/op500134e] |