Amiloride hydrochloride dihydrate is a potent epithelial sodium channel blocker and selective low threshold (T-type) calcium channel protein inhibitor (KD=30μM).
Storage Temp
Store at -20°C
Shipped In
Ice chest + Ice pads
Action Type
BLOCKER
Mechanism of action
Amiloride-sensitive sodium channel, ENaC blocker
Product Description
Amiloride HCl dihydrate is a potent epithelial sodium channel blocker. An epithelial sodium channel blocker
1.Siying Chen, Zhicheng Le, Jiayue Gu, Lixin Liu, Zhijia Liu, Yongming Chen. (2023) Exploring the Effect of Amphiphile Architecture on Intracellular Protein Delivery Capacity: Dimeric versus Trimeric Amphiphiles. ACS Applied Materials & Interfaces, 15 (22):(26328–26339). [PMID:37219911][10.1021/acsami.3c02198]
2.Shengnan Ma, Lei Song, Yueyue Bai, Shihao Wang, Jiao Wang, Haohao Zhang, Fazhan Wang, Yiyan He, Chuntao Tian, Guijun Qin. (2023) Improved intracellular delivery of exosomes by surface modification with fluorinated peptide dendrimers for promoting angiogenesis and migration of HUVECs. RSC Advances, 13 (17):(11269-11277). [PMID:37057265][10.1039/D3RA00300K]
3.Zhang DL, Sun YJ, Ma ML, Wang YJ, Lin H, Li RR, Liang ZL, Gao Y, Yang Z, He DF et al.. (2018) Gq activity- and β-arrestin-1 scaffolding-mediated ADGRG2/CFTR coupling are required for male fertility.. Elife, 7 (13):(1755-70). [PMID:29393851][10.1021/op500134e]
References
1.Siying Chen, Zhicheng Le, Jiayue Gu, Lixin Liu, Zhijia Liu, Yongming Chen. (2023) Exploring the Effect of Amphiphile Architecture on Intracellular Protein Delivery Capacity: Dimeric versus Trimeric Amphiphiles. ACS Applied Materials & Interfaces, 15 (22):(26328–26339). [PMID:37219911][10.1021/acsami.3c02198]
2.Shengnan Ma, Lei Song, Yueyue Bai, Shihao Wang, Jiao Wang, Haohao Zhang, Fazhan Wang, Yiyan He, Chuntao Tian, Guijun Qin. (2023) Improved intracellular delivery of exosomes by surface modification with fluorinated peptide dendrimers for promoting angiogenesis and migration of HUVECs. RSC Advances, 13 (17):(11269-11277). [PMID:37057265][10.1039/D3RA00300K]
3.Zhang DL, Sun YJ, Ma ML, Wang YJ, Lin H, Li RR, Liang ZL, Gao Y, Yang Z, He DF et al.. (2018) Gq activity- and β-arrestin-1 scaffolding-mediated ADGRG2/CFTR coupling are required for male fertility.. Elife, 7 (13):(1755-70). [PMID:29393851][10.1021/op500134e]
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J2429181