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Aminoglutethimide - 98%, high purity , Cytochrome P450 11A1 inhibitor, CAS No.125-84-8, Cytochrome P450 11A1 inhibitor

  • Moligand™
  • ≥98%
Item Number
A129479
Grouped product items
SKUSizeAvailabilityPrice Qty
A129479-200mg
200mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$11.90
A129479-1g
1g
In stock
$42.90
A129479-5g
5g
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$138.90
A129479-25g
25g
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$481.90
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CYP11A1 Inhibitor CYP19A1 Inhibitor

Basic Description

Synonymsaminoglutethimide|125-84-8|dl-Aminoglutethimide|Cytadren|Orimeten|p-Aminoglutethimide|Elipten|3-(4-aminophenyl)-3-ethylpiperidine-2,6-dione|3-(4-Aminophenyl)-3-ethyl-2,6-piperidinedione|Aminoglutetimida|Aminoglutethimidum|2-(p-Aminophenyl)-2-ethylglutarim
Specifications & PurityMoligand™, ≥98%
Biochemical and Physiological MechanismsDL-Aminoglutethimide is a derivative of the sedative glutethimide. Originally introduced as an anticonvulsant, it was found to cause adrenal insufficiency. Blocks adrenal steroidogenesis by inhibiting the enzymatic conversion of cholesterol to pregnenolon
GradeMoligand™
Action TypeINHIBITOR
Mechanism of actionCytochrome P450 11A1 inhibitor
Product Description

Application：

DL-Aminoglutethimide has been used:

as a steroid synthesis inhibitor to study its effects on steroid synthesis in amphibian Xenopus laevis oocytes

as an adrenostatic compound to study its effects on full form Enhanced green fluorescent protein (EGFP) andproopiomelanocortin (POMC) expression in the anterior domain of zebrafish pituitary corticotrophs

as an inhibitor of steroidogenic enzymes to study its effects on estrogen receptor (ER) mRNA levels in mouse tumor leydig cell line

Product Properties

ALogP1.2

Names and Identifiers

IUPAC Name 3-(4-aminophenyl)-3-ethylpiperidine-2,6-dione
INCHI InChI=1S/C13H16N2O2/c1-2-13(8-7-11(16)15-12(13)17)9-3-5-10(14)6-4-9/h3-6H,2,7-8,14H2,1H3,(H,15,16,17)
InChi Key ROBVIMPUHSLWNV-UHFFFAOYSA-N
Canonical SMILES CCC1(CCC(=O)NC1=O)C2=CC=C(C=C2)N
Isomeric SMILES CCC1(CCC(=O)NC1=O)C2=CC=C(C=C2)N
WGK Germany 3
RTECS MA4026950
PubChem CID 2145
Molecular Weight 232.278

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section

5 results found

Lot NumberCertificate TypeDateItem
F2403361Certificate of AnalysisMay 31, 2024 A129479
H2220149Certificate of AnalysisMay 31, 2024 A129479
H2220024Certificate of AnalysisJun 17, 2022 A129479
H2220148Certificate of AnalysisJun 17, 2022 A129479
K2324089Certificate of AnalysisJun 17, 2022 A129479

Chemical and Physical Properties

Melt Point(°C)152-154 °C

Safety and Hazards(GHS)

Pictogram(s) GHS07
Signal Warning
Hazard Statements

H315:Causes skin irritation

H319:Causes serious eye irritation

H335:May cause respiratory irritation

Precautionary Statements

P261:Avoid breathing dust/fume/gas/mist/vapors/spray.

P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352:IF ON SKIN: wash with plenty of water.

P321:Specific treatment (see ... on this label).

P405:Store locked up.

P501:Dispose of contents/container to ...

P264:Wash hands [and …] thoroughly after handling.

P271:Use only outdoors or in a well-ventilated area.

P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing.

P403+P233:Store in a well-ventilated place. Keep container tightly closed.

P362+P364:Take off contaminated clothing and wash it before reuse.

P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes.

P337+P317:If eye irritation persists: Get medical help.

P332+P317:If skin irritation occurs: Get medical help.

P319:Get medical help if you feel unwell.

WGK Germany 3
RTECS MA4026950

Related Documents

 SDS

 Specification Sheet

Solution Calculators

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