Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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A151036-25g | 25g | In stock | $39.90 | |
A151036-100g | 100g | In stock | $86.90 | |
A151036-500g | 500g | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $193.90 |
NOS inhibitor
Synonyms | Aminoguanidine hydrochloride|1937-19-5|16139-18-7|Pimagedine hydrochloride|Pimagedine HCl|Hydrazinecarboximidamide, monohydrochloride|Aminoguanidine HCl|Carbazamidine hydrochloride|Hydrazinecarboximidamide hydrochloride|Guanylhydrazine hydrochloride|1-ami |
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Specifications & Purity | ≥98%(T) |
Biochemical and Physiological Mechanisms | Inhibits both constitutive and inducible nitric oxide synthetase. .Irreversible inhibitor of iNOS, displaying 26-fold selectivity over nNOS. |
Storage Temp | Argon charged |
Shipped In | Normal |
Note | Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details. |
Product Description |
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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Pubchem Sid | 488192651 |
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Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/488192651 |
IUPAC Name | 2-aminoguanidine;hydrochloride |
INCHI | InChI=1S/CH6N4.ClH/c2-1(3)5-4;/h4H2,(H4,2,3,5);1H |
InChi Key | UBDZFAGVPPMTIT-UHFFFAOYSA-N |
Canonical SMILES | C(=NN)(N)N.Cl |
Isomeric SMILES | C(=NN)(N)N.Cl |
WGK Germany | 3 |
RTECS | ME8430000 |
PubChem CID | 2734687 |
UN Number | 3077 |
Packing Group | III |
Molecular Weight | 110.55 |
Reaxy-Rn | 3909606 |
Enter Lot Number to search for COA:
To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section
Lot Number | Certificate Type | Date | Item |
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G2411189 | Certificate of Analysis | Jun 12, 2024 | A151036 |
H2401291 | Certificate of Analysis | Jun 12, 2024 | A151036 |
F2427097 | Certificate of Analysis | Jun 12, 2024 | A151036 |
B2317253 | Certificate of Analysis | Dec 21, 2023 | A151036 |
H2328163 | Certificate of Analysis | Aug 12, 2023 | A151036 |
H2328164 | Certificate of Analysis | Aug 12, 2023 | A151036 |
H2328165 | Certificate of Analysis | Aug 12, 2023 | A151036 |
B2317192 | Certificate of Analysis | Jan 04, 2023 | A151036 |
B2317278 | Certificate of Analysis | Jan 04, 2023 | A151036 |
B2317323 | Certificate of Analysis | Jan 04, 2023 | A151036 |
B2317324 | Certificate of Analysis | Jan 04, 2023 | A151036 |
Solubility | DMSO (Slightly), Methanol (Slightly) |
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Sensitivity | Air & Moisture & heat & light sensitive |
Melt Point(°C) | 162-166 °C |
Pictogram(s) | GHS09, GHS07 |
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Signal | Warning |
Hazard Statements | H411:Toxic to aquatic life with long lasting effects H317:May cause an allergic skin reaction |
Precautionary Statements | P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P273:Avoid release to the environment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P501:Dispose of contents/container to ... P272:Contaminated work clothing should not be allowed out of the workplace. P362+P364:Take off contaminated clothing and wash it before reuse. P332+P313:IF SKIN irritation occurs: Get medical advice/attention. |
WGK Germany | 3 |
RTECS | ME8430000 |
Reaxy-Rn | 3909606 |
Class | 9 |
1. Zhang Q et al.. (2016) Inhibition of cytoskeletal protein carbonylation may protect against oxidative damage in traumatic brain injury.. Exp Ther Med, 12 (6): (4107-4112). [PMID:28101189] |
2. Skinner SC et al.. (2018) Increased Prevalence of Type 2 Diabetes-Related Complications in Combined Type 2 Diabetes and Sickle Cell Trait.. Diabetes Care, 41 (12): (2595-2602). [PMID:30327363] |