Natural antiproliferative and apoptotic compound. Inhibits iNOS expression and TGF-β/Smad pathway in bleomycin-induced pulmonary fibrosis. Antitumor, antiviral and anti-arrhythmia agent. Active in vivo and in vitro .
Storage Temp
Store at 2-8°C
Shipped In
Wet ice
Grade
analytical standard
Note
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description
Alkaloid isolated from Sophora flavescens. Antifribotic. Neuroprotective.
1.Chen He, Wenjing Wang, Guoli Wei, Yuqing Wang, Yingjie Wei, Jing Wang, Zhenhai Zhang. (2023) Sodium alginate combined with oxymatrine ameliorates CCl4-induced chemical hepatic fibrosis in mice. INTERNATIONAL IMMUNOPHARMACOLOGY, 125 (111144). [PMID:37922569][10.1016/j.intimp.2023.111144]
2.Fa-Li Zhang, Liu Yang, Wei-Hao He, Ling-Jun Xie, Fei Yang, Ying-Hui Wang, Ai-Guo Huang. (2023) In vivo antibacterial activity of medicinal plant Sophora flavescens against Streptococcus agalactiae infection. JOURNAL OF FISH DISEASES, 46 (9):(977-986). [PMID:37294673][10.1111/jfd.13818]
3.Shengwei Li, Guangqing Feng, Min Zhang, Xing Zhang, Jihong Lu, Chenyahui Feng, Fangshi Zhu. (2022) Oxymatrine attenuates TNBS-induced colinutis in rats through TLR9/Myd88/NF-κB signal pathway. HUMAN & EXPERIMENTAL TOXICOLOGY, [PMID:35290143][10.1177/09603271221078866]
4.Jin Yinshan, Liu Jiannan, Liu Yadong, Liu Yang, Guo Guiying, Yu Shiliang, An Ruihua. (2020) Oxymatrine Inhibits Renal Cell Carcinoma Progression by Suppressing β-Catenin Expression. Frontiers in Pharmacology, 11 (808). [PMID:32581789][10.3389/fphar.2020.00808]
5.Yu-Mei Zhao, Lv-Huan Wang, Si-Fan Luo, Qi-Qin Wang, Ruin Moaddel, Ting-Ting Zhang, Zheng-Jin Jiang. (2018) Magnetic beads-based neuraminidase enzyme microreactor as a drug discovery tool for screening inhibitors from compound libraries and fishing ligands from natural products. JOURNAL OF CHROMATOGRAPHY A, 1568 (123). [PMID:30005943][10.1016/j.chroma.2018.07.031]
6.Liyun Ma,Si-Min Liu,Lin Yao,Li Xu. (2014-12-22) Preparation and chromatographic performance evaluation of cucurbit[7]uril immobilized silica.. Journal of chromatography. A, 1376 (64-73). [PMID:25528071]
References
1.Chen He, Wenjing Wang, Guoli Wei, Yuqing Wang, Yingjie Wei, Jing Wang, Zhenhai Zhang. (2023) Sodium alginate combined with oxymatrine ameliorates CCl4-induced chemical hepatic fibrosis in mice. INTERNATIONAL IMMUNOPHARMACOLOGY, 125 (111144). [PMID:37922569][10.1016/j.intimp.2023.111144]
2.Fa-Li Zhang, Liu Yang, Wei-Hao He, Ling-Jun Xie, Fei Yang, Ying-Hui Wang, Ai-Guo Huang. (2023) In vivo antibacterial activity of medicinal plant Sophora flavescens against Streptococcus agalactiae infection. JOURNAL OF FISH DISEASES, 46 (9):(977-986). [PMID:37294673][10.1111/jfd.13818]
3.Shengwei Li, Guangqing Feng, Min Zhang, Xing Zhang, Jihong Lu, Chenyahui Feng, Fangshi Zhu. (2022) Oxymatrine attenuates TNBS-induced colinutis in rats through TLR9/Myd88/NF-κB signal pathway. HUMAN & EXPERIMENTAL TOXICOLOGY, [PMID:35290143][10.1177/09603271221078866]
4.Jin Yinshan, Liu Jiannan, Liu Yadong, Liu Yang, Guo Guiying, Yu Shiliang, An Ruihua. (2020) Oxymatrine Inhibits Renal Cell Carcinoma Progression by Suppressing β-Catenin Expression. Frontiers in Pharmacology, 11 (808). [PMID:32581789][10.3389/fphar.2020.00808]
5.Yu-Mei Zhao, Lv-Huan Wang, Si-Fan Luo, Qi-Qin Wang, Ruin Moaddel, Ting-Ting Zhang, Zheng-Jin Jiang. (2018) Magnetic beads-based neuraminidase enzyme microreactor as a drug discovery tool for screening inhibitors from compound libraries and fishing ligands from natural products. JOURNAL OF CHROMATOGRAPHY A, 1568 (123). [PMID:30005943][10.1016/j.chroma.2018.07.031]
6.Liyun Ma,Si-Min Liu,Lin Yao,Li Xu. (2014-12-22) Preparation and chromatographic performance evaluation of cucurbit[7]uril immobilized silica.. Journal of chromatography. A, 1376 (64-73). [PMID:25528071]
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D2401047