Grouped product items

SKU

Size

Availability

Price

Qty

A111286-100mg

100mg

Available within 4-8 weeks(?)

$70.90

A111286-500mg

500mg

Available within 4-8 weeks(?)

$153.90

A111286-1g

Available within 4-8 weeks(?)

$212.90

A111286-5g

Available within 8-12 weeks(?)

$958.90

A111286-25g

25g

Available within 4-8 weeks(?)

$4,313.90

Basic Description

Synonyms	Pachycarpidine \| BDBM50597716 \| Oxymatrine \| BBL030371 \| MLS001215101 \| rel-(41S,7aS,13aR,13bR)-10-Oxohexadecahydrodipyrido[2,1-f:3',2',1'-ij][1,6]naphthyridine 4-oxide \| Matrine 1beta-oxide \| Ammothamnine \| SCHEMBL13394285 \| Oxysophoridine \| DTXSID409374
Specifications & Purity	≥98%(HPLC)
Storage Temp	Store at 2-8°C
Shipped In	Wet ice
Product Description	Alkaloid isolated from Sophora flavescens. Antifribotic.

Associated Targets(Human)

MAOA Tclin Monoamine oxidase A (11911 Activities)

Discover Target: MAOA

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

HepG2 (196354 Activities)

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GNAS Tbio Guanine nucleotide-binding protein G(s), subunit alpha (103405 Activities)

Discover Target: GNAS

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CBX1 Tbio Chromobox protein homolog 1 (92434 Activities)

Discover Target: CBX1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Associated Targets(non-human)

Hdac6 Histone deacetylase 6 (222 Activities)

Discover Target: Hdac6

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Pkm Pyruvate kinase isozymes M1/M2 (66 Activities)

Discover Target: Pkm

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Plasmodium falciparum (966862 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mus musculus (284745 Activities)

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Hepatitis B virus (7925 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Coxsackievirus B3 (1096 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Influenza A virus (11224 Activities)

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Enterovirus A71 (1246 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

MDCK (10148 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Blood (6 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Tgfbr1 TGF-beta receptor type-1 (52 Activities)

Discover Target: Tgfbr1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mechanisms of Action

Mechanism of Action	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	References

Names and Identifiers

IUPAC Name	(1R,2R,9S,17S)-13-oxido-7-aza-13-azoniatetracyclo[7.7.1.02,7.013,17]heptadecan-6-one
INCHI	InChI=1S/C15H24N2O2/c18-14-7-1-6-13-12-5-3-9-17(19)8-2-4-11(15(12)17)10-16(13)14/h11-13,15H,1-10H2/t11-,12+,13+,15-,17?/m0/s1
InChi Key	XVPBINOPNYFXID-LHDUFFHYSA-N
Canonical SMILES	C1CC2C3CCC[N+]4(C3C(CCC4)CN2C(=O)C1)[O-]
Isomeric SMILES	C1C[C@@H]2[C@H]3CCC[N+]4([C@H]3[C@@H](CCC4)CN2C(=O)C1)[O-]
PubChem CID	114850
Molecular Weight	264.36

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Find and download the COA for your product by matching the lot number on the packaging.

7 results found

Lot Number	Certificate Type	Date	Item
K1808056	Certificate of Analysis	Sep 13, 2022	A111286
K1808055	Certificate of Analysis	Sep 13, 2022	A111286
A2303329	Certificate of Analysis	Sep 19, 2021	A111286
G2415309	Certificate of Analysis	Sep 19, 2021	A111286
H2315326	Certificate of Analysis	Sep 19, 2021	A111286
J2310171	Certificate of Analysis	Sep 19, 2021	A111286
L2305122	Certificate of Analysis	Sep 19, 2021	A111286

Safety and Hazards(GHS)

Pictogram(s)	GHS07
Signal	Warning
Hazard Statements	H302:Harmful if swallowed
Precautionary Statements	P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P270:Do not eat, drink or smoke when using this product. P330:Rinse mouth. P301+P317:IF SWALLOWED: Get medical help.

Citations of This Product

How to Cite Aladdin Scientific Products?

1. Chen He, Wenjing Wang, Guoli Wei, Yuqing Wang, Yingjie Wei, Jing Wang, Zhenhai Zhang. (2023) Sodium alginate combined with oxymatrine ameliorates CCl4-induced chemical hepatic fibrosis in mice. INTERNATIONAL IMMUNOPHARMACOLOGY, 125 (111144). [PMID:37922569] [10.1016/j.intimp.2023.111144]
2. Fa-Li Zhang, Liu Yang, Wei-Hao He, Ling-Jun Xie, Fei Yang, Ying-Hui Wang, Ai-Guo Huang. (2023) In vivo antibacterial activity of medicinal plant Sophora flavescens against Streptococcus agalactiae infection. JOURNAL OF FISH DISEASES, 46 (9): (977-986). [PMID:37294673] [10.1111/jfd.13818]
3. Shengwei Li, Guangqing Feng, Min Zhang, Xing Zhang, Jihong Lu, Chenyahui Feng, Fangshi Zhu. (2022) Oxymatrine attenuates TNBS-induced colinutis in rats through TLR9/Myd88/NF-κB signal pathway. HUMAN & EXPERIMENTAL TOXICOLOGY, [PMID:35290143] [10.1177/09603271221078866]
4. Jin Yinshan, Liu Jiannan, Liu Yadong, Liu Yang, Guo Guiying, Yu Shiliang, An Ruihua. (2020) Oxymatrine Inhibits Renal Cell Carcinoma Progression by Suppressing β-Catenin Expression. Frontiers in Pharmacology, 11 (808). [PMID:32581789] [10.3389/fphar.2020.00808]
5. Yu-Mei Zhao, Lv-Huan Wang, Si-Fan Luo, Qi-Qin Wang, Ruin Moaddel, Ting-Ting Zhang, Zheng-Jin Jiang. (2018) Magnetic beads-based neuraminidase enzyme microreactor as a drug discovery tool for screening inhibitors from compound libraries and fishing ligands from natural products. JOURNAL OF CHROMATOGRAPHY A, 1568 (123). [PMID:30005943] [10.1016/j.chroma.2018.07.031]
6. Liyun Ma,Si-Min Liu,Lin Yao,Li Xu. (2014-12-22) Preparation and chromatographic performance evaluation of cucurbit[7]uril immobilized silica.. Journal of chromatography. A, 1376 (64-73). [PMID:25528071]

References

1. Chen He, Wenjing Wang, Guoli Wei, Yuqing Wang, Yingjie Wei, Jing Wang, Zhenhai Zhang. (2023) Sodium alginate combined with oxymatrine ameliorates CCl4-induced chemical hepatic fibrosis in mice. INTERNATIONAL IMMUNOPHARMACOLOGY, 125 (111144). [PMID:37922569] [10.1016/j.intimp.2023.111144]
2. Fa-Li Zhang, Liu Yang, Wei-Hao He, Ling-Jun Xie, Fei Yang, Ying-Hui Wang, Ai-Guo Huang. (2023) In vivo antibacterial activity of medicinal plant Sophora flavescens against Streptococcus agalactiae infection. JOURNAL OF FISH DISEASES, 46 (9): (977-986). [PMID:37294673] [10.1111/jfd.13818]
3. Shengwei Li, Guangqing Feng, Min Zhang, Xing Zhang, Jihong Lu, Chenyahui Feng, Fangshi Zhu. (2022) Oxymatrine attenuates TNBS-induced colinutis in rats through TLR9/Myd88/NF-κB signal pathway. HUMAN & EXPERIMENTAL TOXICOLOGY, [PMID:35290143] [10.1177/09603271221078866]
4. Jin Yinshan, Liu Jiannan, Liu Yadong, Liu Yang, Guo Guiying, Yu Shiliang, An Ruihua. (2020) Oxymatrine Inhibits Renal Cell Carcinoma Progression by Suppressing β-Catenin Expression. Frontiers in Pharmacology, 11 (808). [PMID:32581789] [10.3389/fphar.2020.00808]
5. Yu-Mei Zhao, Lv-Huan Wang, Si-Fan Luo, Qi-Qin Wang, Ruin Moaddel, Ting-Ting Zhang, Zheng-Jin Jiang. (2018) Magnetic beads-based neuraminidase enzyme microreactor as a drug discovery tool for screening inhibitors from compound libraries and fishing ligands from natural products. JOURNAL OF CHROMATOGRAPHY A, 1568 (123). [PMID:30005943] [10.1016/j.chroma.2018.07.031]
6. Liyun Ma,Si-Min Liu,Lin Yao,Li Xu. (2014-12-22) Preparation and chromatographic performance evaluation of cucurbit[7]uril immobilized silica.. Journal of chromatography. A, 1376 (64-73). [PMID:25528071]

Solution Calculators

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Ammothamnine - ≥98% (HPLC), high purity , CAS No.16837-52-8

Basic Description

Associated Targets(Human)

Associated Targets(non-human)

Mechanisms of Action

Names and Identifiers

Certificates

Certificate of Analysis(COA)

Safety and Hazards(GHS)

Related Documents

Citations of This Product

References

Solution Calculators

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

SKU	Size	Availability	Price
A111286-100mg	100mg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$70.90
A111286-500mg	500mg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$153.90
A111286-1g	1g	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$212.90
A111286-5g	5g	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$958.90
A111286-25g	25g	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$4,313.90