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Ampicillin Na - USP grade, high purity , CAS No.69-52-3

11 Citations

PharmPure™

USP

CAS#: 69-52-3
Formula: C₁₆H₁₈N₃NaO₄S
Molecular Weight: 371.39
MDL number: MFCD00064313
PubChem CID: 23663979
PubChem SID: 488200395

Item Number

A105483

Grouped product items
SKU	Size	Availability	Price
A105483-5g	5g	In stock	$17.90
A105483-25g	25g	In stock	$54.90
A105483-100g	100g	In stock	$180.90
A105483-500g	500g	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$653.90

β-lactam antibiotic agent

Basic Description

Synonyms	200-708-1 \| 69-52-3 \| Ampicillin sodium \| Ampicillin sodium salt \| Sodium ampicillin \| Citteral \| Domicillin \| Penialmen \| Ampicillin natrium \| Ampicillin (sodium) \| Binotal sodium \| Sodium binotal \| Totacillin-N \| Penbritin-S \| Principen/N \| Omnipen-N \| Amcill-S \| Alpen-N \| Penbritin \| Totac
Specifications & Purity	PharmPure™, USP
Biochemical and Physiological Mechanisms	Mode of Action: This is a β-lactam antibiotic that inhibits bacterial cell-wall synthesis by inactivating transpeptidases on the inner surface of the bacterial cell membrane. Mode of Resistance: Administration with β-lactamase cleaves the β-lactam ring o
Storage Temp	Store at 2-8°C
Shipped In	Wet ice
Grade	PharmPure™, USP
Note	Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description	Ampicillin is reported as slightly soluble in water, practically insoluble in alcohol, chloroform, ether and fixed oils but soluble in dilute acids or bases. The solution should not be autoclaved; a stock solution should be sterilized through filtration and stored frozen, where it will be stable for months. Used to select for ampicillin resistance in mutated and transformed cells.

Associated Targets(Human)

POLB Tchem DNA polymerase beta (23632 Activities)

Discover Target: POLB

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

GLA Tclin Alpha-galactosidase A (5444 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CYP3A4 Tclin Cytochrome P450 3A4 (53859 Activities)

Discover Target: CYP3A4

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

HSD17B10 Tchem Endoplasmic reticulum-associated amyloid beta-peptide-binding protein (20669 Activities)

Discover Target: HSD17B10

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

POLK Tbio DNA polymerase kappa (8653 Activities)

Discover Target: POLK

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

POLI Tchem DNA polymerase iota (116820 Activities)

Discover Target: POLI

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

POLH Tchem DNA polymerase eta (21678 Activities)

Discover Target: POLH

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APEX1 Tchem DNA-(apurinic or apyrimidinic site) lyase (38016 Activities)

Discover Target: APEX1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 (345557 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

KDM4E Tchem Lysine-specific demethylase 4D-like (40243 Activities)

Discover Target: KDM4E

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

RECQL Tbio ATP-dependent DNA helicase Q1 (5575 Activities)

Discover Target: RECQL

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

BLM Tchem Bloom syndrome protein (4248 Activities)

Discover Target: BLM

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

GMNN Tbio Geminin (128009 Activities)

Discover Target: GMNN

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SLCO1B1 Tchem Solute carrier organic anion transporter family member 1B1 (2672 Activities)

Discover Target: SLCO1B1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SLCO1B3 Tchem Solute carrier organic anion transporter family member 1B3 (2517 Activities)

Discover Target: SLCO1B3

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USP1 Tchem Ubiquitin carboxyl-terminal hydrolase 1 (22556 Activities)

Discover Target: USP1

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RUNX1 Tbio Runt-related transcription factor 1/Core-binding factor subunit beta (7867 Activities)

Discover Target: RUNX1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

GLS Tchem Glutaminase kidney isoform, mitochondrial (16997 Activities)

Discover Target: GLS

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Associated Targets(non-human)

ampC Beta-lactamase AmpC (62480 Activities)

Discover Target: ampC

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Cruzipain (33337 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ftsZ Cell division protein ftsZ (97 Activities)

Discover Target: ftsZ

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Streptococcus pneumoniae (31063 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Pseudomonas aeruginosa (123386 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Ralstonia solanacearum (520 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Staphylococcus aureus (210822 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Escherichia coli (133304 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Bacillus subtilis (32866 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Bacillus cereus (7522 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

rep Replicase polyprotein 1ab (378 Activities)

Discover Target: rep

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

fba Putative fructose-1,6-bisphosphate aldolase (15559 Activities)

Discover Target: fba

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CCT2 T-complex protein 1 subunit beta (5007 Activities)

Discover Target: CCT2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SARS-CoV-2 (38078 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Names and Identifiers

Pubchem Sid	488200395
Pubchem Sid Url	https://pubchem.ncbi.nlm.nih.gov/substance/488200395
IUPAC Name	sodium;(2S,5R,6R)-6-[[(2R)-2-amino-2-phenylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate
INCHI	InChI=1S/C16H19N3O4S.Na/c1-16(2)11(15(22)23)19-13(21)10(14(19)24-16)18-12(20)9(17)8-6-4-3-5-7-8;/h3-7,9-11,14H,17H2,1-2H3,(H,18,20)(H,22,23);/q;+1/p-1/t9-,10-,11+,14-;/m1./s1
InChi Key	KLOHDWPABZXLGI-YWUHCJSESA-M
Canonical SMILES	CC1(C(N2C(S1)C(C2=O)NC(=O)C(C3=CC=CC=C3)N)C(=O)[O-])C.[Na+]
Isomeric SMILES	CC1([C@@H](N2[C@H](S1)[C@@H](C2=O)NC(=O)[C@@H](C3=CC=CC=C3)N)C(=O)[O-])C.[Na+]
PubChem CID	23663979
Molecular Weight	371.39

Certificates

Certificate of Analysis(COA)

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24 results found

Lot Number	Certificate Type	Date	Item
C2408167	Certificate of Analysis	Jul 27, 2023	A105483
J2318199	Certificate of Analysis	Jul 27, 2023	A105483
J2318198	Certificate of Analysis	Jul 27, 2023	A105483
J2318042	Certificate of Analysis	Jul 27, 2023	A105483
C2325043	Certificate of Analysis	Jan 12, 2023	A105483
C2325044	Certificate of Analysis	Jan 12, 2023	A105483
C2325045	Certificate of Analysis	Jan 12, 2023	A105483
C2325046	Certificate of Analysis	Jan 12, 2023	A105483
C2325047	Certificate of Analysis	Jan 12, 2023	A105483
C2325048	Certificate of Analysis	Jan 12, 2023	A105483
C2325049	Certificate of Analysis	Jan 12, 2023	A105483
K2209097	Certificate of Analysis	Sep 12, 2022	A105483
K2209082	Certificate of Analysis	Sep 12, 2022	A105483
K2209078	Certificate of Analysis	Sep 12, 2022	A105483
G2204051	Certificate of Analysis	Jul 07, 2022	A105483
G2204052	Certificate of Analysis	Jul 07, 2022	A105483
F2221227	Certificate of Analysis	Jul 01, 2022	A105483
H2212093	Certificate of Analysis	Jun 22, 2022	A105483
H2212096	Certificate of Analysis	Jun 22, 2022	A105483
H2212404	Certificate of Analysis	Jun 22, 2022	A105483
H2212067	Certificate of Analysis	Jun 22, 2022	A105483
E2205002	Certificate of Analysis	May 10, 2022	A105483
A2408071	Certificate of Analysis	Apr 02, 2022	A105483
C2223065	Certificate of Analysis	Mar 26, 2022	A105483

Chemical and Physical Properties

Solubility	Freely soluble in water. Sparingly soluble in acetone
Sensitivity	Moisture sensitive.
Melt Point(°C)	215°C

Safety and Hazards(GHS)

Pictogram(s)	GHS08
Signal	Danger
Hazard Statements	H317:May cause an allergic skin reaction H334:May cause allergy or asthma symptoms or breathing difficulties if inhaled
Precautionary Statements	P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P501:Dispose of contents/container to ... P284:[In case of inadequate ventilation] Wear respiratory protection. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P272:Contaminated work clothing should not be allowed out of the workplace. P333+P313:IF SKIN irritation or rash occurs: Get medical advice/attention. P362+P364:Take off contaminated clothing and wash it before reuse. P342+P316:If experiencing respiratory symptoms: Get emergence medical help immediately.

Alternative Products

Citations of This Product

1. Zhu Yongbo, Huang Lijun, Liang Meng, Zhang Zuokun, Xie Hao, Sheng Xingxin, Li Xinyi, Zhong Ming, Zhou Binbin. (2023) Green synthesis of plate-shaped CuONPs using Macleaya cordata (Wild.) R.BR extracts for photocatalytic degradation and antibacterial properties. Biomass Conversion and Biorefinery, (15): (1-13). [PMID:14583450]
2. Jiao Wei, Zongmei Zheng, Xinxin Hou, Fengjing Jia, Yuan Yuan, Fuwen Yuan, Feng He, Liang Hu, Ling Zhao. (2024) Echinacoside inhibits colorectal cancer metastasis via modulating the gut microbiota and suppressing the PI3K/AKT signaling pathway. JOURNAL OF ETHNOPHARMACOLOGY, 318 (116866). [PMID:37429503]
3. Zhang Yuntao, Liu Lin, Wei Chunbo, Wang Xuanyang, Li Ran, Xu Xiaoqing, Zhang Yingfeng, Geng Guannan, Dang Keke, Ming Zhu, Tao Xinmiao, Xu Huan, Yan Xuemin, Zhang Jia, Hu Jinxia, Li Ying. (2023) Vitamin K2 supplementation improves impaired glycemic homeostasis and insulin sensitivity for type 2 diabetes through gut microbiome and fecal metabolites. BMC Medicine, 21 (1): (1-16). [PMID:37147641]
4. Fujian Qin, Jiankang Li, Tianxiao Mao, Shuo Feng, Jing Li, Maode Lai. (2023) 2 Hydroxybutyric Acid-Producing Bacteria in Gut Microbiome and Fusobacterium nucleatum Regulates 2 Hydroxybutyric Acid Level In Vivo. Metabolites, 13 (3): (451). [PMID:36984891]
5. Zhang Haotian, Wang Xiaohong, Xu Zuhui, Ma Jimei, Li Zi-Long, Cheng Wan-Min, Jiang Hong. (2023) A caprylate esterase–activated fluorescent probe for sensitive and selective detection of Salmonella enteritidis. ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 415 (12): (2163-2172). [PMID:36869898]
6. Yajie Cai, Xiaojiaoyang Li, Qi Han, Jinzhao Bai, Qi Zheng, Rong Sun, Runping Liu. (2023) Si–Ni-San improves experimental colitis by favoring Akkermensia colonization. JOURNAL OF ETHNOPHARMACOLOGY, 305 (116067). [PMID:36586523]
7. Zhen-Ping Zou, Yue Du, Ting-Ting Fang, Ying Zhou, Bang-Ce Ye. (2023) Biomarker-responsive engineered probiotic diagnoses, records, and ameliorates inflammatory bowel disease in mice. Cell Host & Microbe, 31 (199-212.e5). [PMID:36758520]
8. Qianqian Yao, Linlin Fan, Nan Zheng, Christophe Blecker, Véronique Delcenserie, Huiying Li, Jiaqi Wang. (2022) 2′-Fucosyllactose Ameliorates Inflammatory Bowel Disease by Modulating Gut Microbiota and Promoting MUC2 Expression. Frontiers in Nutrition, 9 (822020). [PMID:35252301]
9. Xiuxiu Yang, Zhongqiang Yang. (2022) Simple and Rapid Detection of Ibuprofen─A Typical Pharmaceuticals and Personal Care Products─by a Liquid Crystal Aptasensor. LANGMUIR, 38 (1): (282–288). [PMID:34955019]
10. Zhiwei Qie,Jialei Bai,Bin Xie,Lin Yuan,Nan Song,Yuan Peng,Xianjun Fan,Huanying Zhou,Fengchun Chen,Shuang Li,Baoan Ning,Zhixian Gao. (2015-06-11) Sensitive detection of atrazine in tap water using TELISA.. The Analyst, 140 ((15)): (5220-5226). [PMID:26061585]
11. Jingyi Hu,Hai Huang,Yuan Che,Chujie Ding,Lu Zhang,Yun Wang,Haiping Hao,Hong Shen,Lijuan Cao. (2020-09-18) Qingchang Huashi Formula attenuates DSS-induced colitis in mice by restoring gut microbiota-metabolism homeostasis and goblet cell function.. Journal of ethnopharmacology, 266 (113394-113394). [PMID:32941971]

References

1. Zhu Yongbo, Huang Lijun, Liang Meng, Zhang Zuokun, Xie Hao, Sheng Xingxin, Li Xinyi, Zhong Ming, Zhou Binbin. (2023) Green synthesis of plate-shaped CuONPs using Macleaya cordata (Wild.) R.BR extracts for photocatalytic degradation and antibacterial properties. Biomass Conversion and Biorefinery, (15): (1-13). [PMID:14583450]
2. Jiao Wei, Zongmei Zheng, Xinxin Hou, Fengjing Jia, Yuan Yuan, Fuwen Yuan, Feng He, Liang Hu, Ling Zhao. (2024) Echinacoside inhibits colorectal cancer metastasis via modulating the gut microbiota and suppressing the PI3K/AKT signaling pathway. JOURNAL OF ETHNOPHARMACOLOGY, 318 (116866). [PMID:37429503]
3. Zhang Yuntao, Liu Lin, Wei Chunbo, Wang Xuanyang, Li Ran, Xu Xiaoqing, Zhang Yingfeng, Geng Guannan, Dang Keke, Ming Zhu, Tao Xinmiao, Xu Huan, Yan Xuemin, Zhang Jia, Hu Jinxia, Li Ying. (2023) Vitamin K2 supplementation improves impaired glycemic homeostasis and insulin sensitivity for type 2 diabetes through gut microbiome and fecal metabolites. BMC Medicine, 21 (1): (1-16). [PMID:37147641]
4. Fujian Qin, Jiankang Li, Tianxiao Mao, Shuo Feng, Jing Li, Maode Lai. (2023) 2 Hydroxybutyric Acid-Producing Bacteria in Gut Microbiome and Fusobacterium nucleatum Regulates 2 Hydroxybutyric Acid Level In Vivo. Metabolites, 13 (3): (451). [PMID:36984891]
5. Zhang Haotian, Wang Xiaohong, Xu Zuhui, Ma Jimei, Li Zi-Long, Cheng Wan-Min, Jiang Hong. (2023) A caprylate esterase–activated fluorescent probe for sensitive and selective detection of Salmonella enteritidis. ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 415 (12): (2163-2172). [PMID:36869898]
6. Yajie Cai, Xiaojiaoyang Li, Qi Han, Jinzhao Bai, Qi Zheng, Rong Sun, Runping Liu. (2023) Si–Ni-San improves experimental colitis by favoring Akkermensia colonization. JOURNAL OF ETHNOPHARMACOLOGY, 305 (116067). [PMID:36586523]
7. Zhen-Ping Zou, Yue Du, Ting-Ting Fang, Ying Zhou, Bang-Ce Ye. (2023) Biomarker-responsive engineered probiotic diagnoses, records, and ameliorates inflammatory bowel disease in mice. Cell Host & Microbe, 31 (199-212.e5). [PMID:36758520]
8. Qianqian Yao, Linlin Fan, Nan Zheng, Christophe Blecker, Véronique Delcenserie, Huiying Li, Jiaqi Wang. (2022) 2′-Fucosyllactose Ameliorates Inflammatory Bowel Disease by Modulating Gut Microbiota and Promoting MUC2 Expression. Frontiers in Nutrition, 9 (822020). [PMID:35252301]
9. Xiuxiu Yang, Zhongqiang Yang. (2022) Simple and Rapid Detection of Ibuprofen─A Typical Pharmaceuticals and Personal Care Products─by a Liquid Crystal Aptasensor. LANGMUIR, 38 (1): (282–288). [PMID:34955019]
10. Zhiwei Qie,Jialei Bai,Bin Xie,Lin Yuan,Nan Song,Yuan Peng,Xianjun Fan,Huanying Zhou,Fengchun Chen,Shuang Li,Baoan Ning,Zhixian Gao. (2015-06-11) Sensitive detection of atrazine in tap water using TELISA.. The Analyst, 140 ((15)): (5220-5226). [PMID:26061585]
11. Jingyi Hu,Hai Huang,Yuan Che,Chujie Ding,Lu Zhang,Yun Wang,Haiping Hao,Hong Shen,Lijuan Cao. (2020-09-18) Qingchang Huashi Formula attenuates DSS-induced colitis in mice by restoring gut microbiota-metabolism homeostasis and goblet cell function.. Journal of ethnopharmacology, 266 (113394-113394). [PMID:32941971]

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