Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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SKU | Size | Availability | Price | Qty |
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A105483-5g | 5g | In stock | $17.90 | |
A105483-25g | 25g | In stock | $54.90 | |
A105483-100g | 100g | In stock | $180.90 | |
A105483-500g | 500g | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $653.90 |
β-lactam antibiotic agent
Synonyms | AMPICILLIN SODIUM (USP MONOGRAPH) | sodium (2S,5R,6R)-6-{[(2R)-2-amino-2-phenylacetyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate | A836527 | Ampicillin (as sodium) | AMPICILLIN SODIUM [GREEN BOOK] | D-(-)-alpha-Aminobenzylpe |
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Specifications & Purity | PharmPure™, USP |
Biochemical and Physiological Mechanisms | Mode of Action: This is a β-lactam antibiotic that inhibits bacterial cell-wall synthesis by inactivating transpeptidases on the inner surface of the bacterial cell membrane. Mode of Resistance: Administration with β-lactamase cleaves the β-lactam ring o |
Storage Temp | Store at 2-8°C |
Shipped In | Wet ice |
Grade | PharmPure™, USP |
Note | Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details. |
Product Description | Ampicillin is reported as slightly soluble in water, practically insoluble in alcohol, chloroform, ether and fixed oils but soluble in dilute acids or bases. The solution should not be autoclaved; a stock solution should be sterilized through filtration and stored frozen, where it will be stable for months. |
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Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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Pubchem Sid | 488200395 |
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Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/488200395 |
IUPAC Name | sodium;(2S,5R,6R)-6-[[(2R)-2-amino-2-phenylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate |
INCHI | InChI=1S/C16H19N3O4S.Na/c1-16(2)11(15(22)23)19-13(21)10(14(19)24-16)18-12(20)9(17)8-6-4-3-5-7-8;/h3-7,9-11,14H,17H2,1-2H3,(H,18,20)(H,22,23);/q;+1/p-1/t9-,10-,11+,14-;/m1./s1 |
InChi Key | KLOHDWPABZXLGI-YWUHCJSESA-M |
Canonical SMILES | CC1(C(N2C(S1)C(C2=O)NC(=O)C(C3=CC=CC=C3)N)C(=O)[O-])C.[Na+] |
Isomeric SMILES | CC1([C@@H](N2[C@H](S1)[C@@H](C2=O)NC(=O)[C@@H](C3=CC=CC=C3)N)C(=O)[O-])C.[Na+] |
PubChem CID | 23663979 |
Molecular Weight | 371.39 |
Enter Lot Number to search for COA:
Find and download the COA for your product by matching the lot number on the packaging.
Lot Number | Certificate Type | Date | Item |
---|---|---|---|
K2413165 | Certificate of Analysis | Oct 21, 2024 | A105483 |
K2413153 | Certificate of Analysis | Oct 21, 2024 | A105483 |
K2413155 | Certificate of Analysis | Oct 21, 2024 | A105483 |
K2413156 | Certificate of Analysis | Oct 21, 2024 | A105483 |
I2426160 | Certificate of Analysis | Aug 21, 2024 | A105483 |
I2426159 | Certificate of Analysis | Aug 21, 2024 | A105483 |
I2426157 | Certificate of Analysis | Aug 21, 2024 | A105483 |
I2426158 | Certificate of Analysis | Aug 21, 2024 | A105483 |
C2408167 | Certificate of Analysis | Jul 27, 2023 | A105483 |
J2318199 | Certificate of Analysis | Jul 27, 2023 | A105483 |
J2318198 | Certificate of Analysis | Jul 27, 2023 | A105483 |
J2318042 | Certificate of Analysis | Jul 27, 2023 | A105483 |
C2325045 | Certificate of Analysis | Jan 12, 2023 | A105483 |
C2325046 | Certificate of Analysis | Jan 12, 2023 | A105483 |
C2325047 | Certificate of Analysis | Jan 12, 2023 | A105483 |
C2325048 | Certificate of Analysis | Jan 12, 2023 | A105483 |
C2325049 | Certificate of Analysis | Jan 12, 2023 | A105483 |
C2325044 | Certificate of Analysis | Jan 12, 2023 | A105483 |
C2325043 | Certificate of Analysis | Jan 12, 2023 | A105483 |
K2209078 | Certificate of Analysis | Sep 12, 2022 | A105483 |
K2209082 | Certificate of Analysis | Sep 12, 2022 | A105483 |
K2209097 | Certificate of Analysis | Sep 12, 2022 | A105483 |
G2204052 | Certificate of Analysis | Jul 07, 2022 | A105483 |
G2204051 | Certificate of Analysis | Jul 07, 2022 | A105483 |
F2221227 | Certificate of Analysis | Jul 01, 2022 | A105483 |
H2212096 | Certificate of Analysis | Jun 22, 2022 | A105483 |
H2212404 | Certificate of Analysis | Jun 22, 2022 | A105483 |
H2212093 | Certificate of Analysis | Jun 22, 2022 | A105483 |
H2212067 | Certificate of Analysis | Jun 22, 2022 | A105483 |
E2205002 | Certificate of Analysis | May 10, 2022 | A105483 |
A2408071 | Certificate of Analysis | Apr 02, 2022 | A105483 |
C2223065 | Certificate of Analysis | Mar 26, 2022 | A105483 |
Solubility | Freely soluble in water. Sparingly soluble in acetone |
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Sensitivity | Moisture sensitive. |
Melt Point(°C) | 215°C |
Pictogram(s) | GHS08 |
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Signal | Danger |
Hazard Statements | H317:May cause an allergic skin reaction H334:May cause allergy or asthma symptoms or breathing difficulties if inhaled |
Precautionary Statements | P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P501:Dispose of contents/container to ... P284:[In case of inadequate ventilation] Wear respiratory protection. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P272:Contaminated work clothing should not be allowed out of the workplace. P333+P313:IF SKIN irritation or rash occurs: Get medical advice/attention. P362+P364:Take off contaminated clothing and wash it before reuse. P342+P316:If experiencing respiratory symptoms: Get emergence medical help immediately. |
Starting at $46.90
1. Zhu Yongbo, Huang Lijun, Liang Meng, Zhang Zuokun, Xie Hao, Sheng Xingxin, Li Xinyi, Zhong Ming, Zhou Binbin. (2023) Green synthesis of plate-shaped CuONPs using Macleaya cordata (Wild.) R.BR extracts for photocatalytic degradation and antibacterial properties. Biomass Conversion and Biorefinery, (15): (1-13). [PMID:14583450] [10.1007/s13399-023-04943-x] |
2. Jiao Wei, Zongmei Zheng, Xinxin Hou, Fengjing Jia, Yuan Yuan, Fuwen Yuan, Feng He, Liang Hu, Ling Zhao. (2024) Echinacoside inhibits colorectal cancer metastasis via modulating the gut microbiota and suppressing the PI3K/AKT signaling pathway. JOURNAL OF ETHNOPHARMACOLOGY, 318 (116866). [PMID:37429503] [10.1016/j.jep.2023.116866] |
3. Zhang Yuntao, Liu Lin, Wei Chunbo, Wang Xuanyang, Li Ran, Xu Xiaoqing, Zhang Yingfeng, Geng Guannan, Dang Keke, Ming Zhu, Tao Xinmiao, Xu Huan, Yan Xuemin, Zhang Jia, Hu Jinxia, Li Ying. (2023) Vitamin K2 supplementation improves impaired glycemic homeostasis and insulin sensitivity for type 2 diabetes through gut microbiome and fecal metabolites. BMC Medicine, 21 (1): (1-16). [PMID:37147641] [10.1186/s12916-023-02880-0] |
4. Fujian Qin, Jiankang Li, Tianxiao Mao, Shuo Feng, Jing Li, Maode Lai. (2023) 2 Hydroxybutyric Acid-Producing Bacteria in Gut Microbiome and Fusobacterium nucleatum Regulates 2 Hydroxybutyric Acid Level In Vivo. Metabolites, 13 (3): (451). [PMID:36984891] [10.3390/metabo13030451] |
5. Zhang Haotian, Wang Xiaohong, Xu Zuhui, Ma Jimei, Li Zi-Long, Cheng Wan-Min, Jiang Hong. (2023) A caprylate esterase–activated fluorescent probe for sensitive and selective detection of Salmonella enteritidis. ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 415 (12): (2163-2172). [PMID:36869898] [10.1007/s00216-023-04623-9] |
6. Yajie Cai, Xiaojiaoyang Li, Qi Han, Jinzhao Bai, Qi Zheng, Rong Sun, Runping Liu. (2023) Si–Ni-San improves experimental colitis by favoring Akkermensia colonization. JOURNAL OF ETHNOPHARMACOLOGY, 305 (116067). [PMID:36586523] [10.1016/j.jep.2022.116067] |
7. Zhen-Ping Zou, Yue Du, Ting-Ting Fang, Ying Zhou, Bang-Ce Ye. (2023) Biomarker-responsive engineered probiotic diagnoses, records, and ameliorates inflammatory bowel disease in mice. Cell Host & Microbe, 31 (199-212.e5). [PMID:36758520] [10.1016/j.chom.2022.12.004] |
8. Qianqian Yao, Linlin Fan, Nan Zheng, Christophe Blecker, Véronique Delcenserie, Huiying Li, Jiaqi Wang. (2022) 2′-Fucosyllactose Ameliorates Inflammatory Bowel Disease by Modulating Gut Microbiota and Promoting MUC2 Expression. Frontiers in Nutrition, 9 (822020). [PMID:35252301] [10.3389/fnut.2022.822020] |
9. Xiuxiu Yang, Zhongqiang Yang. (2022) Simple and Rapid Detection of Ibuprofen─A Typical Pharmaceuticals and Personal Care Products─by a Liquid Crystal Aptasensor. LANGMUIR, 38 (1): (282–288). [PMID:34955019] [10.1021/acs.langmuir.1c02480] |
10. Liu Yaqing, Lin Xiaodong, Ji Xiangyi, Hao Zhe, Tao Zhanhui. (2020) Smartphone-based enzyme-free fluorescence sensing of organophosphate DDVP. MICROCHIMICA ACTA, 187 (7): (1-8). [PMID:32613298] [10.1007/s00604-020-04384-7] |
11. Xu Chen, Yanan Liu, Ange Lin, Na Huang, Liquan Long, Ye Gang, Jie Liu. (2018) Folic acid-modified mesoporous silica nanoparticles with pH-responsiveness loaded with Amp for an enhanced effect against anti-drug-resistant bacteria by overcoming efflux pump systems. Biomaterials Science, 6 (7): (1923-1935). [PMID:29850668] [10.1039/C8BM00262B] |
12. Wang Jun, Ma Kui, Yin Huanshun, Zhou Yunlei, Ai Shiyun. (2018) Aptamer based voltammetric determination of ampicillin using a single-stranded DNA binding protein and DNA functionalized gold nanoparticles. MICROCHIMICA ACTA, 185 (1): (1-7). [PMID:29594557] [10.1007/s00604-017-2566-8] |
13. Shi Hong, Liu Xueqing, Zhang Yuanfang. (2014) Fabrication of novel antimicrobial poly(vinyl chloride) plastic for automobile interior applications. IRANIAN POLYMER JOURNAL, 23 (4): (297-305). [PMID:] [10.1007/s13726-014-0226-y] |
14. Zhiwei Qie,Jialei Bai,Bin Xie,Lin Yuan,Nan Song,Yuan Peng,Xianjun Fan,Huanying Zhou,Fengchun Chen,Shuang Li,Baoan Ning,Zhixian Gao. (2015-06-11) Sensitive detection of atrazine in tap water using TELISA.. The Analyst, 140 ((15)): (5220-5226). [PMID:26061585] |
15. Jingyi Hu,Hai Huang,Yuan Che,Chujie Ding,Lu Zhang,Yun Wang,Haiping Hao,Hong Shen,Lijuan Cao. (2020-09-18) Qingchang Huashi Formula attenuates DSS-induced colitis in mice by restoring gut microbiota-metabolism homeostasis and goblet cell function.. Journal of ethnopharmacology, 266 (113394-113394). [PMID:32941971] |
1. Zhu Yongbo, Huang Lijun, Liang Meng, Zhang Zuokun, Xie Hao, Sheng Xingxin, Li Xinyi, Zhong Ming, Zhou Binbin. (2023) Green synthesis of plate-shaped CuONPs using Macleaya cordata (Wild.) R.BR extracts for photocatalytic degradation and antibacterial properties. Biomass Conversion and Biorefinery, (15): (1-13). [PMID:14583450] [10.1007/s13399-023-04943-x] |
2. Jiao Wei, Zongmei Zheng, Xinxin Hou, Fengjing Jia, Yuan Yuan, Fuwen Yuan, Feng He, Liang Hu, Ling Zhao. (2024) Echinacoside inhibits colorectal cancer metastasis via modulating the gut microbiota and suppressing the PI3K/AKT signaling pathway. JOURNAL OF ETHNOPHARMACOLOGY, 318 (116866). [PMID:37429503] [10.1016/j.jep.2023.116866] |
3. Zhang Yuntao, Liu Lin, Wei Chunbo, Wang Xuanyang, Li Ran, Xu Xiaoqing, Zhang Yingfeng, Geng Guannan, Dang Keke, Ming Zhu, Tao Xinmiao, Xu Huan, Yan Xuemin, Zhang Jia, Hu Jinxia, Li Ying. (2023) Vitamin K2 supplementation improves impaired glycemic homeostasis and insulin sensitivity for type 2 diabetes through gut microbiome and fecal metabolites. BMC Medicine, 21 (1): (1-16). [PMID:37147641] [10.1186/s12916-023-02880-0] |
4. Fujian Qin, Jiankang Li, Tianxiao Mao, Shuo Feng, Jing Li, Maode Lai. (2023) 2 Hydroxybutyric Acid-Producing Bacteria in Gut Microbiome and Fusobacterium nucleatum Regulates 2 Hydroxybutyric Acid Level In Vivo. Metabolites, 13 (3): (451). [PMID:36984891] [10.3390/metabo13030451] |
5. Zhang Haotian, Wang Xiaohong, Xu Zuhui, Ma Jimei, Li Zi-Long, Cheng Wan-Min, Jiang Hong. (2023) A caprylate esterase–activated fluorescent probe for sensitive and selective detection of Salmonella enteritidis. ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 415 (12): (2163-2172). [PMID:36869898] [10.1007/s00216-023-04623-9] |
6. Yajie Cai, Xiaojiaoyang Li, Qi Han, Jinzhao Bai, Qi Zheng, Rong Sun, Runping Liu. (2023) Si–Ni-San improves experimental colitis by favoring Akkermensia colonization. JOURNAL OF ETHNOPHARMACOLOGY, 305 (116067). [PMID:36586523] [10.1016/j.jep.2022.116067] |
7. Zhen-Ping Zou, Yue Du, Ting-Ting Fang, Ying Zhou, Bang-Ce Ye. (2023) Biomarker-responsive engineered probiotic diagnoses, records, and ameliorates inflammatory bowel disease in mice. Cell Host & Microbe, 31 (199-212.e5). [PMID:36758520] [10.1016/j.chom.2022.12.004] |
8. Qianqian Yao, Linlin Fan, Nan Zheng, Christophe Blecker, Véronique Delcenserie, Huiying Li, Jiaqi Wang. (2022) 2′-Fucosyllactose Ameliorates Inflammatory Bowel Disease by Modulating Gut Microbiota and Promoting MUC2 Expression. Frontiers in Nutrition, 9 (822020). [PMID:35252301] [10.3389/fnut.2022.822020] |
9. Xiuxiu Yang, Zhongqiang Yang. (2022) Simple and Rapid Detection of Ibuprofen─A Typical Pharmaceuticals and Personal Care Products─by a Liquid Crystal Aptasensor. LANGMUIR, 38 (1): (282–288). [PMID:34955019] [10.1021/acs.langmuir.1c02480] |
10. Liu Yaqing, Lin Xiaodong, Ji Xiangyi, Hao Zhe, Tao Zhanhui. (2020) Smartphone-based enzyme-free fluorescence sensing of organophosphate DDVP. MICROCHIMICA ACTA, 187 (7): (1-8). [PMID:32613298] [10.1007/s00604-020-04384-7] |
11. Xu Chen, Yanan Liu, Ange Lin, Na Huang, Liquan Long, Ye Gang, Jie Liu. (2018) Folic acid-modified mesoporous silica nanoparticles with pH-responsiveness loaded with Amp for an enhanced effect against anti-drug-resistant bacteria by overcoming efflux pump systems. Biomaterials Science, 6 (7): (1923-1935). [PMID:29850668] [10.1039/C8BM00262B] |
12. Wang Jun, Ma Kui, Yin Huanshun, Zhou Yunlei, Ai Shiyun. (2018) Aptamer based voltammetric determination of ampicillin using a single-stranded DNA binding protein and DNA functionalized gold nanoparticles. MICROCHIMICA ACTA, 185 (1): (1-7). [PMID:29594557] [10.1007/s00604-017-2566-8] |
13. Shi Hong, Liu Xueqing, Zhang Yuanfang. (2014) Fabrication of novel antimicrobial poly(vinyl chloride) plastic for automobile interior applications. IRANIAN POLYMER JOURNAL, 23 (4): (297-305). [PMID:] [10.1007/s13726-014-0226-y] |
14. Zhiwei Qie,Jialei Bai,Bin Xie,Lin Yuan,Nan Song,Yuan Peng,Xianjun Fan,Huanying Zhou,Fengchun Chen,Shuang Li,Baoan Ning,Zhixian Gao. (2015-06-11) Sensitive detection of atrazine in tap water using TELISA.. The Analyst, 140 ((15)): (5220-5226). [PMID:26061585] |
15. Jingyi Hu,Hai Huang,Yuan Che,Chujie Ding,Lu Zhang,Yun Wang,Haiping Hao,Hong Shen,Lijuan Cao. (2020-09-18) Qingchang Huashi Formula attenuates DSS-induced colitis in mice by restoring gut microbiota-metabolism homeostasis and goblet cell function.. Journal of ethnopharmacology, 266 (113394-113394). [PMID:32941971] |