Amredobresib , CAS No.A607622, Inhibitor of bromodomain containing 4

Item Number
A607622
Grouped product items
SKUSizeAvailabilityPrice Qty
A607622-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$126.90
A607622-5mg
5mg
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Production requires sourcing of materials. We appreciate your patience and understanding.
$332.90
A607622-10mg
10mg
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Production requires sourcing of materials. We appreciate your patience and understanding.
$569.90
A607622-25mg
25mg
Available within 8-12 weeks(?)
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$1,189.90

Basic Description

Synonyms1,2,4-Triazolo(4,3-a)pyrazin-8-amine, N,3-dimethyl-6-(6-(4-methyl-1-piperazinyl)-1-(phenylmethyl)-1hbenzimidazol-2-yl) | 6-(1-Benzyl-6-(4-methylpiperazin-1-yl)-1H-1,3-benzodiazol-2-yl)-N,3-dimethyl-(1,2,4)triazolo(4,3-a)pyrazin-8-amine | BI894999
Specifications & PurityMoligand™, ≥98%
Storage TempProtected from light,Store at -20°C
Shipped InIce chest + Ice pads
GradeMoligand™
Action TypeINHIBITOR
Mechanism of actionInhibitor of bromodomain containing 4
Product Description

Amredobresib is a potent inhibitor of BET. Amredobresib inhibits the binding of bromodomains to acetylated lysines on histone H3 and H4 and thus acts as important regulators of gene transcription. Amredobresib is useful for the research of acute myeloid leukemia (AML) and cancer (extracted from patent WO2019145410A1 and WO2021175824A1)。

Associated Targets(Human)

HIST1H4A Tchem Histone H4 (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
BRD4 Tchem Bromodomain-containing protein 4 (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Names and Identifiers

Molecular Weight 467.57

Certificates

Certificate of Analysis(COA)

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Chemical and Physical Properties

SensitivityLight & Moisture sensitive

Related Documents

Solution Calculators