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Amsacrine - ≥99%, high purity , DNA topoisomerase II inhibitor, CAS No.51264-14-3, DNA topoisomerase II inhibitor

Specifications & Purity:  ≥99%
Item Number
A303844
Grouped product items
SKUSizeAvailabilityPrice Qty
A303844-5mg
5mg
In stock
$35.90
A303844-10mg
10mg
In stock
$58.90
A303844-25mg
25mg
In stock
$83.90
A303844-50mg
50mg
In stock
$107.90
A303844-100mg
100mg
In stock
$137.90
A303844-250mg
250mg
In stock
$310.90

Discover Amsacrine by Aladdin Scientific in ≥99% for only $35.90. Available - in Ligands at Aladdin Scientific. DNA topoisomerase II inhibitor Tags: .

Basic Description

Synonymsamsacrine|51264-14-3|m-AMSA|Amsidine|Amsidyl|Acridinylanisidide|Lamasine|Amekrin|Amsacrina|mAMSA|AMSA|Acridinyl Anisidide|Amsacrinum|Amsine|4'-(9-Acridinylamino)methanesulfon-m-anisidide|amsidil|4'-(9-Acridinylamino)-3'-methoxymethanesulfonanilide|SN-1184
Specifications & Purity≥99%
Storage TempStore at -20°C
Shipped InDry ice
Action TypeINHIBITOR
Mechanism of actionDNA topoisomerase II inhibitor

Product Properties

ALogP4

Associated Targets

KCNH2 Tclin Potassium voltage-gated channel subfamily H member 2 2 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Names and Identifiers

IUPAC Name N-[4-(acridin-9-ylamino)-3-methoxyphenyl]methanesulfonamide
INCHI InChI=1S/C21H19N3O3S/c1-27-20-13-14(24-28(2,25)26)11-12-19(20)23-21-15-7-3-5-9-17(15)22-18-10-6-4-8-16(18)21/h3-13,24H,1-2H3,(H,22,23)
InChi Key XCPGHVQEEXUHNC-UHFFFAOYSA-N
Canonical SMILES COC1=C(C=CC(=C1)NS(=O)(=O)C)NC2=C3C=CC=CC3=NC4=CC=CC=C42
Isomeric SMILES COC1=C(C=CC(=C1)NS(=O)(=O)C)NC2=C3C=CC=CC3=NC4=CC=CC=C42
PubChem CID 2179
Molecular Weight 393.46

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6 results found

Lot NumberCertificate TypeDateItem
L2216288Certificate of AnalysisSep 19, 2022 A303844
L2216289Certificate of AnalysisSep 19, 2022 A303844
L2216290Certificate of AnalysisSep 19, 2022 A303844
L2216291Certificate of AnalysisSep 19, 2022 A303844
L2216295Certificate of AnalysisSep 19, 2022 A303844
L2216296Certificate of AnalysisSep 19, 2022 A303844

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References

1. Pasquina L et al..  (2016)  A synthetic lethal approach for compound and target identification in Staphylococcus aureus..  Nat Chem Biol,  12  (40-5).  [PMID:26619249]
2. Matano LM et al..  (2016)  Accelerating the discovery of antibacterial compounds using pathway-directed whole cell screening..  Bioorg Med Chem,  24  (24): (6307-6314).  [PMID:27594549]
3. Schaefer K et al..  (2017)  In vitro reconstitution demonstrates the cell wall ligase activity of LCP proteins..  Nat Chem Biol,  13  (4): (396-401).  [PMID:28166208]

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