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Amygdalin - analytical standard,>98%, high purity , CAS No.29883-15-6

  • analytical standard
  • ≥98%
Item Number
A107073
Grouped product items
SKUSizeAvailabilityPrice Qty
A107073-20mg
20mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$9.90
A107073-500mg
500mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$30.90
A107073-1g
1g
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$47.90
A107073-5g
5g
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$71.90

Glycosidic antineoplastic agent

Basic Description

Synonyms(R)-Amygdalin | AMYGDALIN [MI] | 214UUQ9N0H | XUCIJNAGGSZNQT-JHSLDZJXSA-N | Vitamin B17 | amygdalin | HSDB 3559 | bmse000139 | (2R)-((6-O-beta-D-glucopyranosyl-beta-D-glucopyranosyl)oxy)(phenyl)acetonitrile | (R)-alpha-((6-O-beta-D-glucopyranosyl-beta-D-
Specifications & Purityanalytical standard, ≥98%
Biochemical and Physiological MechanismsGlycosidic antineoplastic agent. Induces apoptosis through the BCL pathway. Inhibits angiogenesis and displays antitumor effects in vivo. Orally active.
Shipped InNormal
Gradeanalytical standard
NoteWherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description

Amygdalin (Laetrile) has antifibrotic, antitumor, anti-inflammatory and analgesic effects, amygdalin joint HSYA could inhibit the degeneration of the endplate chondrocytes derived from intervertebral discs of rats induced by IL-1beta and better than the single use of Amygdalin or HSYA. Amygdalin induces apoptotic cell death in human DU145 and LNCaP prostate cancer cells by caspase-3 activation through down-regulation of Bcl-2 and up-regulation of Bax.

Names and Identifiers

IUPAC Name (2R)-2-phenyl-2-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-[[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]oxan-2-yl]oxyacetonitrile
INCHI InChI=1S/C20H27NO11/c21-6-10(9-4-2-1-3-5-9)30-20-18(28)16(26)14(24)12(32-20)8-29-19-17(27)15(25)13(23)11(7-22)31-19/h1-5,10-20,22-28H,7-8H2/t10-,11+,12+,13+,14+,15-,16-,17+,18+,19+,20+/m0/s1
InChi Key XUCIJNAGGSZNQT-JHSLDZJXSA-N
Canonical SMILES OC[C@H]1O[C@@H](OC[C@H]2O[C@@H](OC(C#N)c3ccccc3)[C@H](O)[C@@H](O)[C@@H]2O)[C@H](O)[C@@H](O)[C@@H]1O
Isomeric SMILES C1=CC=C(C=C1)[C@H](C#N)O[C@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CO[C@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CO)O)O)O)O)O)O
WGK Germany 3
RTECS OO8450000
PubChem CID 656516
Molecular Weight 457.43
Beilstein 66856
Reaxy-Rn 1695110

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section

4 results found

Lot NumberCertificate TypeDateItem
H2205749Certificate of AnalysisMay 20, 2024 A107073
H2205750Certificate of AnalysisMay 20, 2024 A107073
H2205751Certificate of AnalysisMay 20, 2024 A107073
A1915147Certificate of AnalysisAug 11, 2022 A107073

Chemical and Physical Properties

SolubilitySolubility:H2O;DMSO
Specific Rotation[α]-40 ° (C=2, H2O)
Melt Point(°C)223-226°C

Safety and Hazards(GHS)

Pictogram(s) GHS07
Signal Warning
Hazard Statements

H302:Harmful if swallowed

Precautionary Statements

P501:Dispose of contents/container to ...

P264:Wash hands [and …] thoroughly after handling.

P270:Do not eat, drink or smoke when using this product.

P330:Rinse mouth.

P301+P317:IF SWALLOWED: Get medical help.

WGK Germany 3
RTECS OO8450000
Reaxy-Rn 1695110

Related Documents

Solution Calculators