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AN-9 - ≥95%, high purity , CAS No.122110-53-6
an HDAC inhibitor with antimetastic and antiangiogenic properties
Basic Description Synonyms AN-9;Pivalyloxymethyl butyrate | butanoyloxymethyl 2,2-dimethylpropanoate | Pivalyloxymethyl butyrate | Butanoic acid, (2,2-dimethyl-1-oxopropoxy)methyl ester | AN-9 | BRN 4861411 | CS-0078203 | Pivanex | UNII-55VNK5440P | pivaloyloxymethylbutyrate | AN 9 Specifications & Purity ≥95% Biochemical and Physiological Mechanisms Pivanex (AN-9), a derivative of Butyric acid, is an orally active HDAC inhibitor. Pivanex down-regulates bcr-abl protein and enhances apoptosis. Pivanex has antimetastic and antiangiogenic properties. Storage Temp Store at -20°C Shipped In Ice chest + Ice pads Product Description AN-9 is an HDAC inhibitor with antimetastic and antiangiogenic properties. AN-9 is theorized to reduce vascularization and the expression of bFGF and HIF-1
Associated Targets(Human) Associated Targets(non-human) Names and Identifiers Pubchem Sid 488183405 Pubchem Sid Url https://pubchem.ncbi.nlm.nih.gov/substance/488183405 IUPAC Name butanoyloxymethyl 2,2-dimethylpropanoate INCHI InChI=1S/C10H18O4/c1-5-6-8(11)13-7-14-9(12)10(2,3)4/h5-7H2,1-4H3 InChi Key GYKLFBYWXZYSOW-UHFFFAOYSA-N Canonical SMILES CCCC(=O)OCOC(=O)C(C)(C)C Isomeric SMILES CCCC(=O)OCOC(=O)C(C)(C)C PubChem CID 60748 Molecular Weight 202.25 Beilstein 4861411
Chemical and Physical Properties Solubility Soluble in DMSO (≥10 mg/ml). Refractive Index n20D1.43 (Predicted) Boil Point(°C) 88-93° C at 2 mmHg Melt Point(°C) -53.20° C (Predicted)
Safety and Hazards(GHS) RIDADR NONHforallmodesoftransport
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