Anabaseine , CAS No.3471-05-4

Item Number
A276289
Grouped product items
SKUSizeAvailabilityPrice Qty
A276289-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$99.90
A276289-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$169.90

Neurotoxin. Potent, competitive α7 nACh receptor agonist.

Basic Description

Synonyms2,3'-BIPYRIDINE, 3,4,5,6-TETRAHYDRO- | FT-0662139 | HY-115766 | Q19903288 | J-019727 | CS-0255607 | BDBM109773 | US8609708, 74 Anabaseine | AN4 | AKOS000277414 | 3-(3,4,5,6-tetrahydropyridin-2-yl)pyridine | DYE103K23I | UNII-DYE103K23I | 3-(2,3,4,5-tetrah
Biochemical and Physiological MechanismsNeurotoxin. Potent, competitive α7 nACh receptor agonist. Weak, partial α4β2 agonist. GTS-21 dihydrochloride precursor. ( R,S )-Anabasine analog. Shows neurotoxic effects in vivo.
Storage TempStore at 2-8°C
Shipped InWet ice
NoteWherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Toxic, refer to SDS for further information . Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description

Store at +4°C. The product can be stored for up to 12 months.

Associated Targets(Human)

CHRNA7 Tchem Neuronal acetylcholine receptor protein alpha-7 subunit (3524 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CYP3A4 Tclin Cytochrome P450 3A4 (53859 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CYP2A6 Tchem Cytochrome P450 2A6 (2861 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CHRNB2 Tclin Neuronal acetylcholine receptor; alpha4/beta2 (3972 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

Pseudomonas aeruginosa (123386 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Acinetobacter baumannii (41033 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Chrna3 Neuronal acetylcholine receptor; alpha3/beta4 (1368 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

IUPAC Name 3-(2,3,4,5-tetrahydropyridin-6-yl)pyridine
INCHI InChI=1S/C10H12N2/c1-2-7-12-10(5-1)9-4-3-6-11-8-9/h3-4,6,8H,1-2,5,7H2
InChi Key AUBPMADJYNSPOA-UHFFFAOYSA-N
Canonical SMILES C1CCN=C(C1)C2=CN=CC=C2
Isomeric SMILES C1CCN=C(C1)C2=CN=CC=C2
PubChem CID 18985
Molecular Weight 160.22

Certificates

Certificate of Analysis(COA)

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Related Documents

Solution Calculators