angiotensin IV, CAS No.rp173476, Agonist of AT 1 receptor

Features and benefits
    Item Number
    rp173476
    Grouped product items
    SKUSizeAvailabilityPrice Qty
    rp173476-500μg
    500μg
    Available within 8-12 weeks(?)
    Production requires sourcing of materials. We appreciate your patience and understanding.
    $1,334.90
    rp173476-1mg
    1mg
    Available within 8-12 weeks(?)
    Production requires sourcing of materials. We appreciate your patience and understanding.
    $2,334.90
    View related series
    AT1 receptor Agonist

    Basic Description

    Product Nameangiotensin IV, CAS No.rp173476
    SynonymsAlanine, 3-phenyl-N-(1-(N-(N-(N-valyltyrosyl)isoleucyl)histidyl)prolyl)- | CAS_12676-15-2 | Angiotensin IV | Human angiotensin hexapeptide (3-8) | Angiotensin II, des-aspartyl(1)-des-arginyl(2)-isoleucine(5)- | DTXSID701347717 | Huamn angiotensin (3-8) |
    GradeMoligand™
    Specifications & PurityMoligand™
    Action TypeAGONIST
    Mechanism of actionAgonist of AT 1 receptor

    Associated Targets(Human)

    AGTR1 Tclin Type-1 angiotensin II receptor (0 Activities)
    Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
    AGTR1 Tclin Type-1 angiotensin II receptor (5176 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    ANPEP Tchem Aminopeptidase N (863 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    LNPEP Tchem Cystinyl aminopeptidase (313 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    ERAP2 Tchem Endoplasmic reticulum aminopeptidase 2 (387 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    KDM4A Tchem Lysine-specific demethylase 4A (52245 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    ERAP1 Tchem Endoplasmic reticulum aminopeptidase 1 (581 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    CBX1 Tbio Chromobox protein homolog 1 (92434 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    GLS Tchem Glutaminase kidney isoform, mitochondrial (16997 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

    Associated Targets(non-human)

    ampC Beta-lactamase AmpC (62480 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Cruzipain (33337 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    AGTR1 Angiotensin II type 1a (AT-1a) receptor (440 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    LAP M17 leucyl aminopeptidase (931 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

    Mechanisms of Action

    Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

    Product Specifications

    CASrp173476

    Certificates

    Certificate of Analysis(COA)

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    Genetic information

    Alternate NamesAlanine, 3-phenyl-N-(1-(N-(N-(N-valyltyrosyl)isoleucyl)histidyl)prolyl)- | CAS_12676-15-2 | Angiotensin IV | Human angiotensin hexapeptide (3-8) | Angiotensin II, des-aspartyl(1)-des-arginyl(2)-isoleucine(5)- | DTXSID701347717 | Huamn angiotensin (3-8) |
    Reference
    • 1. Kinetics and inhibition of recombinant human cystathionine gamma-lyase. Toward the rational control of transsulfuration., The Journal of biological chemistry, Steegborn, C C and 7 more authors.
    • 2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences., Proceedings of the National Academy of Sciences of the United States of America, Strausberg, Robert L RL and 83 more authors.
    • 3. Genomic basis of cystathioninuria (MIM 219500) revealed by multiple mutations in cystathionine gamma-lyase (CTH)., Human genetics, Wang, Jian J and Hegele, Robert A RA.
    • 4. Cloning and nucleotide sequence of human liver cDNA encoding for cystathionine gamma-lyase., Biochemical and biophysical research communications, Lu, Y Y, O'Dowd, B F BF, Orrego, H H and Israel, Y Y.
    • 5. Single nucleotide polymorphism in CTH associated with variation in plasma homocysteine concentration., Clinical genetics, Wang, J J, Huff, A M AM, Spence, J D JD and Hegele, R A RA.
    • 6. Cystathionine gamma-lyase overexpression inhibits cell proliferation via a H2S-dependent modulation of ERK1/2 phosphorylation and p21Cip/WAK-1., The Journal of biological chemistry, Yang, Guangdong G, Cao, Kun K, Wu, Lingyun L and Wang, Rui R.
    • 7. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)., Genome research, Gerhard, Daniela S DS and 115 more authors.
    • 8. Towards a proteome-scale map of the human protein-protein interaction network., Nature, Rual, Jean-François JF and 37 more authors.
    • 9. The DNA sequence and biological annotation of human chromosome 1., Nature, Gregory, S G SG and 178 more authors.
    • 10. Polymorphisms in one-carbon metabolism and trans-sulfuration pathway genes and susceptibility to bladder cancer., International journal of cancer, Moore, Lee E LE and 14 more authors. more

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