Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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A110660-100g | 100g | In stock | $41.90 | |
A110660-500g | 500g | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $146.90 |
NSAID. Non-selective COX inhibitor.
Synonyms | PHENAZONE [EP IMPURITY] | Prestwick1_000029 | BPBio1_000107 | PHENAZONE [MART.] | Prestwick2_000029 | Spectrum_000058 | UNII-T3CHA1B51H | Azophen | Antipirin | NCGC00016274-04 | SCHEMBL20452 | Sedatin | 1,2-Dihydro-1,5-dimethyl-2-phenyl-3H-pyrazol-3-one | |
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Specifications & Purity | ≥99% |
Biochemical and Physiological Mechanisms | Antipyrine also referred to as phenazone or phenazonum is an anti-inflammatory agent that possesses analgesic, antipyretic and platelet-inhibitory actions.NSAID. Non-selective COX inhibitor. Inhibits prostaglandin synthesis. Centrally active. Shows anti-i |
Storage Temp | Protected from light,Store at -20°C |
Shipped In | Ice chest + Ice pads |
Note | Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details. |
Product Description | Antipyrine is an analgesic intended for research use. |
ALogP | 0.4 |
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IUPAC Name | 1,5-dimethyl-2-phenylpyrazol-3-one |
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INCHI | InChI=1S/C11H12N2O/c1-9-8-11(14)13(12(9)2)10-6-4-3-5-7-10/h3-8H,1-2H3 |
InChi Key | VEQOALNAAJBPNY-UHFFFAOYSA-N |
Canonical SMILES | CC1=CC(=O)N(N1C)C2=CC=CC=C2 |
Isomeric SMILES | CC1=CC(=O)N(N1C)C2=CC=CC=C2 |
WGK Germany | 1 |
RTECS | CD2450000 |
PubChem CID | 2206 |
Molecular Weight | 188.23 |
Beilstein | 157775 |
Reaxy-Rn | 157775 |
Enter Lot Number to search for COA:
Find and download the COA for your product by matching the lot number on the packaging.
Lot Number | Certificate Type | Date | Item |
---|---|---|---|
K2427345 | Certificate of Analysis | Dec 03, 2024 | A110660 |
K2427346 | Certificate of Analysis | Nov 20, 2024 | A110660 |
G2431060 | Certificate of Analysis | Jul 10, 2024 | A110660 |
G2431059 | Certificate of Analysis | Jul 10, 2024 | A110660 |
G2431058 | Certificate of Analysis | Jul 10, 2024 | A110660 |
G2431057 | Certificate of Analysis | Jul 10, 2024 | A110660 |
G2431056 | Certificate of Analysis | Jul 10, 2024 | A110660 |
G2431055 | Certificate of Analysis | Jul 10, 2024 | A110660 |
L2325153 | Certificate of Analysis | Dec 15, 2023 | A110660 |
L2325152 | Certificate of Analysis | Dec 15, 2023 | A110660 |
L2325151 | Certificate of Analysis | Dec 15, 2023 | A110660 |
G2321394 | Certificate of Analysis | Jul 01, 2023 | A110660 |
G2321386 | Certificate of Analysis | Jul 01, 2023 | A110660 |
G2321376 | Certificate of Analysis | Jul 01, 2023 | A110660 |
G2321373 | Certificate of Analysis | Jul 01, 2023 | A110660 |
G2321327 | Certificate of Analysis | Jul 01, 2023 | A110660 |
B2318661 | Certificate of Analysis | Feb 08, 2023 | A110660 |
B2318657 | Certificate of Analysis | Feb 08, 2023 | A110660 |
B2318651 | Certificate of Analysis | Feb 08, 2023 | A110660 |
B2207281 | Certificate of Analysis | Jan 04, 2022 | A110660 |
B2207173 | Certificate of Analysis | Jan 04, 2022 | A110660 |
B2207119 | Certificate of Analysis | Jan 04, 2022 | A110660 |
Solubility | Soluble in water, ethanol, chloroform (1000 mg/ml), ether (23.26 mg/ml), and DMSO (38 mg/ml at 25° C). |
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Sensitivity | Light sensitive. |
Refractive Index | 1.5697 |
Boil Point(°C) | 319°C |
Melt Point(°C) | 114°C |
Pictogram(s) | GHS08, GHS07 |
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Signal | Danger |
Hazard Statements | H315:Causes skin irritation H319:Causes serious eye irritation H302:Harmful if swallowed H370:Causes damage to organs |
Precautionary Statements | P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P260:Do not breathe dust/fume/gas/mist/vapors/spray. P270:Do not eat, drink or smoke when using this product. P337+P313:IF eye irritation persists: Get medical advice/attention. P362+P364:Take off contaminated clothing and wash it before reuse. P332+P313:IF SKIN irritation occurs: Get medical advice/attention. P308+P311:IF exposed or concerned: Call a POISON CENTER/doctor/... P301+P312+P330:IF SWALLOWED: Call a POISON CENTER/ doctor if you feel unwell. Rinse mouth. |
WGK Germany | 1 |
RTECS | CD2450000 |
Reaxy-Rn | 157775 |
Merck Index | 716 |
Starting at $43.90
Starting at $42.90
1. Shilong Jiang, Song Cheng, Jiashun Cao, Cailiang Yue, Jianglei Xiong, Cong Jiang, Hongzhan Cai, Jianhua Wu. (2024) Monodispersed Co-N3 loaded carbon nitride mediated peroxymonosulfate activation for rapid degradation of trace urea via singlet oxygen. CHEMICAL ENGINEERING JOURNAL, 479 (10): (147526). [PMID:21659603] [10.1016/j.cej.2023.147526] |
2. Yuqiong Gao, Han Ning, Yanyan Rao, Kexuan Li, Chaole Zeng, Naiyun Gao. (2023) Efficient elimination of phenazone by an electro-assisted Fe3+-EDDS/PS process at neutral pH: Kinetics, mechanistic insights and toxicity evaluation. CHEMOSPHERE, 328 (138598). [PMID:37028723] [10.1016/j.chemosphere.2023.138598] |
3. Wanbao Wu, Yihong Liang, Deping Li, Yiyang Bo, Dong Wu, Lijie Ci, Mingyu Li, Jiaheng Zhang. (2022) A Competitive Solvation of Ternary Eutectic Electrolytes Tailoring the Electrode/Electrolyte Interphase for Lithium Metal Batteries. ACS Nano, 16 (9): (14558–14568). [PMID:36040142] [10.1021/acsnano.2c05016] |
1. Shilong Jiang, Song Cheng, Jiashun Cao, Cailiang Yue, Jianglei Xiong, Cong Jiang, Hongzhan Cai, Jianhua Wu. (2024) Monodispersed Co-N3 loaded carbon nitride mediated peroxymonosulfate activation for rapid degradation of trace urea via singlet oxygen. CHEMICAL ENGINEERING JOURNAL, 479 (10): (147526). [PMID:21659603] [10.1016/j.cej.2023.147526] |
2. Yuqiong Gao, Han Ning, Yanyan Rao, Kexuan Li, Chaole Zeng, Naiyun Gao. (2023) Efficient elimination of phenazone by an electro-assisted Fe3+-EDDS/PS process at neutral pH: Kinetics, mechanistic insights and toxicity evaluation. CHEMOSPHERE, 328 (138598). [PMID:37028723] [10.1016/j.chemosphere.2023.138598] |
3. Wanbao Wu, Yihong Liang, Deping Li, Yiyang Bo, Dong Wu, Lijie Ci, Mingyu Li, Jiaheng Zhang. (2022) A Competitive Solvation of Ternary Eutectic Electrolytes Tailoring the Electrode/Electrolyte Interphase for Lithium Metal Batteries. ACS Nano, 16 (9): (14558–14568). [PMID:36040142] [10.1021/acsnano.2c05016] |