Basic Description

Synonyms	diadenosine triphosphate \| Ap3A \| 5959-90-0 \| 5'Ap3A \| Adenosine(3)triphosphate adenosine \| BIS(ADENOSINE)-5'-TRIPHOSPHATE \| ApppA \| CHEMBL407938 \| CHEBI:27775 \| Adenosine 5'-triphosphate 5'-adenosine \| A(5')p3(5')A \| adenosine(5')triphospho(5')adenosine \| P1,P3-Bis(5'-adenosyl)
Specifications & Purity	Moligand™
Grade	Moligand™
Action Type	AGONIST
Mechanism of action	Agonist of P2Y 1 receptor

Associated Targets(Human)

P2RY1 Tchem P2Y purinoceptor 1 (0 Activities)

Discover Target: P2RY1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

P2RY1 Tchem Purinergic receptor P2Y1 (1327 Activities)

Discover Target: P2RY1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

P2RY2 Tclin Purinergic receptor P2Y2 (1109 Activities)

Discover Target: P2RY2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

FHIT Tchem Bis(5'-adenosyl)-triphosphatase (95 Activities)

Discover Target: FHIT

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

NUDT3 Tbio Diphosphoinositol polyphosphate phosphohydrolase 1 (15 Activities)

Discover Target: NUDT3

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

NUDT10 Tbio Diphosphoinositol polyphosphate phosphohydrolase 3-alpha (12 Activities)

Discover Target: NUDT10

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

NUDT4 Tbio Diphosphoinositol polyphosphate phosphohydrolase 2 (12 Activities)

Discover Target: NUDT4

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Associated Targets(non-human)

Eif4e Eukaryotic translation initiation factor 4E (654 Activities)

Discover Target: Eif4e

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mechanisms of Action

Mechanism of Action	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	References

Names and Identifiers

IUPAC Name	{[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}({[({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)phosphinic acid
INCHI	InChI=1S/C20H27N10O16P3/c21-15-9-17(25-3-23-15)29(5-27-9)19-13(33)11(31)7(43-19)1-41-47(35,36)45-49(39,40)46-48(37,38)42-2-8-12(32)14(34)20(44-8)30-6-28-10-16(22)24-4-26-18(10)30/h3-8,11-14,19-20,31-34H,1-2H2,(H,35,36)(H,37,38)(H,39,40)(H2,21,23,25)(H2,22,24,26)/t7-,8-,11-,12-,13-,14-,19-,20-/m1/s1
InChi Key	QCICUPZZLIQAPA-XPWFQUROSA-N
Canonical SMILES	O[C@@H]1[C@@H](COP(=O)(OP(=O)(OP(=O)(OC[C@H]2O[C@H]([C@@H]([C@@H]2O)O)n2cnc3c2ncnc3N)O)O)O)O[C@H]([C@@H]1O)n1cnc2c1ncnc2N
Isomeric SMILES	C1=NC(=C2C(=N1)N(C=N2)[C@H]3[C@@H]([C@@H]([C@H](O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)OC[C@@H]4[C@H]([C@H]([C@@H](O4)N5C=NC6=C(N=CN=C65)N)O)O)O)O)N
PubChem CID	165381

Database links

PubChem CID	165381
ChEMBL Ligand	CHEMBL407938
RCSB PDB Ligand	BA3
GPCRdb Ligand	Ap3a

Certificates

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SKU	Size	Availability	Price	Qty
A607670-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$1,334.90
A607670-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$2,000.90

Ap3a , CAS No.A607670, Agonist of P2Y 1 receptor