APC 366, CAS No.158921-85-8

  • ≥98%
Features and benefits
    Item Number
    A287530
    Grouped product items
    SKUSizeAvailabilityPrice Qty
    A287530-5mg
    5mg
    Available within 8-12 weeks(?)
    Production requires sourcing of materials. We appreciate your patience and understanding.
    $242.90

    Tryptase inhibitor

    Basic Description

    Product NameAPC 366, CAS No.158921-85-8
    SynonymsAPC 366 | 158921-85-8 | N-(1-Hydroxy-2-naphthoyl)-L-arginyl-L-prolinamide | 1-Hydroxy-2-naphthoyl-Arg-Pro amide | BOSAPTLE0I | 178925-65-0 | (2S)-1-[(2S)-5-(diaminomethylideneamino)-2-[(1-hydroxynaphthalene-2-carbonyl)amino]pentanoyl]pyrrolidine-2-carboxamide | L-Proli
    Specifications & Purity≥98%
    Biochemical and Physiological MechanismsSelective inhibitor of mast cell tryptase (Ki= 7.1μM) that inhibits tryptase-induced histamine release from human tonsil and lung cells. Reduces airway inflammation and blocks postchallenge airway hyperresponsivenessin vivo.
    SequenceN-(1-Hydroxy-2-naphthoyl)-L-arginyl-L-prolinamide

    Associated Targets(Human)

    TPSD1 Tbio Tryptase delta 0 Activities

    Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

    Associated Targets(non-human)

    Tryptase 1 Activities

    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

    SARS-CoV-2 38078 Activities

    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

    Product Specifications

    Storage TempStore at -20°C
    Shipped InIce chest + Ice pads
    CAS158921-85-8

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