Apigenin - analytical standard,≥98%, high purity , CAS No.520-36-5, Activator of CFTR

36 Citations
Item Number
A106675
Grouped product items
SKUSizeAvailabilityPrice Qty
A106675-20mg
20mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$58.90
A106675-100mg
100mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$218.90
A106675-500mg
500mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$874.90

Anticancer agent

View related series
CFTR Activator

Basic Description

SynonymsChamomile | Apigenine | Versulin | 5,7-Dihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one | 5,7-dihydroxy-2-(4-hydroxyphenyl)chromen-4-one | C.I. Natural Yellow 1 | 5,7,4'-Trihydroxyflavone | Apigenol | 4',5,7-Trihydroxyflavone | Pelargidenon 1449 | Spigenin
Specifications & PurityMoligand™, analytical standard, ≥98%
Biochemical and Physiological MechanismsPlant flavone. Antioxidant, anti-inflammatory and anticancer properties. Effects a wide range of molecular targets including caspases, fatty acid synthase, topoisomerase and nuclear factor-κB.
Storage TempStore at 2-8°C,Protected from light,Argon charged
Shipped InWet ice
Gradeanalytical standard, Moligand™
Action TypeACTIVATOR
Mechanism of actionActivator of CFTR
NoteWherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Associated Targets(Human)

CYP1A2 Tchem Cytochrome P450 1A2 (3 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
CYP1B1 Tchem Cytochrome P450 1B1 (3 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
CFTR Tclin Cystic fibrosis transmembrane conductance regulator (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
DPP4 Tclin Dipeptidyl peptidase 4 (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
HSD17B1 Tchem Estradiol 17-beta-dehydrogenase 1 (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
PSMB5 Tclin Proteasome subunit beta type-5 (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
TTR Tclin Transthyretin (2 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
CYP19A1 Tclin Aromatase (2 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
CYP1A1 Tchem Cytochrome P450 1A1 (2 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
XDH Tclin Xanthine dehydrogenase/oxidase (2 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
ACHE Tclin Acetylcholinesterase (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
MAOA Tclin Amine oxidase [flavin-containing] A (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
PDE5A Tclin Phosphodiesterase 5A (5113 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
EGFR Tclin Epidermal growth factor receptor erbB1 (33727 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ESR1 Tclin Estrogen receptor alpha (17718 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
NR3C1 Tclin Glucocorticoid receptor (14987 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
INSR Tclin Insulin receptor (5558 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PRSS1 Tclin Trypsin I (2306 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ALOX5 Tclin Arachidonate 5-lipoxygenase (6568 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
AR Tclin Androgen Receptor (11781 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
TOP2A Tclin DNA topoisomerase II alpha (6317 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
VDR Tclin Vitamin D receptor (26531 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CYP19A1 Tclin Cytochrome P450 19A1 (6099 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ACE Tclin Angiotensin-converting enzyme (1423 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
TYR Tclin Tyrosinase (717 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
TSHR Tclin Thyroid stimulating hormone receptor (29986 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MAOA Tclin Monoamine oxidase A (11911 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ACHE Tclin Acetylcholinesterase (18204 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PTGS1 Tclin Cyclooxygenase-1 (9233 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MAOB Tclin Monoamine oxidase B (8835 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ADORA1 Tclin Adenosine A1 receptor (17603 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PTGS2 Tclin Cyclooxygenase-2 (13999 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
OPRM1 Tclin Mu opioid receptor (19785 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PPARG Tclin Peroxisome proliferator-activated receptor gamma (15191 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
OPRD1 Tclin Delta opioid receptor (15096 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
OPRK1 Tclin Kappa opioid receptor (16155 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
XDH Tclin Xanthine dehydrogenase (1038 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PTH1R Tclin Parathyroid hormone receptor (47172 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PPARA Tclin Peroxisome proliferator-activated receptor alpha (9197 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ESR2 Tclin Estrogen receptor beta (9272 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ELANE Tclin Leukocyte elastase (8173 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
AKR1B1 Tclin Aldose reductase (1404 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ADORA2A Tclin Adenosine A2a receptor (16305 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
THRB Tclin Thyroid hormone receptor beta-1 (7926 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
RXRA Tclin Retinoid X receptor alpha (3637 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ADORA3 Tchem Adenosine A3 receptor (15931 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CXCL8 Tchem Interleukin-8 (642 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CSNK2A1 Tchem Casein kinase II alpha (3512 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
DAPK3 Tchem Death-associated protein kinase 3 (2108 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MAPK11 Tchem MAP kinase p38 beta (2785 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
LCK Tclin Tyrosine-protein kinase LCK (9212 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CYP1B1 Tchem Cytochrome P450 1B1 (1148 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PON1 Tbio Serum paraoxonase/arylesterase 1 (96 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MAPK14 Tchem MAP kinase p38 alpha (12866 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GSK3B Tclin Glycogen synthase kinase-3 beta (11785 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MAP2K6 Tchem Dual specificity mitogen-activated protein kinase kinase 6 (1284 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CSNK1G1 Tchem Casein kinase I gamma 1 (2496 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CAMK2B Tchem CaM kinase II beta (1626 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CDK6 Tclin Cyclin-dependent kinase 6 (1724 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CHEK2 Tchem Serine/threonine-protein kinase Chk2 (4015 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
BCHE Tclin Butyrylcholinesterase (7174 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MPO Tchem Myeloperoxidase (1002 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

NA Neuraminidase (1107 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ddlB D-alanylalanine synthetase (66 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
pol Human immunodeficiency virus type 1 reverse transcriptase (18245 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
TPR Trypanothione reductase (189 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Ttr Transthyretin (14 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Cruzipain (33337 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Gusb Beta-glucuronidase (17 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
DPP4 Dipeptidyl peptidase IV (11 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Abcc1 Multidrug resistance-associated protein 1 (42 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Ppard Peroxisome proliferator-activated receptor delta (358 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Abcb1b P-glycoprotein 1 (174 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mapk1 MAP kinase ERK2 (650 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Hdac6 Histone deacetylase 6 (222 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Ptpn1 Protein-tyrosine phosphatase 1B (270 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Pkm Pyruvate kinase isozymes M1/M2 (66 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Lyz1 Lysozyme C (11 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
pol Human immunodeficiency virus type 1 integrase (9041 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Camk2g CaM kinase II gamma (1 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Pfmrk Protein kinase Pfmrk (149 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Helicobacter pylori (3113 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Pseudomonas aeruginosa (123386 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Klebsiella pneumoniae (43867 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Proteus vulgaris (5823 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Salmonella typhimurium (15756 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Staphylococcus aureus (210822 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Staphylococcus epidermidis (22802 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Escherichia coli (133304 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Proteus mirabilis (3894 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Aspergillus niger (16508 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Bacillus subtilis (32866 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mycobacterium tuberculosis (203094 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Phytophthora infestans (820 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Saccharomyces cerevisiae (19171 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Rhizomucor miehei (120 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Penicillium chrysogenum (1593 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Trypanosoma brucei brucei (13300 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Entamoeba histolytica (2676 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Plasmodium falciparum (966862 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Cryptococcus neoformans (21258 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Candida albicans (78123 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Candida parapsilosis (8521 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Trichophyton rubrum (3646 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Trichosporon beigelii (253 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Leishmania amazonensis (3813 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Leishmania donovani (89745 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Trypanosoma cruzi (99888 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mus musculus (284745 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Rattus norvegicus (775804 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Human alphaherpesvirus 1 (11089 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Human immunodeficiency virus 1 (70413 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Names and Identifiers

IUPAC Name 5,7-dihydroxy-2-(4-hydroxyphenyl)chromen-4-one
INCHI InChI=1S/C15H10O5/c16-9-3-1-8(2-4-9)13-7-12(19)15-11(18)5-10(17)6-14(15)20-13/h1-7,16-18H
InChi Key KZNIFHPLKGYRTM-UHFFFAOYSA-N
Canonical SMILES C1=CC(=CC=C1C2=CC(=O)C3=C(C=C(C=C3O2)O)O)O
Isomeric SMILES C1=CC(=CC=C1C2=CC(=O)C3=C(C=C(C=C3O2)O)O)O
WGK Germany 3
RTECS LK9276000
PubChem CID 5280443
Molecular Weight 270.24
Beilstein 262620
Reaxy-Rn 262620

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Find and download the COA for your product by matching the lot number on the packaging.

9 results found

Lot NumberCertificate TypeDateItem
B2423370Certificate of AnalysisJan 18, 2024 A106675
L2109455Certificate of AnalysisSep 21, 2023 A106675
C2329721Certificate of AnalysisFeb 16, 2023 A106675
C2329722Certificate of AnalysisFeb 16, 2023 A106675
C2329723Certificate of AnalysisFeb 16, 2023 A106675
C2329725Certificate of AnalysisFeb 16, 2023 A106675
C2329726Certificate of AnalysisFeb 16, 2023 A106675
C2329727Certificate of AnalysisFeb 16, 2023 A106675
B2318468Certificate of AnalysisNov 24, 2021 A106675

Chemical and Physical Properties

SensitivityLight sensitive.
Melt Point(°C)345-350°C

Safety and Hazards(GHS)

Pictogram(s) GHS07
Hazard Statements

H315:Causes skin irritation

H319:Causes serious eye irritation

H335:May cause respiratory irritation

Precautionary Statements

P261:Avoid breathing dust/fume/gas/mist/vapors/spray.

P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.

WGK Germany 3
RTECS LK9276000
Reaxy-Rn 262620
Merck Index 730

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Citations of This Product

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3. Shucheng Liu, Zhi Hu, Xuan Zhang, Hao Huang, Jianming Pan, Hongxiang Ou.  (2024)  Fabrication of double imprinted anchor points in cellulose nanocrystals-based hierarchical porous polyHIPEs for selective separation of flavoniods under physiological pH.  JOURNAL OF HAZARDOUS MATERIALS,  465  (133230).  [PMID:38134695]
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5. Dan Wang, He Li, Tian-Yu Hou, Zhi-Jun Zhang, Hui-Zhen Li.  (2023)  Effects of conjugated interactions between Perilla seed meal proteins and different polyphenols on the structural and functional properties of proteins.  FOOD CHEMISTRY,    (137345).  [PMID:37666124]
6. Mingcai Ma, Xiaofeng Lu, Licheng Wang, Yong Guo, Hui Ding, Shuai Wang, Xiaojing Liang.  (2023)  A stable core-shell metal-organic framework@covalent organic framework composite as solid-phase extraction adsorbent for selective enrichment and determination of flavonoids.  JOURNAL OF CHROMATOGRAPHY A,  1707  (464324).  [PMID:37634259]
7. Shuang Xiao, Peng Zhang, Guowen Zhang, Wenwen Li, Haowen Lin, Xing Hu.  (2023)  Inhibition of toll-like receptor 4 activation by apigenin and chrysin via competition for sites and conformational changes.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,  252  (126415).  [PMID:37598817]
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13. Jingtong Xia, Jiahao Zhou, Yanlong Liu, Na Yan, Xiaowen Hu, Lei Zhou, Qiaosheng Pu.  (2023)  Non-destructive distinction of single seed for Medicago sativa and Melilotus officinalis by capillary electrophoresis with laser-induced fluorescence detection.  JOURNAL OF CHROMATOGRAPHY A,  1704  (464116).  [PMID:37290349]
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16. Jie Li, Bingyong Mao, Xin Tang, Qiuxiang Zhang, Jianxin Zhao, Hao Zhang, Shumao Cui.  (2023)  Protective Effects of Naringenin and Apigenin in Ameliorating Skin Damage via Mediating the Nrf2 and NF-κB Pathways in Mice.  Foods,  12  (11): (2120).  [PMID:37297362]
17. Shaoyan Zhang, Jinfeng Ning, Qingqing Wang, Wei Wang.  (2023)  Fluorescence enhancement of flavonoids and its application in ingredient determination for some traditional Chinese medicines by CE-LIF.  Analytical Methods,  15  (24): (2964-2970).  [PMID:37309583]
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19. Xueyan Ji, Wei Du, Wenqing Che, Liping Wang, Lu Zhao.  (2023)  Apigenin Inhibits the Progression of Osteoarthritis by Mediating Macrophage Polarization.  MOLECULES,  28  (7): (2915).  [PMID:37049677]
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21. Jinying Guo, Chuanfa Gan, Bo Cheng, Bo Cui, Fankai Yi.  (2023)  Exploration of binding mechanism of apigenin to pepsin: Spectroscopic analysis, molecular docking, enzyme activity and antioxidant assays.  SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY,  290  (122281).  [PMID:36584639]
22. Mang-Mang Li, Yi-Ting Chen, Jin-Cang Ruan, Wen-Jun Wang, Ji-Guang Chen, Qing-Feng Zhang.  (2023)  Structure-activity relationship of dietary flavonoids on pancreatic lipase.  Current Research in Food Science,  (100424).  [PMID:36618100]
23. Fengxia Tang, Chuan Li, Xiaoran Yang, Jiandu Lei, Hongxia Chen, Changwei Zhang, Chengzhang Wang.  (2023)  Effect of Variety and Maturity Index on the Physicochemical Parameters Related to Virgin Olive Oil from Wudu (China).  Foods,  12  (1): (7).  [PMID:36613224]
24. Xijuan Tu, Fengjie Yu, Qian Jin, Chunping Du, Jiaxu Chen, Ji Yang, Yuchang He, Shaokang Huang, Wenbin Chen.  (2022)  A Simple High-Throughput Field Sample Preparation Method Based on Matrix-Induced Sugaring-Out for the Simultaneous Determination of 5-Hydroxymethylfurfural and Phenolic Compounds in Honey.  MOLECULES,  27  (23): (8373).  [PMID:36500464]
25. Fuqiang Liang, Yumeng Shi, Jiayi Shi, WeiWei Cao.  (2023)  Exploring the binding mechanism of pumpkin seed protein and apigenin: Spectroscopic analysis, molecular docking and molecular dynamics simulation.  FOOD HYDROCOLLOIDS,  137  (108318).  [PMID:]
26. Lingli Zhao, Mengfei Zheng, Hao Cai, Juan Chen, Yan Lin, Fangbin Wang, Lu Wang, Xian Zhang, Jian Liu.  (2023)  The activity comparison of six dietary flavonoids identifies that luteolin inhibits 3T3-L1 adipocyte differentiation through reducing ROS generation.  JOURNAL OF NUTRITIONAL BIOCHEMISTRY,  112  (109208).  [PMID:36370929]
27. Dan Yu, Fei Liu, Changdong Zou, Xiao Yang.  (2023)  Municipal green waste promotes iron release from steelmaking slag in water.  RESOURCES CONSERVATION AND RECYCLING,  188  (106722).  [PMID:]
28. Nabipour Hafezeh, Wang Xin, Song Lei, Hu Yuan.  (2022)  Intrinsically Anti-Flammable Apigenin-derived Epoxy Thermosets with High Glass Transition Temperature and Mechanical Strength.  CHINESE JOURNAL OF POLYMER SCIENCE,  40  (10): (1259-1268).  [PMID:]
29. Jia Gao, Qingyan Guo, Yan Yan, Chao Yu, Muning Chen, Wendong Xing, Li Yan, Yongsheng Yan, Yilin Wu.  (2022)  Templating precise multiple binding sites: Promising molecularly imprinted membrane orchestrated by sequential surface imprinting strategy.  CHEMICAL ENGINEERING JOURNAL,  450  (138058).  [PMID:]
30. Tingxuan Yan, Haili Wang, Xingfang Song, Tingyuan Yan, Yuwen Ding, Kang Luo, Juan Zhen, Gui He, Libin Nian, Shuangshou Wang, Zhixiang Wang.  (2022)  Fabrication of apigenin nanoparticles using antisolvent crystallization technology: A comparison of supercritical antisolvent, ultrasonic-assisted liquid antisolvent, and high-pressure homogenization technologies.  INTERNATIONAL JOURNAL OF PHARMACEUTICS,  624  (121981).  [PMID:35792228]
31. Ren Chuanhong, Guo Yan, Xie Linfeng, Zhao Zhikang, Xing Mengyun, Cao Yunlin, Liu Yilong, Lin Jing, Grierson Donald, Zhang Bo, Xu Changjie, Chen Kunsong, Li Xian.  (2022)  Identification of UDP-rhamnosyltransferases and UDP-galactosyltransferase involved in flavonol glycosylation in Morella rubra.  Horticulture Research,    [PMID:36072838]
32. Xiaoli Wang, Jichen Yang, Huan Li, Se Shi, Xin Peng.  (2022)  Mechanistic study and synergistic effect on inhibition of α-amylase by structurally similar flavonoids.  JOURNAL OF MOLECULAR LIQUIDS,  360  (119485).  [PMID:]
33. Dongxu Han, Yujie Yao, Lu Chen, Zhiying Miao, Shiwen Xu.  (2022)  Apigenin ameliorates di(2-ethylhexyl) phthalate-induced ferroptosis: The activation of glutathione peroxidase 4 and suppression of iron intake.  FOOD AND CHEMICAL TOXICOLOGY,  164  (113089).  [PMID:35500696]
34. Yihua Shi, Kai Lian, Jiguang Jia.  (2022)  Apigenin Suppresses the Warburg Effect and Stem-like Properties in SOSP-9607 Cells by Inactivating the PI3K/Akt/mTOR Signaling Pathway.  Evidence-based Complementary and Alternative Medicine,  2022  (3983637).  [PMID:35310040]
35. Fan Wu, Fulin Tian, Zhou Jin, Jing Liu, Weiping Jin, Xuan Chen, Zhan Wang, Xiwu Jia, Benguo Liu, Lingyi Liu, Wangyang Shen.  (2022)  Antioxidant capacities of heat-treated wheat germ and extruded compounded bran.  CEREAL CHEMISTRY,  99  (3): (582-592).  [PMID:]
36. Fuqiang Liang, Yumeng Shi, Weiwei Cao, Jiayi Shi.  (2022)  The inhibition mechanisms of pancreatic lipase by apigenin and its anti-obesity mechanisms revealed by using network pharmacology.  Food Bioscience,  45  (101515).  [PMID:]

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24. Fengxia Tang, Chuan Li, Xiaoran Yang, Jiandu Lei, Hongxia Chen, Changwei Zhang, Chengzhang Wang.  (2023)  Effect of Variety and Maturity Index on the Physicochemical Parameters Related to Virgin Olive Oil from Wudu (China).  Foods,  12  (1): (7).  [PMID:36613224]
25. Xijuan Tu, Fengjie Yu, Qian Jin, Chunping Du, Jiaxu Chen, Ji Yang, Yuchang He, Shaokang Huang, Wenbin Chen.  (2022)  A Simple High-Throughput Field Sample Preparation Method Based on Matrix-Induced Sugaring-Out for the Simultaneous Determination of 5-Hydroxymethylfurfural and Phenolic Compounds in Honey.  MOLECULES,  27  (23): (8373).  [PMID:36500464]
26. Fuqiang Liang, Yumeng Shi, Jiayi Shi, WeiWei Cao.  (2023)  Exploring the binding mechanism of pumpkin seed protein and apigenin: Spectroscopic analysis, molecular docking and molecular dynamics simulation.  FOOD HYDROCOLLOIDS,  137  (108318).  [PMID:]
27. Lingli Zhao, Mengfei Zheng, Hao Cai, Juan Chen, Yan Lin, Fangbin Wang, Lu Wang, Xian Zhang, Jian Liu.  (2023)  The activity comparison of six dietary flavonoids identifies that luteolin inhibits 3T3-L1 adipocyte differentiation through reducing ROS generation.  JOURNAL OF NUTRITIONAL BIOCHEMISTRY,  112  (109208).  [PMID:36370929]
28. Dan Yu, Fei Liu, Changdong Zou, Xiao Yang.  (2023)  Municipal green waste promotes iron release from steelmaking slag in water.  RESOURCES CONSERVATION AND RECYCLING,  188  (106722).  [PMID:]
29. Nabipour Hafezeh, Wang Xin, Song Lei, Hu Yuan.  (2022)  Intrinsically Anti-Flammable Apigenin-derived Epoxy Thermosets with High Glass Transition Temperature and Mechanical Strength.  CHINESE JOURNAL OF POLYMER SCIENCE,  40  (10): (1259-1268).  [PMID:]
30. Jia Gao, Qingyan Guo, Yan Yan, Chao Yu, Muning Chen, Wendong Xing, Li Yan, Yongsheng Yan, Yilin Wu.  (2022)  Templating precise multiple binding sites: Promising molecularly imprinted membrane orchestrated by sequential surface imprinting strategy.  CHEMICAL ENGINEERING JOURNAL,  450  (138058).  [PMID:]
31. Tingxuan Yan, Haili Wang, Xingfang Song, Tingyuan Yan, Yuwen Ding, Kang Luo, Juan Zhen, Gui He, Libin Nian, Shuangshou Wang, Zhixiang Wang.  (2022)  Fabrication of apigenin nanoparticles using antisolvent crystallization technology: A comparison of supercritical antisolvent, ultrasonic-assisted liquid antisolvent, and high-pressure homogenization technologies.  INTERNATIONAL JOURNAL OF PHARMACEUTICS,  624  (121981).  [PMID:35792228]
32. Ren Chuanhong, Guo Yan, Xie Linfeng, Zhao Zhikang, Xing Mengyun, Cao Yunlin, Liu Yilong, Lin Jing, Grierson Donald, Zhang Bo, Xu Changjie, Chen Kunsong, Li Xian.  (2022)  Identification of UDP-rhamnosyltransferases and UDP-galactosyltransferase involved in flavonol glycosylation in Morella rubra.  Horticulture Research,    [PMID:36072838]
33. Xiaoli Wang, Jichen Yang, Huan Li, Se Shi, Xin Peng.  (2022)  Mechanistic study and synergistic effect on inhibition of α-amylase by structurally similar flavonoids.  JOURNAL OF MOLECULAR LIQUIDS,  360  (119485).  [PMID:]
34. Dongxu Han, Yujie Yao, Lu Chen, Zhiying Miao, Shiwen Xu.  (2022)  Apigenin ameliorates di(2-ethylhexyl) phthalate-induced ferroptosis: The activation of glutathione peroxidase 4 and suppression of iron intake.  FOOD AND CHEMICAL TOXICOLOGY,  164  (113089).  [PMID:35500696]
35. Yihua Shi, Kai Lian, Jiguang Jia.  (2022)  Apigenin Suppresses the Warburg Effect and Stem-like Properties in SOSP-9607 Cells by Inactivating the PI3K/Akt/mTOR Signaling Pathway.  Evidence-based Complementary and Alternative Medicine,  2022  (3983637).  [PMID:35310040]
36. Fan Wu, Fulin Tian, Zhou Jin, Jing Liu, Weiping Jin, Xuan Chen, Zhan Wang, Xiwu Jia, Benguo Liu, Lingyi Liu, Wangyang Shen.  (2022)  Antioxidant capacities of heat-treated wheat germ and extruded compounded bran.  CEREAL CHEMISTRY,  99  (3): (582-592).  [PMID:]
37. Fuqiang Liang, Yumeng Shi, Weiwei Cao, Jiayi Shi.  (2022)  The inhibition mechanisms of pancreatic lipase by apigenin and its anti-obesity mechanisms revealed by using network pharmacology.  Food Bioscience,  45  (101515).  [PMID:]

Solution Calculators