Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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A607692-1mg | 1mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $84.90 | |
A607692-5mg | 5mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $185.90 | |
A607692-10mg | 10mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $279.90 | |
A607692-25mg | 25mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $519.90 | |
A607692-50mg | 50mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $729.90 | |
A607692-100mg | 100mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $1,089.90 |
Synonyms | CHEBI:76609 | N-(5-(4-Bromophenyl)-6-(2-((5-bromo-2-pyrimidinyl)oxy)ethoxy)-4-pyrimidinyl)sulfuric diamide | Sulfamide, N-(5-(4-bromophenyl)-6-(2-((5-bromo-2-pyrimidinyl)oxy)ethoxy)-4-pyrimidinyl)- | 1103522-45-7 | EX-A4419 | AC-36529 | AKOS028114466 | To |
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Specifications & Purity | Moligand™, ≥98% |
Storage Temp | Store at -20°C |
Shipped In | Ice chest + Ice pads |
Grade | Moligand™ |
Action Type | ANTAGONIST |
Mechanism of action | Endothelin receptor, ET-A/ET-B antagonist |
ALogP | 2.4 |
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Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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IUPAC Name | 5-(4-bromophenyl)-4-[2-(5-bromopyrimidin-2-yl)oxyethoxy]-6-(sulfamoylamino)pyrimidine |
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INCHI | InChI=1S/C16H14Br2N6O4S/c17-11-3-1-10(2-4-11)13-14(24-29(19,25)26)22-9-23-15(13)27-5-6-28-16-20-7-12(18)8-21-16/h1-4,7-9H,5-6H2,(H2,19,25,26)(H,22,23,24) |
InChi Key | DKULOVKANLVDEA-UHFFFAOYSA-N |
Canonical SMILES | C1=CC(=CC=C1C2=C(N=CN=C2OCCOC3=NC=C(C=N3)Br)NS(=O)(=O)N)Br |
Isomeric SMILES | C1=CC(=CC=C1C2=C(N=CN=C2OCCOC3=NC=C(C=N3)Br)NS(=O)(=O)N)Br |
Alternate CAS | 1103522-45-7 |
PubChem CID | 25099191 |
MeSH Entry Terms | ACT-132577;aprocitentan;N-(5-(4-Bromophenyl)-6-(2-((5-bromo-2-pyrimidinyl)oxy)ethoxy)-4-pyrimidinyl)sulfuric diamide;sulfamide, N-(5-(4-bromophenyl)-6-(2-((5-bromo-2-pyrimidinyl)oxy)ethoxy)-4-pyrimidinyl)- |
Molecular Weight | 546.19 |
PubChem CID | 25099191 |
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CAS Registry No. | 1103522-45-7 |
GPCRdb Ligand | aprocitentan |
Enter Lot Number to search for COA:
Find and download the COA for your product by matching the lot number on the packaging.
Lot Number | Certificate Type | Date | Item |
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F2405181 | Certificate of Analysis | Mar 02, 2024 | A607692 |
F2405182 | Certificate of Analysis | Mar 02, 2024 | A607692 |
F2405183 | Certificate of Analysis | Mar 02, 2024 | A607692 |
F2405184 | Certificate of Analysis | Mar 02, 2024 | A607692 |
F2405185 | Certificate of Analysis | Mar 02, 2024 | A607692 |
F2405186 | Certificate of Analysis | Mar 02, 2024 | A607692 |
F2405187 | Certificate of Analysis | Mar 02, 2024 | A607692 |
F2405188 | Certificate of Analysis | Mar 02, 2024 | A607692 |
F2405189 | Certificate of Analysis | Mar 02, 2024 | A607692 |
F2405190 | Certificate of Analysis | Mar 02, 2024 | A607692 |
F2405191 | Certificate of Analysis | Mar 02, 2024 | A607692 |
F2405192 | Certificate of Analysis | Mar 02, 2024 | A607692 |
1. Hao-Xiang Gao, Jie Yu, Nan Chen, Wei-Cai Zeng. (2020) Effects and mechanism of tea polyphenols on the quality of oil during frying process. JOURNAL OF FOOD SCIENCE, 85 (11): (3786-3796). [PMID:32990338] [10.1111/1750-3841.15470] |
1. Hao-Xiang Gao, Jie Yu, Nan Chen, Wei-Cai Zeng. (2020) Effects and mechanism of tea polyphenols on the quality of oil during frying process. JOURNAL OF FOOD SCIENCE, 85 (11): (3786-3796). [PMID:32990338] [10.1111/1750-3841.15470] |