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APY 29 - ≥98%(HPLC), high purity , CAS No.1216665-49-4

≥98%(HPLC)

CAS#: 1216665-49-4
Formula: C₁₇H₁₆N₈
Molecular Weight: 332.36
PubChem CID: 42627755

Item Number

A288548

Grouped product items
SKU	Size	Availability	Price
A288548-5mg	5mg	In stock	$73.90
A288548-10mg	10mg	In stock	$122.90
A288548-25mg	25mg	In stock	$276.90
A288548-50mg	50mg	In stock	$380.90
A288548-100mg	100mg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$682.90

Discover APY 29 by Aladdin Scientific in ≥98%(HPLC) for only $73.90. Available - in Ligands at Aladdin Scientific. Inhibits IRE1α autophosphorylation; activates IRE1α endoribonuclease activity Tags: .

Basic Description

Synonyms	(E)-N-(6-((5-cyclopropyl-1H-pyrazol-3-yl)imino)-1,6-dihydropyrimidin-2-yl)-1H-benzo[d]imidazol-6-amine;N2-1H-Benzimidazol-6-yl-N4-(5-cyclopropyl-1H-pyrazol-3-yl)-2,4-pyrimidinediamine;APY29 (type I kinase inhibitor);N2-(1H-Benzo[d]imidazol-6-yl)-N4-(3-cyc
Specifications & Purity	≥98%(HPLC)
Storage Temp	Store at -20°C
Shipped In	Dry ice
Product Description	Product Describtion: APY29 is considered as a type I kinase inhibitor of inositol requiring kinase enzyme 1 α (IRE1α).

Names and Identifiers

IUPAC Name	2-N-(3H-benzimidazol-5-yl)-4-N-(5-cyclopropyl-1H-pyrazol-3-yl)pyrimidine-2,4-diamine
INCHI	InChI=1S/C17H16N8/c1-2-10(1)13-8-16(25-24-13)22-15-5-6-18-17(23-15)21-11-3-4-12-14(7-11)20-9-19-12/h3-10H,1-2H2,(H,19,20)(H3,18,21,22,23,24,25)
InChi Key	WJNBSTLIALIIEW-UHFFFAOYSA-N
Canonical SMILES	C1CC1C2=CC(=NN2)NC3=NC(=NC=C3)NC4=CC5=C(C=C4)N=CN5
Isomeric SMILES	C1CC1C2=CC(=NN2)NC3=NC(=NC=C3)NC4=CC5=C(C=C4)N=CN5
PubChem CID	42627755
Molecular Weight	332.36

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5 results found

Lot Number	Certificate Type	Date	Item
B2218288	Certificate of Analysis	Jan 10, 2022	A288548
B2218292	Certificate of Analysis	Jan 10, 2022	A288548
B2218296	Certificate of Analysis	Jan 10, 2022	A288548
B2218297	Certificate of Analysis	Jan 10, 2022	A288548
B2218315	Certificate of Analysis	Jan 10, 2022	A288548

Solubility

Solvent:DMSO, Max Conc. mg/mL: 33.24, Max Conc. mM: 100; Solvent:1eq. HCl, Max Conc. mg/mL: 16.62, Max Conc. mM: 50

Melt Point(°C)

>280°C

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