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AR 420626 - ≥98%(HPLC), high purity , CAS No.1798310-55-0

≥98%(HPLC)

CAS#: 1798310-55-0
Formula: C₂₁H₁₈Cl₂N₂O₃
Molecular Weight: 417.29
PubChem CID: 91885415

Item Number

A287232

Grouped product items
SKU	Size	Availability	Price
A287232-5mg	5mg	In stock	$88.90
A287232-10mg	10mg	In stock	$147.90
A287232-25mg	25mg	In stock	$325.90
A287232-50mg	50mg	In stock	$523.90
A287232-100mg	100mg	In stock	$840.90
A287232-250mg	250mg	In stock	$1,892.90

FFA3 agonist

Basic Description

Synonyms	N-(2,5-Dichlorophenyl)-4-(furan-2-yl)-2-methyl-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carboxamide；AR420626
Specifications & Purity	≥98%(HPLC)
Biochemical and Physiological Mechanisms	FFA3 agonist (pEC50= 5.74). Inhibits nicotine and serotonin induced changes in motility of isolated muscle strips from rat colon. Also suppresses serotonin-induced fecal output in rats.
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads
Product Description	product description： AR420626 is a selective agonist of free fatty acid receptor 3 (FFAR3, GPR41) with IC50 of 117 nM. AR420626 inhibits nicotine and serotonin-induced changes in motility of isolated muscle strips from rat colon and suppresses serotonin-induced fecal output in rats。

Associated Targets(Human)

CACNA1C Tclin Voltage-gated L-type calcium channel alpha-1C subunit (766 Activities)

Discover Target: CACNA1C

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

FFAR1 Tchem Free fatty acid receptor 1 (4763 Activities)

Discover Target: FFAR1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

FFAR3 Tchem Free fatty acid receptor 3 (304 Activities)

Discover Target: FFAR3

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

FFAR2 Tchem Free fatty acid receptor 2 (545 Activities)

Discover Target: FFAR2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

FFAR4 Tchem G-protein coupled receptor 120 (2999 Activities)

Discover Target: FFAR4

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

GPR84 Tchem G-protein coupled receptor 84 (1284 Activities)

Discover Target: GPR84

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Names and Identifiers

IUPAC Name	N-(2,5-dichlorophenyl)-4-(furan-2-yl)-2-methyl-5-oxo-4,6,7,8-tetrahydro-1H-quinoline-3-carboxamide
INCHI	InChI=1S/C21H18Cl2N2O3/c1-11-18(21(27)25-15-10-12(22)7-8-13(15)23)20(17-6-3-9-28-17)19-14(24-11)4-2-5-16(19)26/h3,6-10,20,24H,2,4-5H2,1H3,(H,25,27)
InChi Key	GGTYQECCGLBHGS-UHFFFAOYSA-N
Canonical SMILES	CC1=C(C(C2=C(N1)CCCC2=O)C3=CC=CO3)C(=O)NC4=C(C=CC(=C4)Cl)Cl
Isomeric SMILES	CC1=C(C(C2=C(N1)CCCC2=O)C3=CC=CO3)C(=O)NC4=C(C=CC(=C4)Cl)Cl
PubChem CID	91885415
Molecular Weight	417.29

Certificates

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6 results found

Lot Number	Certificate Type	Date	Item
H2218183	Certificate of Analysis	Jun 02, 2022	A287232
H2218184	Certificate of Analysis	Jun 02, 2022	A287232
H2218185	Certificate of Analysis	Jun 02, 2022	A287232
H2218186	Certificate of Analysis	Jun 02, 2022	A287232
H2218188	Certificate of Analysis	Jun 02, 2022	A287232
H2218190	Certificate of Analysis	Jun 02, 2022	A287232

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