Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
---|
SKU | Size | Availability | Price | Qty |
---|---|---|---|---|
A111764-100mg | 100mg | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $149.90 | |
A111764-500mg | 500mg | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $439.90 | |
A111764-1g | 1g | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $699.90 |
ω-6 Polyunsaturated fatty acid, precursor of eicosanoids
Synonyms | ARA | 5,8,11,14-Eicosatetraenoic acid | C00219 | (5Z,8Z,11Z,14Z)-Icosatetraenoic acid | A0781 | Immunocytophyte | 5,8,11,14-Eicosatetraenoate | ARACHIDONIC ACID [INCI] | all-cis-eicosa-5,8,11,14-tetraenoic acid | HMS3402M21 | s6185 | UNII-27YG812J1I | [(2 |
---|---|
Specifications & Purity | Moligand™, analytical standard, ≥99%(GC) |
Biochemical and Physiological Mechanisms | Major precursor in the production of eicosanoids and important cellular signaling mediator. Endogenous free fatty acid released from phospholipids by PLA 2 . Metabolised by COX, lipoxygenase and cytochrome p450s to form a variety of eicosanoids |
Storage Temp | Protected from light,Store at -20°C,Argon charged |
Shipped In | Ice chest + Ice pads |
Grade | analytical standard, Moligand™ |
Action Type | ACTIVATOR, CHANNEL BLOCKER, INHIBITOR |
Mechanism of action | Activator of ClC-2;Activator of K 2P10.1;Activator of K 2P13.1;Inhibitor of K 2P18.1;Activator of K 2P2.1;Channel blocker of K 2P3.1;Activator of K 2P4.1;Activator of K ir2.3;Activator of K ir3.4;Channel blocker of K v4.2;Activator of protein kinase C zet |
Note | Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 6 months. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details. |
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
---|
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
---|
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
---|
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
---|
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
---|
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
---|
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
---|
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
---|
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
---|
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
---|
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
---|
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
---|
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
---|
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
---|
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
---|
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
---|
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
---|
Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
---|
Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
---|
Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
---|
Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
---|
Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
---|
Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
---|
Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
---|
Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
---|
Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
---|
Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
---|
Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
---|
Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
---|
Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
---|
Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
---|
Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
---|
Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
---|
Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
---|
Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
---|
Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
---|
Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
---|
Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
---|
Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
---|
Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
---|
Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
---|
Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
---|
Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
---|
Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
---|
Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
---|
Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
---|
Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
---|
Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
---|
Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
---|
Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
---|
Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
---|
Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
---|
Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
---|
Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
---|
Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
---|
Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
---|
Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
---|
Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
---|
Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
---|
Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
---|
Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
---|
Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
---|
Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
---|
Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
---|
Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
---|
Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
---|
Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
---|
Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
---|
Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
---|
Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
---|
Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
---|
Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
---|
Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
---|
Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
---|
Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
---|
Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
---|
Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
---|
Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
---|
Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
---|
Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
---|
Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
---|
Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
---|
IUPAC Name | (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoic acid |
---|---|
INCHI | InChI=1S/C20H32O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20(21)22/h6-7,9-10,12-13,15-16H,2-5,8,11,14,17-19H2,1H3,(H,21,22)/b7-6-,10-9-,13-12-,16-15- |
InChi Key | YZXBAPSDXZZRGB-DOFZRALJSA-N |
Canonical SMILES | CCCCCC=CCC=CCC=CCC=CCCCC(=O)O |
Isomeric SMILES | CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(=O)O |
PubChem CID | 444899 |
Molecular Weight | 304.47 |
Beilstein | 1713889 |
PubChem CID | 444899 |
---|---|
ChEBI | CHEBI:15843 |
Wikipedia | Arachidonic_acid |
ChEMBL Ligand | CHEMBL15594 |
DrugBank Ligand | DB04557 |
CAS Registry No. | 506-32-1 |
RCSB PDB Ligand | ACD |
Antibiotic DB | 1427 |
Enter Lot Number to search for COA:
Find and download the COA for your product by matching the lot number on the packaging.
Lot Number | Certificate Type | Date | Item |
---|---|---|---|
D2213001 | Certificate of Analysis | Jan 08, 2024 | A111764 |
K2117724 | Certificate of Analysis | Aug 09, 2023 | A111764 |
D2313873 | Certificate of Analysis | Jan 10, 2023 | A111764 |
D2314277 | Certificate of Analysis | Jan 10, 2023 | A111764 |
D2314278 | Certificate of Analysis | Jan 10, 2023 | A111764 |
K2217074 | Certificate of Analysis | Nov 03, 2022 | A111764 |
K2217075 | Certificate of Analysis | Nov 03, 2022 | A111764 |
D2213002 | Certificate of Analysis | Mar 26, 2022 | A111764 |
D2213003 | Certificate of Analysis | Mar 26, 2022 | A111764 |
Sensitivity | Air & Moisture and Light Sensitive |
---|---|
Refractive Index | 1.4872 |
Flash Point(°F) | 113 °C |
Flash Point(°C) | 113°C |
Boil Point(°C) | 169-171 °C/0.15 mmHg |
Melt Point(°C) | -49°C |
Pictogram(s) | GHS07 |
---|---|
Signal | Warning |
Hazard Statements | H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation H302:Harmful if swallowed H312:Harmful in contact with skin H332:Harmful if inhaled |
Precautionary Statements | P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P271:Use only outdoors or in a well-ventilated area. P270:Do not eat, drink or smoke when using this product. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P362+P364:Take off contaminated clothing and wash it before reuse. P330:Rinse mouth. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P301+P317:IF SWALLOWED: Get medical help. P317:Get emergency medical help. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. P319:Get medical help if you feel unwell. |
Merck Index | 765 |
1. Xiangxin Xu, Xiaofang Liu, Shuai Wang, Yongping Zou, Jixian Zhang, Li Liang, Chaoting Wen, Youdong Li, Xiaowei Xu, Xudong He, Guoyan Liu, Xin Xu. (2024) Relationship between PAH4 formation and thermal reaction products in model lipids and possible pathways of PAHs formation. JOURNAL OF HAZARDOUS MATERIALS, 465 (133374). [PMID:38160552] |
2. Qiyue Wang, Tao Wang, Shengfei Yang, Hui Du, Bo Zhang, Sirui Cui, Daishun Ling, Fangyuan Li. (2023) Highly Sensitive Diagnosis of Extracellular Calcium Ions Associated Brain Diseases using Ca2+-Dependent T2-T1 Switchable Magnetic Nanosensors. ADVANCED FUNCTIONAL MATERIALS, (2313286). [PMID:] |
3. Chen Song, Fanxuan Kong, Huijia Nong, Liu Cai, Ye Tian, Honghao Hou, Leyu Wang, Xiaozhong Qiu. (2023) Ammonium Persulfate-Loaded Carboxylic Gelatin–Methacrylate Nanoparticles Promote Cardiac Repair by Activating Epicardial Epithelial–Mesenchymal Transition via Autophagy and the mTOR Pathway. ACS Nano, (12): [PMID:37782701] |
4. Jiaqi Cui, Jianxun Zhang, Shihao Sun, Wu Fan, Hui Xi, Xiujuan Xu, Lingbo Ji, Shusheng Zhang, Dingzhong Wang, Wuduo Zhao. (2023) Rapid and sensitive determination of free fatty acids based on in-source microdroplet-driven derivatization coupled with high-resolution mass spectrometry. ANALYTICA CHIMICA ACTA, 1278 (341717). [PMID:37709460] |
5. Jia Liu, Peng Sun, Xiaole Qi. (2023) Reversible and Non-Competitive Inhibition of Cyclooxygenase by Indobufen for Efficient Antiplatelet Action and Relief of Gastrointestinal Irritation. Pharmaceutics, 15 (8): (2135). [PMID:37631348] |
6. Li Li, Wenfang Jin, Yue Wang, Li Yang, Zhi-Feng Zhang. (2023) Study on Chemical Constituents of the Enriched Extracts of Erigeron multiradiatus and Anti-thrombotic Effect on Zebrafish. Pharmacognosy Magazine, [PMID:] |
7. Wen Liu, Min Zhu, Meng Gong, Wen Zheng, Xin Zeng, Qing Zheng, Xiaoyu Li, Fudong Fu, Yingyi Chen, Jingqiu Cheng, Zhiyong Rao, Yanrong Lu, Younan Chen. (2023) Comparison of the Effects of Monounsaturated Fatty Acids and Polyunsaturated Fatty Acids on Liver Lipid Disorders in Obese Mice. Nutrients, 15 (14): (3200). [PMID:37513618] |
8. Xiaoting Luo, Feifei Lu, Zhiyue Yin, Zhiyun Zhou, Zhongmin Wang, Hongjian Zhang. (2023) Hormetic effects of EGC and EGCG on CES1 activity and its rescue from oxidative stress in rat liver S9. CHEMICO-BIOLOGICAL INTERACTIONS, 382 (110612). [PMID:37353134] |
9. Jinmiao Tian, Lichao Zhang, Xiaoqin La, Xiaxia Fan, Aiping Li, Changxin Wu, Yuxuan An, Shuning Yan, Xiushan Dong, Haitao Wu, Zhuoyu Li. (2023) Tumor-secreted GRP78 induces M2 polarization of macrophages by promoting lipid catabolism. CELLULAR SIGNALLING, 108 (110719). [PMID:37207940] |
10. Jie Cheng, Yuling Li, Yunjun Wang, Jing Zhang, Tuanqi Sun, Li Zhang, Yinlong Guo. (2022) Quaterization Derivatization with Bis(Pyridine) Iodine Tetrafluoroboride: High-Sensitivity Mass Spectrometric Analysis of Unsaturated Fatty Acids in Human Thyroid Tissues. ANALYTICAL CHEMISTRY, 94 (32): (11185–11191). [PMID:35916214] |
11. Xin-jie Cheng, De-zhi Kong, Ya-hui Li, Guang-li Bian, De-qiang Li. (2022) Screening of dual targeted inhibitors of 5-lipoxygenase and cyclooxygenase-2 from Oroxylum indicum by off-line two-dimensional liquid chromatography coupled with mass spectrometry. INDUSTRIAL CROPS AND PRODUCTS, 186 (115243). [PMID:] |
12. Changli Zhang, Nan Li, Zhongyao Wang, Shihan Wang, Zhihan Wang, Xuanrui Fan, Xinxin Xu, Yue Zhou, Yongsheng Wang. (2022) Unsaturated fatty-acid based HPLC fingerprints in combination with quantitative analysis of multi-components by single-marker for the classification of Rana chensinensis ovum. NEW JOURNAL OF CHEMISTRY, 46 (21): (10441-10450). [PMID:] |
13. Lan Zhenwei, Zhang Ying, Sun Yue, Wang Lvhong, Huang Yuting, Cao Hui, Wang Shumei, Meng Jiang. (2021) Identifying of Anti-Thrombin Active Components From Curcumae Rhizoma by Affinity-Ultrafiltration Coupled With UPLC-Q-Exactive Orbitrap/MS. Frontiers in Pharmacology, 12 [PMID:34955839] |
14. Yuan Zhou, Mengying Wei, Meiling Fan, Zhongying Liu, Aimin Wang, Yuanyuan Liu, Lihui Men, Zifeng Pi, Zhiqiang Liu, Fengrui Song. (2021) Pharmacokinetic and metabolomics approach based on UHPLC-MS to evaluate therapeutic effect of lignans from S. Chinensis in alzheimer's disease. JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 1178 (122859). [PMID:34274605] |
15. Lu Chen, Minxia Song, Jie Guan, Yun Shu, Dangqin Jin, Gaochao Fan, Qin Xu, Xiao-Ya Hu. (2021) A highly-specific photoelectrochemical platform based on carbon nanodots and polymers functionalized organic-inorganic perovskite for cholesterol sensing. TALANTA, 225 (122050). [PMID:33592772] |
16. Leilei Yang, Jingjing Liang, Sin Man Lam, Ahmet Yavuz, Guanghou Shui, Mei Ding, Xun Huang. (2020) Neuronal lipolysis participates in PUFA-mediated neural function and neurodegeneration. EMBO REPORTS, 21 (11): (e50214). [PMID:33034119] |
17. Liu Tengwen, Guo Yuhong, Zhao Jingxia, He Shasha, Bai Yunjing, Wang Ning, Lin Yan, Liu Qingquan, Xu Xiaolong. (2020) Systems Pharmacology and Verification of ShenFuHuang Formula in Zebrafish Model Reveal Multi-Scale Treatment Strategy for Septic Syndrome in COVID-19. Frontiers in Pharmacology, 11 [PMID:33041827] |
18. Yumeng Yang, Dan Gao, Rui Qian, Yuyang Jiang. (2020) Polydopamine-Modified TS-1 Zeolite Framework Nanoparticles as a Matrix for the Analysis of Small Molecules by MALDI-TOF MS. ACS Omega, 5 (32): (19952–19959). [PMID:32832749] |
19. Yong-ping Shi, You-gang Zhang, Hao-nan Li, Hao-tian Kong, Shan-shan Zhang, Xuan-ming Zhang, Xiao-bin Li, Ke-chun Liu, Li-wen Han, Qing-ping Tian. (2020) Discovery and identification of antithrombotic chemical markers in Gardenia Fructus by herbal metabolomics and zebrafish model. JOURNAL OF ETHNOPHARMACOLOGY, 253 (112679). [PMID:32101773] |
20. Mengying Wei, Zhongying Liu, Yuanyuan Liu, Shizhe Li, Mingxin Hu, Kexin Yue, Tianshu Liu, Yang He, Zifeng Pi, Zhiqiang Liu, Fengrui Song. (2019) Urinary and plasmatic metabolomics strategy to explore the holistic mechanism of lignans in S. chinensis in treating Alzheimer's disease using UPLC-Q-TOF-MS. Food & Function, 10 (9): (5656-5668). [PMID:31433414] |
21. Mengying Wei, Yuanyuan Liu, Zifeng Pi, Kexin Yue, Shizhe Li, Mingxin Hu, Zhiqiang Liu, Fengrui Song, Zhongying Liu. (2019) Investigation of plasma metabolomics and neurotransmitter dysfunction in the process of Alzheimer's disease rat induced by amyloid beta 25-35. RSC Advances, 9 (32): (18308-18319). [PMID:35515227] |
22. Jing Tan, Cuizhu Wang, Hailin Zhu, Baisong Zhou, Lingxin Xiong, Fang Wang, Pingya Li, Jinping Liu. (2018) Comprehensive Metabolomics Analysis of Xueshuan Xinmaining Tablet in Blood Stasis Model Rats Using UPLC-Q/TOF-MS. MOLECULES, 23 (7): (1650). [PMID:29986394] |
23. Song Chen, Wang Leyu, Ye Genlan, Song Xiaoping, He Yutong, Qiu Xiaozhong. (2017) Residual Ammonium Persulfate in Nanoparticles Has Cytotoxic Effects on Cells through Epithelial-Mesenchymal Transition. Scientific Reports, 7 (1): (1-12). [PMID:28924225] |
24. Minjian Chen, Bin Xu, Wenliang Ji, Shanlei Qiao, Nan Hu, Yanhui Hu, Wei Wu, Lianglin Qiu, Ruyang Zhang, Yubang Wang, Shoulin Wang, Zuomin Zhou, Yankai Xia, Xinru Wang. (2012) Bisphenol A Alters n-6 Fatty Acid Composition and Decreases Antioxidant Enzyme Levels in Rat Testes: A LC-QTOF-Based Metabolomics Study. PLoS One, 7 (9): (e44754). [PMID:23024759] |
25. Zhang X et al.. (2019) Metabolomics for Biomarker Discovery in Fermented Black Garlic and Potential Bioprotective Responses against Cardiovascular Diseases.. J Agric Food Chem, 67 (44): (12191-12198). [PMID:31588747] |
1. Beavers WN, Monteith AJ, Amarnath V, Mernaugh RL, Roberts 2nd LJ, Chazin WJ, Davies SS, Skaar EP. (2019) Arachidonic Acid Kills Staphylococcus aureus through a Lipid Peroxidation Mechanism.. mBio, 10 (5): (1755-70). [PMID:31575763] |
2. Cantonero C et al.. (2020) Arachidonic Acid Attenuates Cell Proliferation, Migration and Viability by a Mechanism Independent on Calcium Entry.. Int J Mol Sci, 21 (9): [PMID:32392840] |
3. Ye Z et al.. (2021) Arachidonic acid-regulated calcium signaling in T cells from patients with rheumatoid arthritis promotes synovial inflammation.. Nat Commun, 12 (907). [PMID:33568645] |
4. Díaz-Viraqué F et al.. (2018) Old Yellow Enzyme from Trypanosoma cruzi Exhibits In Vivo Prostaglandin F2a Synthase Activity and Has a Key Role in Parasite Infection and Drug Susceptibility.. Front Immunol, 9 (456). [PMID:29563916] |
5. Xiangxin Xu, Xiaofang Liu, Shuai Wang, Yongping Zou, Jixian Zhang, Li Liang, Chaoting Wen, Youdong Li, Xiaowei Xu, Xudong He, Guoyan Liu, Xin Xu. (2024) Relationship between PAH4 formation and thermal reaction products in model lipids and possible pathways of PAHs formation. JOURNAL OF HAZARDOUS MATERIALS, 465 (133374). [PMID:38160552] |
6. Qiyue Wang, Tao Wang, Shengfei Yang, Hui Du, Bo Zhang, Sirui Cui, Daishun Ling, Fangyuan Li. (2023) Highly Sensitive Diagnosis of Extracellular Calcium Ions Associated Brain Diseases using Ca2+-Dependent T2-T1 Switchable Magnetic Nanosensors. ADVANCED FUNCTIONAL MATERIALS, (2313286). [PMID:] |
7. Chen Song, Fanxuan Kong, Huijia Nong, Liu Cai, Ye Tian, Honghao Hou, Leyu Wang, Xiaozhong Qiu. (2023) Ammonium Persulfate-Loaded Carboxylic Gelatin–Methacrylate Nanoparticles Promote Cardiac Repair by Activating Epicardial Epithelial–Mesenchymal Transition via Autophagy and the mTOR Pathway. ACS Nano, (12): [PMID:37782701] |
8. Jiaqi Cui, Jianxun Zhang, Shihao Sun, Wu Fan, Hui Xi, Xiujuan Xu, Lingbo Ji, Shusheng Zhang, Dingzhong Wang, Wuduo Zhao. (2023) Rapid and sensitive determination of free fatty acids based on in-source microdroplet-driven derivatization coupled with high-resolution mass spectrometry. ANALYTICA CHIMICA ACTA, 1278 (341717). [PMID:37709460] |
9. Jia Liu, Peng Sun, Xiaole Qi. (2023) Reversible and Non-Competitive Inhibition of Cyclooxygenase by Indobufen for Efficient Antiplatelet Action and Relief of Gastrointestinal Irritation. Pharmaceutics, 15 (8): (2135). [PMID:37631348] |
10. Li Li, Wenfang Jin, Yue Wang, Li Yang, Zhi-Feng Zhang. (2023) Study on Chemical Constituents of the Enriched Extracts of Erigeron multiradiatus and Anti-thrombotic Effect on Zebrafish. Pharmacognosy Magazine, [PMID:] |
11. Wen Liu, Min Zhu, Meng Gong, Wen Zheng, Xin Zeng, Qing Zheng, Xiaoyu Li, Fudong Fu, Yingyi Chen, Jingqiu Cheng, Zhiyong Rao, Yanrong Lu, Younan Chen. (2023) Comparison of the Effects of Monounsaturated Fatty Acids and Polyunsaturated Fatty Acids on Liver Lipid Disorders in Obese Mice. Nutrients, 15 (14): (3200). [PMID:37513618] |
12. Xiaoting Luo, Feifei Lu, Zhiyue Yin, Zhiyun Zhou, Zhongmin Wang, Hongjian Zhang. (2023) Hormetic effects of EGC and EGCG on CES1 activity and its rescue from oxidative stress in rat liver S9. CHEMICO-BIOLOGICAL INTERACTIONS, 382 (110612). [PMID:37353134] |
13. Jinmiao Tian, Lichao Zhang, Xiaoqin La, Xiaxia Fan, Aiping Li, Changxin Wu, Yuxuan An, Shuning Yan, Xiushan Dong, Haitao Wu, Zhuoyu Li. (2023) Tumor-secreted GRP78 induces M2 polarization of macrophages by promoting lipid catabolism. CELLULAR SIGNALLING, 108 (110719). [PMID:37207940] |
14. Jie Cheng, Yuling Li, Yunjun Wang, Jing Zhang, Tuanqi Sun, Li Zhang, Yinlong Guo. (2022) Quaterization Derivatization with Bis(Pyridine) Iodine Tetrafluoroboride: High-Sensitivity Mass Spectrometric Analysis of Unsaturated Fatty Acids in Human Thyroid Tissues. ANALYTICAL CHEMISTRY, 94 (32): (11185–11191). [PMID:35916214] |
15. Xin-jie Cheng, De-zhi Kong, Ya-hui Li, Guang-li Bian, De-qiang Li. (2022) Screening of dual targeted inhibitors of 5-lipoxygenase and cyclooxygenase-2 from Oroxylum indicum by off-line two-dimensional liquid chromatography coupled with mass spectrometry. INDUSTRIAL CROPS AND PRODUCTS, 186 (115243). [PMID:] |
16. Changli Zhang, Nan Li, Zhongyao Wang, Shihan Wang, Zhihan Wang, Xuanrui Fan, Xinxin Xu, Yue Zhou, Yongsheng Wang. (2022) Unsaturated fatty-acid based HPLC fingerprints in combination with quantitative analysis of multi-components by single-marker for the classification of Rana chensinensis ovum. NEW JOURNAL OF CHEMISTRY, 46 (21): (10441-10450). [PMID:] |
17. Lan Zhenwei, Zhang Ying, Sun Yue, Wang Lvhong, Huang Yuting, Cao Hui, Wang Shumei, Meng Jiang. (2021) Identifying of Anti-Thrombin Active Components From Curcumae Rhizoma by Affinity-Ultrafiltration Coupled With UPLC-Q-Exactive Orbitrap/MS. Frontiers in Pharmacology, 12 [PMID:34955839] |
18. Yuan Zhou, Mengying Wei, Meiling Fan, Zhongying Liu, Aimin Wang, Yuanyuan Liu, Lihui Men, Zifeng Pi, Zhiqiang Liu, Fengrui Song. (2021) Pharmacokinetic and metabolomics approach based on UHPLC-MS to evaluate therapeutic effect of lignans from S. Chinensis in alzheimer's disease. JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 1178 (122859). [PMID:34274605] |
19. Lu Chen, Minxia Song, Jie Guan, Yun Shu, Dangqin Jin, Gaochao Fan, Qin Xu, Xiao-Ya Hu. (2021) A highly-specific photoelectrochemical platform based on carbon nanodots and polymers functionalized organic-inorganic perovskite for cholesterol sensing. TALANTA, 225 (122050). [PMID:33592772] |
20. Leilei Yang, Jingjing Liang, Sin Man Lam, Ahmet Yavuz, Guanghou Shui, Mei Ding, Xun Huang. (2020) Neuronal lipolysis participates in PUFA-mediated neural function and neurodegeneration. EMBO REPORTS, 21 (11): (e50214). [PMID:33034119] |
21. Liu Tengwen, Guo Yuhong, Zhao Jingxia, He Shasha, Bai Yunjing, Wang Ning, Lin Yan, Liu Qingquan, Xu Xiaolong. (2020) Systems Pharmacology and Verification of ShenFuHuang Formula in Zebrafish Model Reveal Multi-Scale Treatment Strategy for Septic Syndrome in COVID-19. Frontiers in Pharmacology, 11 [PMID:33041827] |
22. Yumeng Yang, Dan Gao, Rui Qian, Yuyang Jiang. (2020) Polydopamine-Modified TS-1 Zeolite Framework Nanoparticles as a Matrix for the Analysis of Small Molecules by MALDI-TOF MS. ACS Omega, 5 (32): (19952–19959). [PMID:32832749] |
23. Yong-ping Shi, You-gang Zhang, Hao-nan Li, Hao-tian Kong, Shan-shan Zhang, Xuan-ming Zhang, Xiao-bin Li, Ke-chun Liu, Li-wen Han, Qing-ping Tian. (2020) Discovery and identification of antithrombotic chemical markers in Gardenia Fructus by herbal metabolomics and zebrafish model. JOURNAL OF ETHNOPHARMACOLOGY, 253 (112679). [PMID:32101773] |
24. Mengying Wei, Zhongying Liu, Yuanyuan Liu, Shizhe Li, Mingxin Hu, Kexin Yue, Tianshu Liu, Yang He, Zifeng Pi, Zhiqiang Liu, Fengrui Song. (2019) Urinary and plasmatic metabolomics strategy to explore the holistic mechanism of lignans in S. chinensis in treating Alzheimer's disease using UPLC-Q-TOF-MS. Food & Function, 10 (9): (5656-5668). [PMID:31433414] |
25. Mengying Wei, Yuanyuan Liu, Zifeng Pi, Kexin Yue, Shizhe Li, Mingxin Hu, Zhiqiang Liu, Fengrui Song, Zhongying Liu. (2019) Investigation of plasma metabolomics and neurotransmitter dysfunction in the process of Alzheimer's disease rat induced by amyloid beta 25-35. RSC Advances, 9 (32): (18308-18319). [PMID:35515227] |
26. Jing Tan, Cuizhu Wang, Hailin Zhu, Baisong Zhou, Lingxin Xiong, Fang Wang, Pingya Li, Jinping Liu. (2018) Comprehensive Metabolomics Analysis of Xueshuan Xinmaining Tablet in Blood Stasis Model Rats Using UPLC-Q/TOF-MS. MOLECULES, 23 (7): (1650). [PMID:29986394] |
27. Song Chen, Wang Leyu, Ye Genlan, Song Xiaoping, He Yutong, Qiu Xiaozhong. (2017) Residual Ammonium Persulfate in Nanoparticles Has Cytotoxic Effects on Cells through Epithelial-Mesenchymal Transition. Scientific Reports, 7 (1): (1-12). [PMID:28924225] |
28. Minjian Chen, Bin Xu, Wenliang Ji, Shanlei Qiao, Nan Hu, Yanhui Hu, Wei Wu, Lianglin Qiu, Ruyang Zhang, Yubang Wang, Shoulin Wang, Zuomin Zhou, Yankai Xia, Xinru Wang. (2012) Bisphenol A Alters n-6 Fatty Acid Composition and Decreases Antioxidant Enzyme Levels in Rat Testes: A LC-QTOF-Based Metabolomics Study. PLoS One, 7 (9): (e44754). [PMID:23024759] |
29. Zhang X et al.. (2019) Metabolomics for Biomarker Discovery in Fermented Black Garlic and Potential Bioprotective Responses against Cardiovascular Diseases.. J Agric Food Chem, 67 (44): (12191-12198). [PMID:31588747] |