Arg-AMS - 10mM in DMSO, high purity , CAS No.301351-95-1(DMSO)

  • 10mM in DMSO
Item Number
A655716
Grouped product items
SKUSizeAvailabilityPrice Qty
A655716-1ml
1ml
Available within 8-12 weeks(?)
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$605.90

Basic Description

Specifications & Purity10mM in DMSO
Biochemical and Physiological MechanismsArg-AMS (compound 24) is a potent nanomolar inhibitor of arginyl tRNA synthetase , which displays tightly bound inhibitory characteristics for the A-domains in non-ribosomal peptide synthetases (NRPS) enzymes.
Storage TempStore at -80°C
Shipped InIce chest + Ice pads
Product Description

Arg-AMS (compound 24) is a potent nanomolar inhibitor of arginyl tRNA synthetase , which displays tightly bound inhibitory characteristics for the A-domains in non-ribosomal peptide synthetases (NRPS) enzymes.

In Vitro

Arg-AMS inhibits the Orn-activating domain of GrsB with an IC 50 value of 4.6 µM. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Associated Targets(Human)

RARS Tchem Arginine--tRNA ligase, cytoplasmic (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Names and Identifiers

Canonical SMILES C1=NC(=C2C(=N1)N(C=N2)C3C(C(C(O3)COS(=O)(=O)NC(=O)C(CCCN=C(N)N)N)O)O)N
Molecular Weight 502.51

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