Basic Description

Synonyms	Aristololactam \| 8-methoxy-[1,3]dioxolo[4',5':4,5]benzo[1,2,3-cd]benzo[f]indol-5(6H)-one \| UNII-3G8CFM4T9A \| Aristololactam; Aristolactam \| Benzo[f]-1,3-benzodioxolo[6,5,4-cd]indol-5(6H)-one, 8-methoxy- \| Q-100130 \| UNII-43DWT87QT7 \| Benzo(f)-1,3-benzodio
Specifications & Purity	analytical reference
Storage Temp	Store at 2-8°C,Protected from light,Desiccated
Shipped In	Wet ice
Grade	analytical reference

Associated Targets(Human)

CDK2 Tchem Cyclin-dependent kinase 2 (0 Activities)

Discover Target: CDK2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

CDK2 Tchem Cyclin-dependent kinase 2 (9050 Activities)

Discover Target: CDK2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Associated Targets(non-human)

P388 (20296 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mechanisms of Action

Mechanism of Action	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	References

Names and Identifiers

IUPAC Name	14-methoxy-3,5-dioxa-10-azapentacyclo[9.7.1.02,6.08,19.013,18]nonadeca-1(18),2(6),7,11(19),12,14,16-heptaen-9-one
INCHI	InChI=1S/C17H11NO4/c1-20-12-4-2-3-8-9(12)5-11-14-10(17(19)18-11)6-13-16(15(8)14)22-7-21-13/h2-6H,7H2,1H3,(H,18,19)
InChi Key	MXOKGWUJNGEKBH-UHFFFAOYSA-N
Canonical SMILES	COC1=CC=CC2=C3C4=C(C=C21)NC(=O)C4=CC5=C3OCO5
Isomeric SMILES	COC1=CC=CC2=C3C4=C(C=C21)NC(=O)C4=CC5=C3OCO5
PubChem CID	96710
Molecular Weight	293.27

Certificates

Certificate of Analysis(COA)

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2 results found

Lot Number	Certificate Type	Date	Item
I2101205	Certificate of Analysis	Jun 04, 2024	A302423
I2101206	Certificate of Analysis	Jun 04, 2024	A302423

Chemical and Physical Properties

Flash Point(°C)	234.4±25.7 °C
Boil Point(°C)	463.9±34.0 °C(Predicted)
Melt Point(°C)	319 °C

Safety and Hazards(GHS)

Pictogram(s)	GHS06, GHS08
Signal	Danger
Hazard Statements	H341:Suspected of causing genetic defects H351:Suspected of causing cancer H300:Fatal if swallowed H310:Fatal in contact with skin H330:Fatal if inhaled
Precautionary Statements	P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P260:Do not breathe dust/fume/gas/mist/vapors/spray. P284:[In case of inadequate ventilation] Wear respiratory protection. P281:Use personal protective equipment as required. P271:Use only outdoors or in a well-ventilated area. P270:Do not eat, drink or smoke when using this product. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P330:Rinse mouth. P262:Do not get in eyes, on skin, or on clothing. P320:Specific treatment is urgent (see ... on this label). P361+P364:Take off immediately all contaminated clothing and wash it before reuse. P203:Obtain, read and follow all safety instructions before use. P301+P316:IF SWALLOWED: Get emergency medical help immediately. P318:if exposed or concerned, get medical advice. P316:Get emergency medical help immediately.

FAQs and Articles

FAQ

JAK-STAT Cell Signaling Pathway

Categories: Technical articles

Tags:

treat tumors leukemia JAK family kinases

Solution Calculators

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SKU	Size	Availability	Price	Qty
A302423-5mg	5mg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$481.90
A302423-20mg	20mg	In stock	$1,374.90

Aristolactam I - Analytical reference, high purity , CAS No.13395-02-3