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Arteether - ≥97%, high purity , CAS No.75887-54-6

  • Moligand™
  • ≥97%
Item Number
A304568
Grouped product items
SKUSizeAvailabilityPrice Qty
A304568-25mg
25mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$156.90
A304568-100mg
100mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$521.90
View related series
Parasite

Basic Description

SynonymsArteether|Artemotil|75887-54-6|Beta-Arteether|SM-227|NSC-665971|(3R,5aS,6R,8aS,9R,10S,12R,12aR)-10-Ethoxydecahydro-3,6,9-trimethyl-3,12-epoxy-12H-pyrano(4,3-j)-1,2-benzodioxepin|beta-Dihydroartemisinin ethyl ether|(1R,4S,5R,8S,9R,10S,12R,13R)-10-ethoxy-1,
Specifications & PurityMoligand™, ≥97%
Storage TempStore at -20°C
Shipped InIce chest + Ice pads
GradeMoligand™
Product Description

Artemotil( β- Artether has anti malarial activity and can be used to study Plasmodium falciparum resistant Plasmodium falciparum malaria, with an IC50 value of 1.61 nM. Artemotiltil exhibits CNS neurotoxicity and anorexia toxicity in rats, dogs, and monkeys.

Product Properties

ALogP3.4

Associated Targets

CYP1A2 Tchem Cytochrome P450 1A2 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

HDAC6 Tclin Histone deacetylase 6 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Names and Identifiers

IUPAC Name (1R,4S,5R,8S,9R,10S,12R,13R)-10-ethoxy-1,5,9-trimethyl-11,14,15,16-tetraoxatetracyclo[10.3.1.04,13.08,13]hexadecane
INCHI InChI=1S/C17H28O5/c1-5-18-14-11(3)13-7-6-10(2)12-8-9-16(4)20-15(19-14)17(12,13)22-21-16/h10-15H,5-9H2,1-4H3/t10-,11-,12+,13+,14+,15-,16-,17-/m1/s1
InChi Key NLYNIRQVMRLPIQ-XQLAAWPRSA-N
Canonical SMILES CCOC1C(C2CCC(C3C24C(O1)OC(CC3)(OO4)C)C)C
Isomeric SMILES CCO[C@@H]1[C@@H]([C@@H]2CC[C@H]([C@H]3[C@]24[C@H](O1)O[C@@](CC3)(OO4)C)C)C
PubChem CID 3000469
Molecular Weight 312.40

Certificates

Certificate of Analysis(COA)

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Chemical and Physical Properties

Specific Rotation[α][α]/D +148 to +165°, c = 1 in chloroform-d
Flash Point(°C)146℃
Boil Point(°C)372.4℃ at 760 mmHg
Melt Point(°C)80-82°C

Related Documents

Solution Calculators