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Arteether - ≥97%, high purity , CAS No.75887-54-6
Basic Description Synonyms β-Arteether | (+)-Arteether | (3R,5aS,6R,8aS,9R,10S,12R,12aR)-10-Ethoxydecahydro-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin | Dihydroartemisinin ethyl ether Specifications & Purity Moligand™, ≥97% Storage Temp Store at -20°C Shipped In Ice chest + Ice pads Grade Moligand™ Product Description Artemotil（ β- Artether has anti malarial activity and can be used to study Plasmodium falciparum resistant Plasmodium falciparum malaria, with an IC50 value of 1.61 nM. Artemotiltil exhibits CNS neurotoxicity and anorexia toxicity in rats, dogs, and monkeys.
Associated Targets(Human) Associated Targets(non-human) Mechanisms of Action Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References
Names and Identifiers IUPAC Name (1R,4S,5R,8S,9R,10S,12R,13R)-10-ethoxy-1,5,9-trimethyl-11,14,15,16-tetraoxatetracyclo[10.3.1.04,13.08,13]hexadecane INCHI InChI=1S/C17H28O5/c1-5-18-14-11(3)13-7-6-10(2)12-8-9-16(4)20-15(19-14)17(12,13)22-21-16/h10-15H,5-9H2,1-4H3/t10-,11-,12+,13+,14+,15-,16-,17-/m1/s1 InChi Key NLYNIRQVMRLPIQ-XQLAAWPRSA-N Canonical SMILES CCOC1C(C2CCC(C3C24C(O1)OC(CC3)(OO4)C)C)C Isomeric SMILES CCO[C@@H]1[C@@H]([C@@H]2CC[C@H]([C@H]3[C@]24[C@H](O1)O[C@@](CC3)(OO4)C)C)C PubChem CID 3000469 Molecular Weight 312.40
Chemical and Physical Properties Specific Rotation[α] [α]/D +148 to +165°, c = 1 in chloroform-d Flash Point(°C) 146℃ Boil Point(°C) 372.4℃ at 760 mmHg Melt Point(°C) 80-82°C
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