Determine the necessary mass, volume, or concentration for preparing a solution.
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SKU | Size | Availability | Price | Qty |
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A107446-20mg | 20mg | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $76.90 |
Antimalarial agent
Synonyms | Artemether | 71963-77-4 | beta-Artemether | Dihydroartemisinin methyl ether | Artemetherum | Artemisininelactol methyl ether | Methyl-dihydroartemisinine | Artemetero | Paluther | beta-Dihydroartemisinin methyl ether | SM 224 | Artemetheri | Dihydroqinghaosu methyl ether | Artesap |
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Specifications & Purity | Moligand™, analytical standard, ≥98% |
Biochemical and Physiological Mechanisms | Antimalarial agent. Artemesinin derivative. Interacts with ferriprotoporphyrin IX to produce radical species. Shows analgesic and antipyretic effects in vivo. Orally active. |
Shipped In | Normal |
Grade | analytical standard, Moligand™ |
Note | Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details. |
ALogP | 3.1 |
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IUPAC Name | (1R,4S,5R,8S,9R,10S,12R,13R)-10-methoxy-1,5,9-trimethyl-11,14,15,16-tetraoxatetracyclo[10.3.1.04,13.08,13]hexadecane |
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INCHI | InChI=1S/C16H26O5/c1-9-5-6-12-10(2)13(17-4)18-14-16(12)11(9)7-8-15(3,19-14)20-21-16/h9-14H,5-8H2,1-4H3/t9-,10-,11+,12+,13+,14-,15-,16-/m1/s1 |
InChi Key | SXYIRMFQILZOAM-HVNFFKDJSA-N |
Canonical SMILES | CC1CCC2C(C(OC3C24C1CCC(O3)(OO4)C)OC)C |
Isomeric SMILES | C[C@@H]1CC[C@H]2[C@H]([C@H](O[C@H]3[C@@]24[C@H]1CC[C@](O3)(OO4)C)OC)C |
PubChem CID | 68911 |
UN Number | 3106 |
Molecular Weight | 298.38 |
CAS Registry No. | 71963-77-4 |
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PubChem CID | 68911 |
DrugBank Ligand | DB06697 |
Wikipedia | Artemether |
ChEMBL Ligand | CHEMBL566534 |
ChEBI | CHEBI:195280 |
RCSB PDB Ligand | D8Z |
DrugCentral Ligand | 245 |
Enter Lot Number to search for COA:
Specific Rotation[α] | 170° (C=1,EtOH) |
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Melt Point(°C) | 86-88°C |
Pictogram(s) | GHS07 |
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Signal | Warning |
Hazard Statements | H302:Harmful if swallowed |
Precautionary Statements | P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P270:Do not eat, drink or smoke when using this product. P330:Rinse mouth. P301+P317:IF SWALLOWED: Get medical help. |
Class | 5.2 |
Merck Index | 815 |
1. Jingjing Zhen, Faguang Ma, Rongxin Lin, Ming Yan, Yilin Wu. (2024) Porous MOFs-based self-assembled membrane with specific rebinding nanocages for selective recognition and separation at molecular level. DESALINATION, 572 (117124). [PMID:2501086] |
2. Weibai Bian, Ruixuan Zhang, Xiaohui Chen, Chuanxun Zhang, Minjia Meng. (2023) Three-Dimensional Porous PVDF Foam Imprinted Membranes with High Flux and Selectivity toward Artemisinin/Artemether. MOLECULES, 28 (21): (7452). [PMID:37959871] |
3. Jing Yan, Faguang Ma, Yilin Wu. (2023) Permselective and transparent wooden membrane with artemisinin-imprinted nanocages based on a MOFs@C3N4 self-assembly design. Materials Today Nano, 23 (100369). [PMID:] |
4. Minjia Meng, Yi Li, Hui Peng, Binrong Li, Chuanxun Zhang, Jiajia Ren, Qingluola Ren, Yan Liu, Jianming Pan. (2023) Hydrophilic imprinted MnO2 nanowires “coating” membrane with ultrahigh adsorption capacity for highly selective separation of Artemisinin/Artemether. CHEMICAL ENGINEERING JOURNAL, 466 (143020). [PMID:] |
5. Qiong Xu, Yin-Yan Duan, Ming Pan, Qi-Wang Jin, Jian-Ping Tao, Si-Yang Huang. (2023) In Vitro Evaluation Reveals Effect and Mechanism of Artemether against Toxoplasma gondii. Metabolites, 13 (4): (476). [PMID:37110135] |
6. Jing Yan, Kaicheng Zhang, Faguang Ma, Hang Cui, Yilin Wu. (2023) Scalable basswood-based PDA/GO-embedded self-assembly membrane within multilayered artemisinin-imprinted nanocage for high-selectivity cascading adsorption and transport. CHEMICAL ENGINEERING JOURNAL, 462 (142277). [PMID:] |
7. Fang Lu, Fa Zhang, Jingqi Qian, Tingting Huang, Liping Chen, Yilin Huang, Baomin Wang, Liwang Cui, Suqin Guo. (2022) Preparation and application of a specific single-chain variable fragment against artemether. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 220 (115020). [PMID:36049377] |
8. Jianxin Jia, Qi Kang, Shunzhi Liu, Yabin Song, Florence Susan Wong, Yingkun Qiu, Mingyu Li. (2022) Artemether and aspterric acid induce pancreatic alpha cells to transdifferentiate into beta cells in zebrafish. BRITISH JOURNAL OF PHARMACOLOGY, 179 (9): (1962-1977). [PMID:34871457] |
1. Shmuklarsky MJ, Klayman DL, Milhous WK, Kyle DE, Rossan RN, Ager Jr AL, Tang DB, Heiffer MH, Canfield CJ, Schuster BG. (1993) Comparison of beta-artemether and beta-arteether against malaria parasites in vitro and in vivo.. Am J Trop Med Hyg, 48 (3): (377-84). [PMID:8470775] |
2. Chan CL, Jones RL, Lau HY. (2015) All chapters. Guidelines for the Treatment of Malaria, 129 (3): (589-97). [PMID:26020088] |
3. Jingjing Zhen, Faguang Ma, Rongxin Lin, Ming Yan, Yilin Wu. (2024) Porous MOFs-based self-assembled membrane with specific rebinding nanocages for selective recognition and separation at molecular level. DESALINATION, 572 (117124). [PMID:2501086] |
4. Weibai Bian, Ruixuan Zhang, Xiaohui Chen, Chuanxun Zhang, Minjia Meng. (2023) Three-Dimensional Porous PVDF Foam Imprinted Membranes with High Flux and Selectivity toward Artemisinin/Artemether. MOLECULES, 28 (21): (7452). [PMID:37959871] |
5. Jing Yan, Faguang Ma, Yilin Wu. (2023) Permselective and transparent wooden membrane with artemisinin-imprinted nanocages based on a MOFs@C3N4 self-assembly design. Materials Today Nano, 23 (100369). [PMID:] |
6. Minjia Meng, Yi Li, Hui Peng, Binrong Li, Chuanxun Zhang, Jiajia Ren, Qingluola Ren, Yan Liu, Jianming Pan. (2023) Hydrophilic imprinted MnO2 nanowires “coating” membrane with ultrahigh adsorption capacity for highly selective separation of Artemisinin/Artemether. CHEMICAL ENGINEERING JOURNAL, 466 (143020). [PMID:] |
7. Qiong Xu, Yin-Yan Duan, Ming Pan, Qi-Wang Jin, Jian-Ping Tao, Si-Yang Huang. (2023) In Vitro Evaluation Reveals Effect and Mechanism of Artemether against Toxoplasma gondii. Metabolites, 13 (4): (476). [PMID:37110135] |
8. Jing Yan, Kaicheng Zhang, Faguang Ma, Hang Cui, Yilin Wu. (2023) Scalable basswood-based PDA/GO-embedded self-assembly membrane within multilayered artemisinin-imprinted nanocage for high-selectivity cascading adsorption and transport. CHEMICAL ENGINEERING JOURNAL, 462 (142277). [PMID:] |
9. Fang Lu, Fa Zhang, Jingqi Qian, Tingting Huang, Liping Chen, Yilin Huang, Baomin Wang, Liwang Cui, Suqin Guo. (2022) Preparation and application of a specific single-chain variable fragment against artemether. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 220 (115020). [PMID:36049377] |
10. Jianxin Jia, Qi Kang, Shunzhi Liu, Yabin Song, Florence Susan Wong, Yingkun Qiu, Mingyu Li. (2022) Artemether and aspterric acid induce pancreatic alpha cells to transdifferentiate into beta cells in zebrafish. BRITISH JOURNAL OF PHARMACOLOGY, 179 (9): (1962-1977). [PMID:34871457] |