AS 1269574 - ≥98%(HPLC), high purity , CAS No.330981-72-1, Agonist of GPR119

Item Number
A288879
Grouped product items
SKUSizeAvailabilityPrice Qty
A288879-5mg
5mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$81.90
A288879-10mg
10mg
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Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$140.90
A288879-25mg
25mg
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Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$271.90
A288879-50mg
50mg
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Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$434.90
A288879-100mg
100mg
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$652.90
A288879-250mg
250mg
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$1,469.90
A288879-1g
1g
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Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$5,289.90

GPR119 receptor agonist

Basic Description

SynonymsHY-107535 | 2-(2-(4-bromophenyl)-6-methylpyrimidin-4-ylamino)ethanol | DTXSID90416373 | 2-[[2-(4-Bromophenyl)-6-methyl-4-pyrinidinyl]amino]ethanol | 2-[[2-(4-bromophenyl)-6-methylpyrimidin-4-yl]amino]ethanol | AKOS005229115 | Z1095349900 | CS-0028832 | Q2
Specifications & PurityMoligand™, ≥98%(HPLC)
Biochemical and Physiological MechanismsGPR119 receptor agonist (EC50= 2.5μM in HEK293 cells expressing human GPR119). Enhances insulin secretion stimulated by glucosein vivo. Stimulates proGlukagon gene promoter actvity. Orally available.
Storage TempProtected from light,Store at -20°C
Shipped InIce chest + Ice pads
GradeMoligand™
Action TypeAGONIST
Mechanism of actionAgonist of GPR119

Associated Targets(Human)

CYP1A2 Tchem Cytochrome P450 1A2 (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
GPR119 Tclin Glucose-dependent insulinotropic receptor (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
CYP1A2 Tchem Cytochrome P450 1A2 (26471 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

Hdac6 Histone deacetylase 6 (222 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mus musculus (284745 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
rep Replicase polyprotein 1ab (378 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Gpr119 Glucose-dependent insulinotropic receptor (270 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

IUPAC Name 2-[[2-(4-bromophenyl)-6-methylpyrimidin-4-yl]amino]ethanol
INCHI InChI=1S/C13H14BrN3O/c1-9-8-12(15-6-7-18)17-13(16-9)10-2-4-11(14)5-3-10/h2-5,8,18H,6-7H2,1H3,(H,15,16,17)
InChi Key DUKPGOOUJNUIOI-UHFFFAOYSA-N
Canonical SMILES CC1=CC(=NC(=N1)C2=CC=C(C=C2)Br)NCCO
Isomeric SMILES CC1=CC(=NC(=N1)C2=CC=C(C=C2)Br)NCCO
PubChem CID 5332859
Molecular Weight 308.17

Certificates

Certificate of Analysis(COA)

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7 results found

Lot NumberCertificate TypeDateItem
D2230104Certificate of AnalysisMar 07, 2022 A288879
D2230116Certificate of AnalysisMar 07, 2022 A288879
D2230124Certificate of AnalysisMar 07, 2022 A288879
D2230129Certificate of AnalysisMar 07, 2022 A288879
D2230134Certificate of AnalysisMar 07, 2022 A288879
D2230136Certificate of AnalysisMar 07, 2022 A288879
D2230139Certificate of AnalysisMar 07, 2022 A288879

Chemical and Physical Properties

SolubilitySolvent:DMSO, Max Conc. mg/mL: 30.82, Max Conc. mM: 100; Solvent:ethanol, Max Conc. mg/mL: 30.82, Max Conc. mM: 100
Sensitivitylight sensitive

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Solution Calculators