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AS 8351 - ≥98%(HPLC), high purity , CAS No.796-42-9
Induces reprogramming of fibroblasts into functional cardiomyocytes
Basic Description Synonyms AS-8351 | NSC-51355 Specifications & Purity ≥98%(HPLC) Biochemical and Physiological Mechanisms Induces reprogramming of human fetal lung fibroblasts into functional cardiomyocytes, in combination withCHIR 99021,A83-01,BIX 01294, SC1,Y-27632, OAC2,SU 16fand JNJ 10198409. Iron chelator and putative inhibitor of KDM5B. Storage Temp Store at -20°C Shipped In Ice chest + Ice pads
Associated Targets(Human) Associated Targets(non-human) Mechanisms of Action Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References
Names and Identifiers IUPAC Name N-[(2-hydroxynaphthalen-1-yl)methylideneamino]pyridine-4-carboxamide INCHI InChI=1S/C17H13N3O2/c21-16-6-5-12-3-1-2-4-14(12)15(16)11-19-20-17(22)13-7-9-18-10-8-13/h1-11,21H,(H,20,22) InChi Key WQSHHAVECQJKLX-UHFFFAOYSA-N Canonical SMILES C1=CC=C2C(=C1)C=CC(=C2C=NNC(=O)C3=CC=NC=C3)O Isomeric SMILES C1=CC=C2C(=C1)C=CC(=C2C=NNC(=O)C3=CC=NC=C3)O PubChem CID 4491 Molecular Weight 291.3
Chemical and Physical Properties Solubility Solvent:DMSO, Max Conc. mg/mL: 29.13, Max Conc. mM: 100 Sensitivity Hygroscopic,Heat Sensitive Melt Point(°C) 266 °C
Safety and Hazards(GHS) Pictogram(s) GHS07 Signal Warning Hazard Statements H315: Causes skin irritation
H319: Causes serious eye irritation
H335: May cause respiratory irritation
Precautionary Statements P261: Avoid breathing dust/fume/gas/mist/vapors/spray.
P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.
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I2221057