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Aspartame - 98%, high purity , CAS No.22839-47-0

8 Citations

≥98%

CAS#: 22839-47-0
Formula: C₁₄H₁₈N₂O₅
Molecular Weight: 294.3
Beilstein Registry Number: 2223850
EC Number: 245-261-3
MDL number: MFCD00002724
PubChem CID: 134601
PubChem SID: 488187825

Item Number

A113247

Grouped product items
SKU	Size	Availability	Price
A113247-5g	5g	In stock	$9.90
A113247-25g	25g	In stock	$27.90
A113247-100g	100g	In stock	$65.90
A113247-500g	500g	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$261.90

Methyl ester of aspartic acid/phenylalanine dipeptide

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polypeptide

Basic Description

Synonyms	N-L-α-Aspartyl-L-phenylalanine 1-Methyl Ester \| H-Asp-Phe-OMe
Specifications & Purity	≥98%
Biochemical and Physiological Mechanisms	Asp-Phe methyl ester (Asp-Phe-OMe) is used as a synthetic sweeter, sugar substitute. Asp-Phe methyl ester is being studied for a variety of potential benefits as a nutrition supplement, such as the delay of osteoarthritis and modulation of rheumatoid fact
Storage Temp	Store at 2-8°C
Shipped In	Wet ice
Note	Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description	Asp-Phe methyl ester is used for the preparation of Ad libitum Standard Chow, with ad libitum drinking water (animals control diet) containing Asp-Phe methyl ester. It is also used for the TFA diet preparation (TFA diet with ad lib drinking water contains Asp-Phe methyl ester

Product Properties

ALogP	-2.7

Associated Targets(Human)

TSHR Tclin Thyroid stimulating hormone receptor (29986 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

PPARG Tclin Peroxisome proliferator-activated receptor gamma (15191 Activities)

Discover Target: PPARG

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Homo sapiens (32628 Activities)

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SETD7 Tchem Histone-lysine N-methyltransferase SETD7 (390 Activities)

Discover Target: SETD7

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

KDM4A Tchem Lysine-specific demethylase 4A (52245 Activities)

Discover Target: KDM4A

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ABCB11 Tchem Bile salt export pump (2311 Activities)

Discover Target: ABCB11

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

GMNN Tbio Geminin (128009 Activities)

Discover Target: GMNN

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

TAS1R2 Tbio Taste receptor type 1 member 2 (15 Activities)

Discover Target: TAS1R2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

TAS1R3 Tbio Taste receptor type 1 member 3 (10 Activities)

Discover Target: TAS1R3

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SLC22A8 Tclin Solute carrier family 22 member 8 (241 Activities)

Discover Target: SLC22A8

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SLCO1B1 Tchem Solute carrier organic anion transporter family member 1B1 (2672 Activities)

Discover Target: SLCO1B1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SLCO1B3 Tchem Solute carrier organic anion transporter family member 1B3 (2517 Activities)

Discover Target: SLCO1B3

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

TAS2R31 Tchem Taste receptor type 2 member 31 (86 Activities)

Discover Target: TAS2R31

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SLC22A11 Tclin Solute carrier family 22 member 11 (82 Activities)

Discover Target: SLC22A11

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

TAS1R3 Tbio T1R1/T1R3 (473 Activities)

Discover Target: TAS1R3

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Associated Targets(non-human)

Hdac6 Histone deacetylase 6 (222 Activities)

Discover Target: Hdac6

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Plasmodium falciparum (966862 Activities)

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rep Replicase polyprotein 1ab (378 Activities)

Discover Target: rep

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Slc22a6 Solute carrier family 22 member 6 (141 Activities)

Discover Target: Slc22a6

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mechanisms of Action

Mechanism of Action	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	References

Names and Identifiers

Pubchem Sid	488187825
Pubchem Sid Url	https://pubchem.ncbi.nlm.nih.gov/substance/488187825
IUPAC Name	(3S)-3-amino-4-[[(2S)-1-methoxy-1-oxo-3-phenylpropan-2-yl]amino]-4-oxobutanoic acid
INCHI	InChI=1S/C14H18N2O5/c1-21-14(20)11(7-9-5-3-2-4-6-9)16-13(19)10(15)8-12(17)18/h2-6,10-11H,7-8,15H2,1H3,(H,16,19)(H,17,18)/t10-,11-/m0/s1
InChi Key	IAOZJIPTCAWIRG-QWRGUYRKSA-N
Canonical SMILES	COC(=O)C(CC1=CC=CC=C1)NC(=O)C(CC(=O)O)N
Isomeric SMILES	COC(=O)[C@H](CC1=CC=CC=C1)NC(=O)[C@H](CC(=O)O)N
WGK Germany	2
RTECS	WM3407000
PubChem CID	134601
Molecular Weight	294.3
Beilstein	2223850
Reaxy-Rn	2223850

Certificates

Certificate of Analysis(COA)

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24 results found

Lot Number	Certificate Type	Date	Item
H2407092	Certificate of Analysis	Jul 08, 2024	A113247
H2407091	Certificate of Analysis	Jul 08, 2024	A113247
D2416218	Certificate of Analysis	Mar 14, 2024	A113247
D2416217	Certificate of Analysis	Mar 14, 2024	A113247
D2416206	Certificate of Analysis	Mar 14, 2024	A113247
D2416210	Certificate of Analysis	Mar 14, 2024	A113247
D2416205	Certificate of Analysis	Mar 14, 2024	A113247
D2411120	Certificate of Analysis	Mar 13, 2024	A113247
D2411121	Certificate of Analysis	Mar 13, 2024	A113247
D2411122	Certificate of Analysis	Mar 13, 2024	A113247
D2411123	Certificate of Analysis	Mar 13, 2024	A113247
L2314022	Certificate of Analysis	Dec 12, 2022	A113247
B2302659	Certificate of Analysis	Dec 12, 2022	A113247
B2302667	Certificate of Analysis	Dec 12, 2022	A113247
B2302666	Certificate of Analysis	Dec 12, 2022	A113247
B2302665	Certificate of Analysis	Dec 12, 2022	A113247
B2302664	Certificate of Analysis	Dec 12, 2022	A113247
B2302663	Certificate of Analysis	Dec 12, 2022	A113247
B2302662	Certificate of Analysis	Dec 12, 2022	A113247
K2203180	Certificate of Analysis	Dec 04, 2021	A113247
F2101064	Certificate of Analysis	Jun 08, 2021	A113247
F2101065	Certificate of Analysis	Jun 08, 2021	A113247
F2101102	Certificate of Analysis	Jun 08, 2021	A113247
H2223017	Certificate of Analysis	Jun 08, 2021	A113247

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Chemical and Physical Properties

Solubility	Soluble in formic acid, dimethyl sulfoxide. Sparingly soluble in water and ethanol.
Specific Rotation[α]	14.5 ° (C=4, 15mol/L Formic Acid)
Melt Point(°C)	248-250°C

Safety and Hazards(GHS)

WGK Germany	2
RTECS	WM3407000
Reaxy-Rn	2223850
Merck Index	839

Alternative Products

Citations of This Product

How to Cite Aladdin Scientific Products?

1. Zhijian Ke, Junyun Song, Jingrui Ma, Mengting Wang, Haiguang Mao, Chunli Xia, Lili Qi, Yidong Zhou, Jinbo Wang. (2024) Isolation and characterization of the aspartame-degrading strain Pseudarthrobacter sp. AS-1. ENVIRONMENTAL POLLUTION, 340 (19): (122883). [PMID:37944888] [10.1016/j.envpol.2023.122883]
2. Linyang Song, Xiaoyi He, Mengxia Wang, Lixia Li, Jing Liu, Guoying Li, Junhua Yang. (2023) IFN-γ mediated neuroinflammation and behaviour abnormality after maternal exposure to low dose mixture of food additives and pesticides. FOOD AND AGRICULTURAL IMMUNOLOGY, 34 (1): (2226841). [PMID:] [10.1080/09540105.2023.2226841]
3. Jun Dong, Haoran Wu, Yi Cao, Jiaxin Yuan, Qingyan Han, Wei Gao, Chengyun Zhang, Jianxia Qi, Mengtao Sun. (2023) Capillary-force-assisted self-assembly of gold nanoparticles into highly ordered plasmonic thin films for ultrasensitive SERS. PHYSICAL CHEMISTRY CHEMICAL PHYSICS, 25 (3): (1649-1658). [PMID:36541051] [10.1039/D2CP05158C]
4. Qichao Ye, Chen Men, Lili Tian, Yuxin Liu, Lei Zhan, Yuan Fang Li, Cheng Zhi Huang, Shu Jun Zhen. (2021) Preparation of a molecularly imprinted test strip for point-of-care detection of thiodiglycol, a sulfur mustard poisoning metabolic marker. TALANTA, 234 (122701). [PMID:34364498] [10.1016/j.talanta.2021.122701]
5. Ferry Saputra, Yu-Heng Lai, Rey Arturo T. Fernandez, Allan Patrick G. Macabeo, Hong-Thih Lai, Jong-Chin Huang, Chung-Der Hsiao. (2021) Acute and Sub-Chronic Exposure to Artificial Sweeteners at the Highest Environmentally Relevant Concentration Induce Less Cardiovascular Physiology Alterations in Zebrafish Larvae. Biology-Basel, 10 (6): (548). [PMID:34207293] [10.3390/biology10060548]
6. Sun Xiao-Dong, Wu Hai-Long, Liu Zhi, Chen Yue, Liu Qian, Ding Yu-Jie, Yu Ru-Qin. (2019) Rapid and Sensitive Detection of Multi-Class Food Additives in Beverages for Quality Control by Using HPLC-DAD and Chemometrics Methods. Food Analytical Methods, 12 (2): (381-393). [PMID:] [10.1007/s12161-018-1370-3]
7. Hongmei Zhang, Shixin Sun, Yanqing Wang, Zhenghao Fei, Jian Cao. (2018) Binding mechanism of five typical sweeteners with bovine serum albumin. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, 205 (40). [PMID:30015031] [10.1016/j.saa.2018.07.013]
8. Li’na Qiao, Sihua Qian, Yuhui Wang, Hengwei Lin. (2018) A colorimetric sensor array based on sulfuric acid assisted KMnO4 fading for the detection and identification of pesticides. TALANTA, 181 (305). [PMID:29426516] [10.1016/j.talanta.2018.01.029]

References

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