Determine the necessary mass, volume, or concentration for preparing a solution.
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SKU | Size | Availability | Price | Qty |
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A423026-1ml | 1ml | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $69.90 |
β 1 Adrenoceptor antagonist
Synonyms | atenolol | 29122-68-7 | Tenormin | Prenormine | Blokium | Myocord | Normiten | (RS)-Atenolol | Duraatenolol | Betacard | Corotenol | Tenormine | Atehexal | Betablok | Cuxanorm | Juvental | Selobloc | Tenoblock | Antipressan | Atenblock | Farnormin | Internolol | Premorine | Vericordin | Anselol | Atcardi |
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Specifications & Purity | Moligand™, 10mM in DMSO |
Biochemical and Physiological Mechanisms | Selective β1-adrenoceptor antagonist; antihypertensive; antianginal; antiarrhythmic.β 1 Adrenoceptor antagonist. K i values are 1.14 and 48.7 μM for receptor subtypes β 1 and β 2 , respectively. Antihypertensive. Limited ability to cross the blood-brain b |
Storage Temp | Store at -80°C |
Shipped In | Ice chest + Ice pads |
Grade | Moligand™ |
Product Description | (RS)-Atenolol is a cardioselective β-adrenergic blocker. It is considered to be antihypertensive, antianginal, and antiarrhythmic. (RS)-Atenolol is an inhibitor of β1-AR and β2-AR. |
ALogP | 0.2 |
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IUPAC Name | 2-[4-[2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl]acetamide |
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INCHI | InChI=1S/C14H22N2O3/c1-10(2)16-8-12(17)9-19-13-5-3-11(4-6-13)7-14(15)18/h3-6,10,12,16-17H,7-9H2,1-2H3,(H2,15,18) |
InChi Key | METKIMKYRPQLGS-UHFFFAOYSA-N |
Canonical SMILES | CC(C)NCC(COC1=CC=C(C=C1)CC(=O)N)O |
Isomeric SMILES | CC(C)NCC(COC1=CC=C(C=C1)CC(=O)N)O |
WGK Germany | 2 |
RTECS | AC3600000 |
PubChem CID | 2249 |
Molecular Weight | 266.34 |
Enter Lot Number to search for COA:
Melt Point(°C) | 151-155℃ |
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Pictogram(s) | GHS08, GHS07 |
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Signal | Warning |
Hazard Statements | H319:Causes serious eye irritation H351:Suspected of causing cancer H302:Harmful if swallowed H362:May cause harm to breast-fed children |
Precautionary Statements | P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P260:Do not breathe dust/fume/gas/mist/vapors/spray. P270:Do not eat, drink or smoke when using this product. P330:Rinse mouth. P263:Avoid contact during pregnancy/while nursing. P203:Obtain, read and follow all safety instructions before use. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P301+P317:IF SWALLOWED: Get medical help. P318:if exposed or concerned, get medical advice. P337+P317:If eye irritation persists: Get medical help. |
WGK Germany | 2 |
RTECS | AC3600000 |
1. Juan Luo, Bowen Zhou, Chenjun Dong, Rongrong He, Yuling Zhang, Tao He. (2024) Effect of substrate morphology on characteristics of layer-by-layer self-assembly nanofiltration membrane for micropollutants removal. DESALINATION, 574 (117229). [PMID:] |
2. Lianxu Wang, Zhen Lei, Sining Yun, Xiaohuan Yang, Rong Chen. (2024) Quantitative structure-biotransformation relationships of organic micropollutants in aerobic and anaerobic wastewater treatments. SCIENCE OF THE TOTAL ENVIRONMENT, 912 (169170). [PMID:38072270] |
3. Xiancheng Wan, Huili Wang, Qiuhui Qian, Jin Yan. (2023) MiR-133b as a crucial regulator of TCS-induced cardiotoxicity via activating β-adrenergic receptor signaling pathway in zebrafish embryos. ENVIRONMENTAL POLLUTION, 334 (122199). [PMID:37467918] |
4. Jun Young Kim, Kang Hoon Lee, Jae Won Lee, Imtiaz Afzal Khan, Jong-Oh Kim. (2023) Structural and performance variation of PES/PVDF membranes after exposure to the pretreated feed water of CECs. CHEMOSPHERE, 335 (139096). [PMID:37295688] |
5. Yinqiao Zhang, Yang Guo, Jingyun Fang, Kaiheng Guo, Gang Yu, Yujue Wang. (2023) Characterization of UV/chlorine process for micropollutant abatement by probe compound-based kinetic models. WATER RESEARCH, 237 (119985). [PMID:37098285] |
6. Qian Wang, Can He, Yue Shan, Zhongguo Zhang, Jiuyi Li. (2023) Catalytic ozonation of atenolol by Mn-Ce@Al2O3 catalysts: Efficiency, mechanism and degradation pathways. Journal of Environmental Chemical Engineering, 11 (109444). [PMID:] |
7. Li Chen, Tahir Maqbool, Ghazanfar Nazir, Congyu Hou, Yanna Xu, Yulong Yang, Xihui Zhang. (2023) Peroxymonosulfate activated by composite ceramic membrane for the removal of pharmaceuticals and personal care products (PPCPs) mixture: Insights of catalytic and noncatalytic oxidation. WATER RESEARCH, 229 (119444). [PMID:36470049] |
8. Jieqing Feng, Qisheng Zhong, Ting Zhou. (2022) Online Pressure Change Focusing-Supercritical Fluid Selective Extraction Chromatography for Analyzing Chiral Drugs in Microliter-Scale Plasma Samples. ANALYTICAL CHEMISTRY, 94 (46): (16222–16230). [PMID:36356211] |
9. Wenqi Diao, Jin Yan, Xuedong Wang, Qiuhui Qian, Huili Wang. (2023) Mechanisms regarding cardiac toxicity triggered by up-regulation of miR-144 in larval zebrafish upon exposure to triclosan. JOURNAL OF HAZARDOUS MATERIALS, 443 (130297). [PMID:36368065] |
10. Yafang Zhang, Shuning Yang, Linsheng Wei, Xiaoyang Zhao, Xiangdong Lu. (2022) Degradation characteristics of p-nitrophenol and atenolol by carbon nitride modified by graphene quantum dots. ENVIRONMENTAL TECHNOLOGY, [PMID:36205067] |
11. Kun Chen, Shengqiu Liu, Wei Zhu, Panchao Yin. (2022) Surface Engineering Promoted Insulin-Sensitizing Activities of Sub-Nanoscale Vanadate Clusters through Regulated Pharmacokinetics and Bioavailability. Small, 18 (40): (2203957). [PMID:36058647] |
12. Jian Zhao, Shangbiao Fang, Weixiao Qi, Huijuan Liu, Jiuhui Qu. (2022) Do NH4+-N and AOB affect atenolol removal during simulated riverbank filtration?. CHEMOSPHERE, 301 (134653). [PMID:35447203] |
13. Long Jiang, Tao Jing, Xiantao Shen. (2022) Molecularly imprinted wax. Journal of Materials Chemistry B, 10 (35): (6742-6751). [PMID:35377383] |
14. Di Liu, Yunning Chen, Renquan Guan, Jie Zhao, Huimin Jin, Siyi Zhang, Qingkun Shang. (2022) Photocatalytic performance of heterojunction S-Tyr-NDI-Tyr/TiO2 formed by self-assembled naphthalimide derivatives and titanium dioxide. CHEMOSPHERE, 296 (134046). [PMID:35183575] |
1. Juan Luo, Bowen Zhou, Chenjun Dong, Rongrong He, Yuling Zhang, Tao He. (2024) Effect of substrate morphology on characteristics of layer-by-layer self-assembly nanofiltration membrane for micropollutants removal. DESALINATION, 574 (117229). [PMID:] |
2. Lianxu Wang, Zhen Lei, Sining Yun, Xiaohuan Yang, Rong Chen. (2024) Quantitative structure-biotransformation relationships of organic micropollutants in aerobic and anaerobic wastewater treatments. SCIENCE OF THE TOTAL ENVIRONMENT, 912 (169170). [PMID:38072270] |
3. Xiancheng Wan, Huili Wang, Qiuhui Qian, Jin Yan. (2023) MiR-133b as a crucial regulator of TCS-induced cardiotoxicity via activating β-adrenergic receptor signaling pathway in zebrafish embryos. ENVIRONMENTAL POLLUTION, 334 (122199). [PMID:37467918] |
4. Jun Young Kim, Kang Hoon Lee, Jae Won Lee, Imtiaz Afzal Khan, Jong-Oh Kim. (2023) Structural and performance variation of PES/PVDF membranes after exposure to the pretreated feed water of CECs. CHEMOSPHERE, 335 (139096). [PMID:37295688] |
5. Yinqiao Zhang, Yang Guo, Jingyun Fang, Kaiheng Guo, Gang Yu, Yujue Wang. (2023) Characterization of UV/chlorine process for micropollutant abatement by probe compound-based kinetic models. WATER RESEARCH, 237 (119985). [PMID:37098285] |
6. Qian Wang, Can He, Yue Shan, Zhongguo Zhang, Jiuyi Li. (2023) Catalytic ozonation of atenolol by Mn-Ce@Al2O3 catalysts: Efficiency, mechanism and degradation pathways. Journal of Environmental Chemical Engineering, 11 (109444). [PMID:] |
7. Li Chen, Tahir Maqbool, Ghazanfar Nazir, Congyu Hou, Yanna Xu, Yulong Yang, Xihui Zhang. (2023) Peroxymonosulfate activated by composite ceramic membrane for the removal of pharmaceuticals and personal care products (PPCPs) mixture: Insights of catalytic and noncatalytic oxidation. WATER RESEARCH, 229 (119444). [PMID:36470049] |
8. Jieqing Feng, Qisheng Zhong, Ting Zhou. (2022) Online Pressure Change Focusing-Supercritical Fluid Selective Extraction Chromatography for Analyzing Chiral Drugs in Microliter-Scale Plasma Samples. ANALYTICAL CHEMISTRY, 94 (46): (16222–16230). [PMID:36356211] |
9. Wenqi Diao, Jin Yan, Xuedong Wang, Qiuhui Qian, Huili Wang. (2023) Mechanisms regarding cardiac toxicity triggered by up-regulation of miR-144 in larval zebrafish upon exposure to triclosan. JOURNAL OF HAZARDOUS MATERIALS, 443 (130297). [PMID:36368065] |
10. Yafang Zhang, Shuning Yang, Linsheng Wei, Xiaoyang Zhao, Xiangdong Lu. (2022) Degradation characteristics of p-nitrophenol and atenolol by carbon nitride modified by graphene quantum dots. ENVIRONMENTAL TECHNOLOGY, [PMID:36205067] |
11. Kun Chen, Shengqiu Liu, Wei Zhu, Panchao Yin. (2022) Surface Engineering Promoted Insulin-Sensitizing Activities of Sub-Nanoscale Vanadate Clusters through Regulated Pharmacokinetics and Bioavailability. Small, 18 (40): (2203957). [PMID:36058647] |
12. Jian Zhao, Shangbiao Fang, Weixiao Qi, Huijuan Liu, Jiuhui Qu. (2022) Do NH4+-N and AOB affect atenolol removal during simulated riverbank filtration?. CHEMOSPHERE, 301 (134653). [PMID:35447203] |
13. Long Jiang, Tao Jing, Xiantao Shen. (2022) Molecularly imprinted wax. Journal of Materials Chemistry B, 10 (35): (6742-6751). [PMID:35377383] |
14. Di Liu, Yunning Chen, Renquan Guan, Jie Zhao, Huimin Jin, Siyi Zhang, Qingkun Shang. (2022) Photocatalytic performance of heterojunction S-Tyr-NDI-Tyr/TiO2 formed by self-assembled naphthalimide derivatives and titanium dioxide. CHEMOSPHERE, 296 (134046). [PMID:35183575] |