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Atipamezole - ≥98% (HPLC), high purity , CAS No.104054-27-5, Antagonist of α 2A-adrenoceptor;Antagonist of α 2B-adrenoceptor;Antagonist of α 2C-adrenoceptor

1 Citations

Moligand™

≥98%(HPLC)

CAS#: 104054-27-5
Formula: C₁₄H₁₆N₂
Molecular Weight: 212.29
MDL number: MFCD00864502
PubChem CID: 71310
PubChem SID: 488184646

Item Number

A132977

Grouped product items
SKU	Size	Availability	Price
A132977-5mg	5mg	In stock	$34.90
A132977-25mg	25mg	In stock	$123.90
A132977-100mg	100mg	In stock	$343.90
A132977-250mg	250mg	In stock	$686.90
A132977-1g	1g	In stock	$1,716.90

View related series

α2A-adrenoceptor Antagonist α2B-adrenoceptor Antagonist α2C-adrenoceptor Antagonist

Basic Description

Synonyms	MPV1248 \| MPV 1248 \| PDSP2_001566 \| antipamezole \| CAS_104054-27-5 \| PDSP1_001582 \| Atipamezolum (Latin) \| Aurin No. 555 \| BDBM81807 \| AC-1614 \| DTXSID2049135 \| 4-(2-ethyl-2-indanyl)imidazole. \| NCGC00182707-02 \| NSC_71310 \| Vioxx Dolor \| D03002 \| FT-0603
Specifications & Purity	Moligand™, ≥98%(HPLC)
Storage Temp	Room temperature
Shipped In	Normal
Grade	Moligand™
Action Type	ANTAGONIST
Mechanism of action	Antagonist of α 2A-adrenoceptor;Antagonist of α 2B-adrenoceptor;Antagonist of α 2C-adrenoceptor
Product Description	Atipamezole(MPV1248) is an alpha-adrenoceptor antagonist with high affinity and selectivity for the alpha 2-receptor.

Associated Targets(Human)

ADRA2B Tclin Alpha-2B adrenergic receptor (1 Activities)

Discover Target: ADRA2B

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

ADRA2C Tclin Alpha-2C adrenergic receptor (1 Activities)

Discover Target: ADRA2C

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

ADRA2A Tclin Alpha-2A adrenergic receptor (3 Activities)

Discover Target: ADRA2A

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

ADRA2A Tclin Alpha-2a adrenergic receptor (9450 Activities)

Discover Target: ADRA2A

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SLC6A2 Tclin Norepinephrine transporter (10102 Activities)

Discover Target: SLC6A2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SLC6A4 Tclin Serotonin transporter (12625 Activities)

Discover Target: SLC6A4

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ADRA1B Tclin Alpha-1b adrenergic receptor (2912 Activities)

Discover Target: ADRA1B

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ADRA2B Tclin Alpha-2b adrenergic receptor (4412 Activities)

Discover Target: ADRA2B

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ADRA2C Tclin Alpha-2c adrenergic receptor (4876 Activities)

Discover Target: ADRA2C

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 (345557 Activities)

Discover Target: TDP1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Associated Targets(non-human)

Hdac6 Histone deacetylase 6 (222 Activities)

Discover Target: Hdac6

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Galc Galactocerebrosidase (11 Activities)

Discover Target: Galc

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mus musculus (284745 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Adra1b Adrenergic receptor alpha-1 (5652 Activities)

Discover Target: Adra1b

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Adra2c Adrenergic receptor alpha-2 (3313 Activities)

Discover Target: Adra2c

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mechanisms of Action

Mechanism of Action	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	References

Names and Identifiers

Pubchem Sid	488184646
Pubchem Sid Url	https://pubchem.ncbi.nlm.nih.gov/substance/488184646
IUPAC Name	5-(2-ethyl-1,3-dihydroinden-2-yl)-1H-imidazole
INCHI	InChI=1S/C14H16N2/c1-2-14(13-9-15-10-16-13)7-11-5-3-4-6-12(11)8-14/h3-6,9-10H,2,7-8H2,1H3,(H,15,16)
InChi Key	HSWPZIDYAHLZDD-UHFFFAOYSA-N
Canonical SMILES	CCC1(CC2=CC=CC=C2C1)C3=CN=CN3
Isomeric SMILES	CCC1(CC2=CC=CC=C2C1)C3=CN=CN3
WGK Germany	3
Alternate CAS	104054-27-5
PubChem CID	71310
MeSH Entry Terms	1H-imidazole, 4-(2-ethyl-2,3-dihydro-1H-inden-2-yl)-;antipamezole;atipamezole;MPV 1248;MPV-1248
Molecular Weight	212.29

Database links

PubChem SID	488184646

Certificates

Certificate of Analysis(COA)

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Find and download the COA for your product by matching the lot number on the packaging.

9 results found

Lot Number	Certificate Type	Date	Item
J2211540	Certificate of Analysis	Jul 19, 2024	A132977
J2211552	Certificate of Analysis	Jul 19, 2024	A132977
J2211559	Certificate of Analysis	Jul 19, 2024	A132977
J2211560	Certificate of Analysis	Jul 19, 2024	A132977
J2211569	Certificate of Analysis	Jul 19, 2024	A132977
G1605067	Certificate of Analysis	Nov 20, 2023	A132977
A1824001	Certificate of Analysis	Jun 08, 2023	A132977
A1824010	Certificate of Analysis	Jun 08, 2023	A132977
E2315572	Certificate of Analysis	Aug 26, 2022	A132977

Chemical and Physical Properties

Melt Point(°C)	129 °C

Safety and Hazards(GHS)

WGK Germany	3
Merck Index	861

Alternative Products

Citations of This Product

How to Cite Aladdin Scientific Products?

1. Rongzong Qiu, Weifeng Yao, Haocong Ji, Dongdong Yuan, Xiaofeng Gao, Weiping Sha, Fei Wang, Pinjie Huang, Ziqing Hei. (2018) Dexmedetomidine restores septic renal function via promoting inflammation resolution in a rat sepsis model. LIFE SCIENCES, 204 (1). [PMID:29733849] [10.1016/j.lfs.2018.05.001]

References

1. Rongzong Qiu, Weifeng Yao, Haocong Ji, Dongdong Yuan, Xiaofeng Gao, Weiping Sha, Fei Wang, Pinjie Huang, Ziqing Hei. (2018) Dexmedetomidine restores septic renal function via promoting inflammation resolution in a rat sepsis model. LIFE SCIENCES, 204 (1). [PMID:29733849] [10.1016/j.lfs.2018.05.001]

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