Atipamezole - ≥98% (HPLC), high purity , CAS No.104054-27-5, Antagonist of α 2A-adrenoceptor;Antagonist of α 2B-adrenoceptor;Antagonist of α 2C-adrenoceptor

Item Number
A132977
Grouped product items
SKUSizeAvailabilityPrice Qty
A132977-5mg
5mg
In stock
$34.90
A132977-25mg
25mg
In stock
$123.90
A132977-100mg
100mg
In stock
$343.90
A132977-250mg
250mg
In stock
$686.90
A132977-1g
1g
In stock
$1,716.90

Basic Description

SynonymsMPV1248 | MPV 1248 | PDSP2_001566 | antipamezole | CAS_104054-27-5 | PDSP1_001582 | Atipamezolum (Latin) | Aurin No. 555 | BDBM81807 | AC-1614 | DTXSID2049135 | 4-(2-ethyl-2-indanyl)imidazole. | NCGC00182707-02 | NSC_71310 | Vioxx Dolor | D03002 | FT-0603
Specifications & PurityMoligand™, ≥98%(HPLC)
Storage TempRoom temperature
Shipped InNormal
GradeMoligand™
Action TypeANTAGONIST
Mechanism of actionAntagonist of α 2A-adrenoceptor;Antagonist of α 2B-adrenoceptor;Antagonist of α 2C-adrenoceptor
Product Description

Atipamezole(MPV1248) is an alpha-adrenoceptor antagonist with high affinity and selectivity for the alpha 2-receptor.

Associated Targets(Human)

ADRA2B Tclin Alpha-2B adrenergic receptor (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
ADRA2C Tclin Alpha-2C adrenergic receptor (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
ADRA2A Tclin Alpha-2A adrenergic receptor (3 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
ADRA2A Tclin Alpha-2a adrenergic receptor (9450 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLC6A2 Tclin Norepinephrine transporter (10102 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLC6A4 Tclin Serotonin transporter (12625 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ADRA1B Tclin Alpha-1b adrenergic receptor (2912 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ADRA2B Tclin Alpha-2b adrenergic receptor (4412 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ADRA2C Tclin Alpha-2c adrenergic receptor (4876 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 (345557 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

Hdac6 Histone deacetylase 6 (222 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Galc Galactocerebrosidase (11 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mus musculus (284745 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Adra1b Adrenergic receptor alpha-1 (5652 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Adra2c Adrenergic receptor alpha-2 (3313 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SARS-CoV-2 (38078 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Names and Identifiers

Pubchem Sid488184646
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/488184646
IUPAC Name 5-(2-ethyl-1,3-dihydroinden-2-yl)-1H-imidazole
INCHI InChI=1S/C14H16N2/c1-2-14(13-9-15-10-16-13)7-11-5-3-4-6-12(11)8-14/h3-6,9-10H,2,7-8H2,1H3,(H,15,16)
InChi Key HSWPZIDYAHLZDD-UHFFFAOYSA-N
Canonical SMILES CCC1(CC2=CC=CC=C2C1)C3=CN=CN3
Isomeric SMILES CCC1(CC2=CC=CC=C2C1)C3=CN=CN3
WGK Germany 3
Alternate CAS 104054-27-5
PubChem CID 71310
MeSH Entry Terms 1H-imidazole, 4-(2-ethyl-2,3-dihydro-1H-inden-2-yl)-;antipamezole;atipamezole;MPV 1248;MPV-1248
Molecular Weight 212.29

Certificates

Certificate of Analysis(COA)

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9 results found

Lot NumberCertificate TypeDateItem
J2211540Certificate of AnalysisJul 19, 2024 A132977
J2211552Certificate of AnalysisJul 19, 2024 A132977
J2211559Certificate of AnalysisJul 19, 2024 A132977
J2211560Certificate of AnalysisJul 19, 2024 A132977
J2211569Certificate of AnalysisJul 19, 2024 A132977
G1605067Certificate of AnalysisNov 20, 2023 A132977
A1824001Certificate of AnalysisJun 08, 2023 A132977
A1824010Certificate of AnalysisJun 08, 2023 A132977
E2315572Certificate of AnalysisAug 26, 2022 A132977

Chemical and Physical Properties

Melt Point(°C)129 °C

Safety and Hazards(GHS)

WGK Germany 3
Merck Index 861

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