Atopaxar - 98%, high purity , Proteinase-activated receptor 1 antagonist, CAS No.751475-53-3, Proteinase-activated receptor 1 antagonist

Item Number

A412332

• Synonyms: Atopaxar|751475-53-3|E5555|ER-172594-00|Atopaxar [USAN:INN]|E-5555|UNII-HTI275SD2D|HTI275SD2D|Atopaxar [USAN]|E 5555|1-(3-(tert-Butyl)-4-methoxy-5-morpholinophenyl)-2-(5,6-diethoxy-7-fluoro-1-iminoisoindolin-2-yl)ethanone|Atopaxar (USAN)|1-(3-(tert-butyl)
• Specifications & Purity: Moligand™, ≥98%
• Biochemical and Physiological Mechanisms: Atopaxar (E5555, ER-172594-00) is a potent and orally-active inhibitor of Protease-activated receptor-1 (PAR-1). E5555 inhibited the binding of a high-affinity thrombin receptor-activating peptide ([(3)H]haTRAP) to PAR-1 with IC50 of 0.019μM.
• Storage Temp: Store at -20°C
• Shipped In: Ice chest + Ice pads
• Grade: Moligand™
• Action Type: ANTAGONIST
• Mechanism of action: Proteinase-activated receptor 1 antagonist

Product Description

Atopaxar (E5555) is a potent, orally active, selective and reversible thrombin receptor protease-activated receptor-1 (PAR-1) antagonist. Atopaxar, an antiplatelet agent, interferes with platelet signaling. Atopaxar can be used for the research of atherothrombotic disease                       

Information

Atopaxar (E5555, ER-172594-00) is a potent and orally-active inhibitor of Protease-activated receptor-1 (PAR-1). E5555 inhibited the binding of a high-affinity thrombin receptor-activating peptide ([(3)H]haTRAP) to PAR-1 with IC50 of 0.019μM.