Atractylenolide I - Analytical reference, high purity , CAS No.73069-13-3

Item Number
A304497
Grouped product items
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A304497-10mg
10mg
In stock
$284.90
A304497-50mg
50mg
In stock
$865.90
A304497-250mg
250mg
Available within 4-8 weeks(?)
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$3,894.90

Basic Description

SynonymsAtractylenolide I | 73069-13-3 | AtractylenolideI | Atractylenolide-1 | Atractylenolide 1 | Atractylenolide-I | CHEMBL449520 | (4aS,8aS)-3,8a-dimethyl-5-methylidene-4a,6,7,8-tetrahydro-4H-benzo[f][1]benzofuran-2-one | 8,9-dehydroasterolide | MFCD09037395 | SCHEMBL1898423 | DTX
Specifications & Purityanalytical reference
Biochemical and Physiological MechanismsPhytochemical from Traditional Chinese Medicine herbal preparations. Atractylenolide I is an anti-inflammatory that is reported to inhibit angiogenesis.
Storage TempStore at 2-8°C,Protected from light,Desiccated
Shipped InWet ice
Gradeanalytical reference
Product Description

Atractylenolide I is the major sesquiterpenoid of the rhizome of A. macrocephala and shows a wide spectrum of pharmacological activities such as antiinflammatory, digestion promoting, and antioxidant effects.
Atractylenolide I is a phytochemical that may be used to study its anti-inflammatory and anti-angiogenesis activities. Atractylenolide I may be used and studied as a postitive modulator of GABA-induced chloride currents I(GABA) and as an inhibitor of aromatases. Atractylenolide I may be used as a reference material in assays to detect its presence in plant root extracts and biological milieu such as plasma.

Associated Targets(Human)

ALOX5 Tclin Arachidonate 5-lipoxygenase (6568 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PTGS1 Tclin Cyclooxygenase-1 (9233 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
TP53 Tchem Cellular tumor antigen p53 (48468 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
K562 (73714 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
U-937 (7138 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HepG2 (196354 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Jurkat (10389 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

PC-12 (7051 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Names and Identifiers

IUPAC Name (4aS,8aS)-3,8a-dimethyl-5-methylidene-4a,6,7,8-tetrahydro-4H-benzo[f][1]benzofuran-2-one
INCHI InChI=1S/C15H18O2/c1-9-5-4-6-15(3)8-13-11(7-12(9)15)10(2)14(16)17-13/h8,12H,1,4-7H2,2-3H3/t12-,15+/m0/s1
InChi Key ZTVSGQPHMUYCRS-SWLSCSKDSA-N
Canonical SMILES CC1=C2CC3C(=C)CCCC3(C=C2OC1=O)C
Isomeric SMILES CC1=C2C[C@H]3C(=C)CCC[C@@]3(C=C2OC1=O)C
PubChem CID 5321018
Molecular Weight 230.3

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Certificate of Analysis(COA)

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3 results found

Lot NumberCertificate TypeDateItem
J2115099Certificate of AnalysisAug 09, 2024 A304497
J2115100Certificate of AnalysisAug 09, 2024 A304497
J2115135Certificate of AnalysisAug 09, 2024 A304497

Chemical and Physical Properties

Flash Point(°C)170℃
Boil Point(°C)405.0±44.0 °C
Melt Point(°C)121-123 °C

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