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Protease inhibitors
Aurantiamide acetate - 99%, high purity , CAS No.56121-42-7

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Aurantiamide acetate - 99%, high purity , CAS No.56121-42-7

≥99%

CAS#: 56121-42-7
Formula: C₂₇H₂₈N₂O₄
Molecular Weight: 444.52
PubChem CID: 10026486

Item Number

A651241

Grouped product items
SKU	Size	Availability	Price	Qty
A651241-1mg	1mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$152.90
A651241-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$320.90

View related series

Cathepsin Metabolic Enzyme/Protease

Basic Description

Synonyms	AKOS040760046 \| Tifentai \| Benzenepropanamide, N-[(1S)-1-[(acetyloxy)methyl]-2-phenylethyl]-alpha-(benzoylamino)-, (alphaS)- \| MS-28013 \| SCHEMBL4357298 \| 2Z6NA534YE \| C27H28N2O4 \| Aurantiamide acetate \| Asperglaucide \| HY-N2905 \| N-Benzoylphenylalanylphe
Specifications & Purity	≥99%
Biochemical and Physiological Mechanisms	Aurantiamide acetate (TMC-58A) is a selective and orally active cathepsin inhibitor isolated from Portulaca oleracea L. Aurantiamide acetate has anti-inflammatory activities and can be used for the study of xa0inflammatoryxa0diseases.
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads
Product Description	Aurantiamide acetate (TMC-58A) is a selective and orally active cathepsin inhibitor isolated from Portulaca oleracea L. Aurantiamide acetate has anti-inflammatory activities and can be used for the study of inflammatory diseases In Vitro Aurantiamide acetate inhibits cathepsin L (3.4.22.15) and cathepsin B (3.4.22.1) with IC 50 of 12 μM and 49 μM, respectiveiy. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid IC50& Target:cathepsin L

Associated Targets(Human)

N9 (414 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Associated Targets(non-human)

Hepatitis B virus (7925 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mechanisms of Action

Mechanism of Action	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	References

Names and Identifiers

IUPAC Name	[(2S)-2-[[(2S)-2-benzamido-3-phenylpropanoyl]amino]-3-phenylpropyl] acetate
INCHI	InChI=1S/C27H28N2O4/c1-20(30)33-19-24(17-21-11-5-2-6-12-21)28-27(32)25(18-22-13-7-3-8-14-22)29-26(31)23-15-9-4-10-16-23/h2-16,24-25H,17-19H2,1H3,(H,28,32)(H,29,31)/t24-,25-/m0/s1
InChi Key	VZPAURMDJZOGHU-DQEYMECFSA-N
Canonical SMILES	CC(=O)OCC(CC1=CC=CC=C1)NC(=O)C(CC2=CC=CC=C2)NC(=O)C3=CC=CC=C3
Isomeric SMILES	CC(=O)OC[C@H](CC1=CC=CC=C1)NC(=O)[C@H](CC2=CC=CC=C2)NC(=O)C3=CC=CC=C3
PubChem CID	10026486
Molecular Weight	444.52

Certificates

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Chemical and Physical Properties

Solubility	DMSO : 50 mg/mL (112.48 mM; Need ultrasonic)

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