Determine the necessary mass, volume, or concentration for preparing a solution.
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SKU | Size | Availability | Price | Qty |
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A274652-1mg | 1mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $166.90 |
Potent leukotriene B4 inhibitor. Anti-inflammatory agent.
Synonyms | Avarol | 55303-98-5 | Avrol | KZX416VN2B | CHEMBL459814 | 2-[[(1R,2S,4aS,8aS)-1,2,4a,5-tetramethyl-2,3,4,7,8,8a-hexahydronaphthalen-1-yl]methyl]benzene-1,4-diol | UNII-KZX416VN2B | NSC 306951 | NSC-306951 | 1,4-BENZENEDIOL, 2-(((1R,2S,4AS,8AS)-1,2,3,4,4A,7,8,8A-OCTAHYDRO-1 |
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Specifications & Purity | ≥97% |
Biochemical and Physiological Mechanisms | Potent leukotriene B4 inhibitor (IC 50 = 0.6 μM). Anti-inflammatory agent. Inhibits TNF-α (IC 50 = 1 μM) and NFκB. Inhibits thromboxane B2 release and phospholipase A2 activity (IC 50 values are 1.4 and 158 μM respectively). |
Storage Temp | Protected from light,Store at -20°C,Desiccated |
Shipped In | Ice chest + Ice pads |
Note | Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details. |
Product Description | Store at -20°C. It is important to note that this product is reported to be light sensitive. Store In the Dark. Store under desiccating conditions. |
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IUPAC Name | 2-[[(1R,2S,4aS,8aS)-1,2,4a,5-tetramethyl-2,3,4,7,8,8a-hexahydronaphthalen-1-yl]methyl]benzene-1,4-diol |
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INCHI | InChI=1S/C21H30O2/c1-14-6-5-7-19-20(14,3)11-10-15(2)21(19,4)13-16-12-17(22)8-9-18(16)23/h6,8-9,12,15,19,22-23H,5,7,10-11,13H2,1-4H3/t15-,19+,20+,21+/m0/s1 |
InChi Key | JSPUCPNQXKTYRO-LWILDLIXSA-N |
Canonical SMILES | CC1CCC2(C(C1(C)CC3=C(C=CC(=C3)O)O)CCC=C2C)C |
Isomeric SMILES | C[C@H]1CC[C@]2([C@H]([C@]1(C)CC3=C(C=CC(=C3)O)O)CCC=C2C)C |
PubChem CID | 72185 |
Molecular Weight | 314.46 |
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Solubility | Soluble in ethanol and DMSO |
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Sensitivity | light sensitive |