Determine the necessary mass, volume, or concentration for preparing a solution.
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SKU | Size | Availability | Price | Qty |
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A341885-1mg | 1mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $366.90 | |
A341885-500μg | 500μg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $192.90 |
a potent group IVA cPLA2 inhibitor
Synonyms | 873079-69-7 | AX-048 | AX 048 | Butanoic acid, 4-((1,2-dioxohexadecyl)amino)-, ethyl ester | UNII-8782Z45DLV | 8782Z45DLV | Butanoic acid, 4-[(1,2-dioxohexadecyl)amino]-, ethyl ester | ethyl 4-(2-oxohexadecanoylamino)butanoate | ethyl 4-(2-oxohexadecanamido)butanoate | CHE |
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Storage Temp | Store at -20°C |
Shipped In | Ice chest + Ice pads |
Product Description | AX 048, ethyl 4-[(2-oxohexadecanoyl)amino]butanoate, is a PLA|2|(Phospholipase A|2|) and PGE|2|(Prostaglandin E|2|) inhibitor. PLAs are known to play a role in various cellular processes such as host defense, phospholipid digestion and metabolism, and signal transduction. This compound also contains a specific affinity for group IVA cPLA|2|which moderates antihyperalgesia effects. |
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IUPAC Name | ethyl 4-(2-oxohexadecanoylamino)butanoate |
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INCHI | InChI=1S/C22H41NO4/c1-3-5-6-7-8-9-10-11-12-13-14-15-17-20(24)22(26)23-19-16-18-21(25)27-4-2/h3-19H2,1-2H3,(H,23,26) |
InChi Key | FMFKQXKYWWJNJS-UHFFFAOYSA-N |
Canonical SMILES | CCCCCCCCCCCCCCC(=O)C(=O)NCCCC(=O)OCC |
Isomeric SMILES | CCCCCCCCCCCCCCC(=O)C(=O)NCCCC(=O)OCC |
PubChem CID | 15950454 |
Molecular Weight | 383.57 |
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Solubility | Soluble in ethanol (~5 mg/ml), DMSO (~2 mg/ml), and DMF (~10 mg/ml). |
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