AX 048 , CAS No.873079-69-7

Item Number
A341885
Grouped product items
SKUSizeAvailabilityPrice Qty
A341885-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$366.90
A341885-500μg
500μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$192.90

a potent group IVA cPLA2 inhibitor

Basic Description

Synonyms873079-69-7 | AX-048 | AX 048 | Butanoic acid, 4-((1,2-dioxohexadecyl)amino)-, ethyl ester | UNII-8782Z45DLV | 8782Z45DLV | Butanoic acid, 4-[(1,2-dioxohexadecyl)amino]-, ethyl ester | ethyl 4-(2-oxohexadecanoylamino)butanoate | ethyl 4-(2-oxohexadecanamido)butanoate | CHE
Storage TempStore at -20°C
Shipped InIce chest + Ice pads
Product Description

AX 048, ethyl 4-[(2-oxohexadecanoyl)amino]butanoate, is a PLA|2|(Phospholipase A|2|) and PGE|2|(Prostaglandin E|2|) inhibitor. PLAs are known to play a role in various cellular processes such as host defense, phospholipid digestion and metabolism, and signal transduction. This compound also contains a specific affinity for group IVA cPLA|2|which moderates antihyperalgesia effects.

Associated Targets(Human)

PLA2G4A Tchem Cytosolic phospholipase A2 (785 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PLA2G6 Tchem Calcium-independent phospholipase A2 (359 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

RAW264.7 (28094 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Names and Identifiers

IUPAC Name ethyl 4-(2-oxohexadecanoylamino)butanoate
INCHI InChI=1S/C22H41NO4/c1-3-5-6-7-8-9-10-11-12-13-14-15-17-20(24)22(26)23-19-16-18-21(25)27-4-2/h3-19H2,1-2H3,(H,23,26)
InChi Key FMFKQXKYWWJNJS-UHFFFAOYSA-N
Canonical SMILES CCCCCCCCCCCCCCC(=O)C(=O)NCCCC(=O)OCC
Isomeric SMILES CCCCCCCCCCCCCCC(=O)C(=O)NCCCC(=O)OCC
PubChem CID 15950454
Molecular Weight 383.57

Certificates

Certificate of Analysis(COA)

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Chemical and Physical Properties

SolubilitySoluble in ethanol (~5 mg/ml), DMSO (~2 mg/ml), and DMF (~10 mg/ml).

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Solution Calculators