Grouped product items

SKU

Size

Availability

Price

Qty

A647890-1mg

1mg

Available within 8-12 weeks(?)

$357.90

A647890-5mg

5mg

Available within 8-12 weeks(?)

$750.90

Basic Description

Synonyms	Q3277926 \| Ayanin \| DTXSID20205833 \| NSC691652 \| NSC-691652 \| UNII-YA465UF3LK \| MS-25275 \| YA465UF3LK \| QUERCETIN 3,7,4'-TRIMETHYL ETHER \| 3,7,4'-trimethylquercetin \| BDBM50064888 \| AKOS040760283 \| 4H-Benzopyran-4-one, 5-hydroxy-2-(3-hydroxy-4methoxypheny
Specifications & Purity	≥98%
Biochemical and Physiological Mechanisms	Ayanin is a bioflavonoid isolated from Psychotria serpens . Ayanin is a non-selective phosphodiesterase 1-4 inhibitor and can be used for the study of respiratory disease,such as allergic asthma et al.
Storage Temp	Protected from light,Store at -80°C
Shipped In	Ice chest + Ice pads
Product Description	Ayanin is a bioflavonoid isolated from Psychotria serpens . Ayanin is a non-selective phosphodiesterase 1-4 inhibitor and can be used for the study of respiratory disease,such as allergic asthma et al In Vitro Ayanin inhibits interleukin (IL)-4 production from purified basophils with an IC 50 value of 2.2 μM. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid IC50& Target:PDE2A PDE4

Associated Targets(Human)

ABCG2 Tchem ATP-binding cassette sub-family G member 2 (2 Activities)

Discover Target: ABCG2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

F2 Tclin Thrombin (11687 Activities)

Discover Target: F2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

A498 (42825 Activities)

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ACHN (49357 Activities)

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CAKI-1 (44928 Activities)

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CCRF-CEM (65223 Activities)

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COLO 205 (50209 Activities)

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DU-145 (51482 Activities)

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HL-60 (67320 Activities)

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HT-29 (80576 Activities)

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K562 (73714 Activities)

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KM12 (47707 Activities)

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M14 (47487 Activities)

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MCF7 (126967 Activities)

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MOLT-4 (49676 Activities)

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Panel NCI-60 (60 carcinoma cell lines) (1088 Activities)

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OVCAR-3 (48710 Activities)

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OVCAR-4 (44535 Activities)

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OVCAR-5 (45555 Activities)

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OVCAR-8 (47708 Activities)

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PC-3 (62116 Activities)

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RPMI-8226 (44974 Activities)

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RXF 393 (41971 Activities)

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SF-295 (48000 Activities)

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SK-MEL-2 (46422 Activities)

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SK-MEL-28 (48833 Activities)

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SK-MEL-5 (47095 Activities)

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SK-OV-3 (52876 Activities)

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SN12C (47755 Activities)

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SNB-19 (46794 Activities)

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TK-10 (45540 Activities)

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U-251 (51189 Activities)

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UACC-257 (46019 Activities)

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UACC-62 (47335 Activities)

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UO-31 (46270 Activities)

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786-0 (47912 Activities)

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A549 (127892 Activities)

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NCI/ADR-RES (33767 Activities)

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T47D (39041 Activities)

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EKVX (44102 Activities)

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NCI-H157 (619 Activities)

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NCI-H322M (45589 Activities)

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HCC 2998 (41480 Activities)

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HCT-116 (91556 Activities)

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Hs-578T (29457 Activities)

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NCI-H460 (60772 Activities)

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A2780 (11979 Activities)

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SF-268 (49410 Activities)

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IGROV-1 (47897 Activities)

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KB (17409 Activities)

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LOX IMVI (44321 Activities)

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Associated Targets(non-human)

Abcc1 Multidrug resistance-associated protein 1 (42 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Abcb1b P-glycoprotein 1 (174 Activities)

Discover Target: Abcb1b

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Escherichia coli (133304 Activities)

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Bacillus subtilis (32866 Activities)

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rhinovirus A2 (409 Activities)

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Respiratory syncytial virus (3434 Activities)

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3T3-L1 (3664 Activities)

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TUBB2B Tubulin (2175 Activities)

Discover Target: TUBB2B

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B16-F0 (142 Activities)

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Mechanisms of Action

Mechanism of Action	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	References

Names and Identifiers

IUPAC Name	5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-3,7-dimethoxychromen-4-one
INCHI	InChI=1S/C18H16O7/c1-22-10-7-12(20)15-14(8-10)25-17(18(24-3)16(15)21)9-4-5-13(23-2)11(19)6-9/h4-8,19-20H,1-3H3
InChi Key	KPCRYSMUMBNTCK-UHFFFAOYSA-N
Canonical SMILES	COC1=C(C=C(C=C1)C2=C(C(=O)C3=C(C=C(C=C3O2)OC)O)OC)O
Isomeric SMILES	COC1=C(C=C(C=C1)C2=C(C(=O)C3=C(C=C(C=C3O2)OC)O)OC)O
Alternate CAS	572-32-7
PubChem CID	5280682
NSC Number	691652
MeSH Entry Terms	5,3'-dihydroxy-3,7,4'-trimethoxyflavone;ayanin
Molecular Weight	344.32

Certificates

Certificate of Analysis(COA)

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Chemical and Physical Properties

Solubility	DMSO : 250 mg/mL (726.07 mM; Need ultrasonic)

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Ayanin - 98%, high purity , CAS No.572-32-7

Basic Description

Associated Targets(Human)

Associated Targets(non-human)

Mechanisms of Action

Names and Identifiers

Certificates

Certificate of Analysis(COA)

Chemical and Physical Properties

Related Documents

Solution Calculators

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SKU	Size	Availability	Price	Qty
A647890-1mg	1mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$357.90
A647890-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$750.90