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AZ2429 , CAS No.A607839, Agonist of PAR2

Item Number

A607839

Grouped product items
SKU	Size	Availability	Price	Qty
A607839-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$1,000.90
A607839-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$2,000.90

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Basic Description

F2RL1 Tchem Proteinase-activated receptor 2 (0 Activities)

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

IUPAC Name	(1S)-4-[(2S)-2-[(1-benzyl-1H-1,2,3-triazol-4-yl)formamido]-3-cyclohexylpropanamido]-N-methyl-1,2,3,4-tetrahydronaphthalene-1-carboxamide
INCHI	InChI=1S/C31H38N6O3/c1-32-29(38)25-16-17-26(24-15-9-8-14-23(24)25)33-30(39)27(18-21-10-4-2-5-11-21)34-31(40)28-20-37(36-35-28)19-22-12-6-3-7-13-22/h3,6-9,12-15,20-21,25-27H,2,4-5,10-11,16-19H2,1H3,(H,32,38)(H,33,39)(H,34,40)/t25-,26?,27-/m0/s1
InChi Key	SSFQUKJKELJMIP-LLOGBAKRSA-N
Canonical SMILES	CNC(=O)[C@H]1CCC(NC(=O)[C@H](CC2CCCCC2)NC(=O)C3=CN(CC4=CC=CC=C4)N=N3)C5=C1C=CC=C5

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1. Kennedy AJ, Sundström L, Geschwindner S, Poon EKY, Jiang Y, Chen R, Cooke R, Johnstone S, Madin A, Lim J et al.. (2020) Protease-activated receptor-2 ligands reveal orthosteric and allosteric mechanisms of receptor inhibition.. Commun Biol, 3 (1): (782). [PMID:33335291] [10.1021/op500134e]

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