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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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A412343-1mg | 1mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $25.90 | |
A412343-5mg | 5mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $76.90 | |
A412343-10mg | 10mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $99.90 | |
A412343-25mg | 25mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $179.90 | |
A412343-50mg | 50mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $269.90 | |
A412343-100mg | 100mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $429.90 |
Specifications & Purity | ≥98% |
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Biochemical and Physiological Mechanisms | AZ9482 is a potent and selective inhibitor of PARP featuring an amide linkage to a 2-piperazinyl-3-cyano-pyridine. AZ9482 exhibits very potent centrosome declustering activity with EC50 of < 18 nM in HeLa cells. |
Storage Temp | Store at -20°C |
Shipped In | Ice chest + Ice pads |
Product Description | Information AZ9482 is a potent and selective inhibitor of PARP featuring an amide linkage to a 2-piperazinyl-3-cyano-pyridine. AZ9482 exhibits very potent centrosome declustering activity with EC50 of < 18 nM in HeLa cells. |
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Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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IUPAC Name | 2-[4-[3-[(4-oxo-3H-phthalazin-1-yl)methyl]benzoyl]piperazin-1-yl]pyridine-3-carbonitrile |
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INCHI | InChI=1S/C26H22N6O2/c27-17-20-7-4-10-28-24(20)31-11-13-32(14-12-31)26(34)19-6-3-5-18(15-19)16-23-21-8-1-2-9-22(21)25(33)30-29-23/h1-10,15H,11-14,16H2,(H,30,33) |
InChi Key | ZDDPBFWHZOJFHF-UHFFFAOYSA-N |
Canonical SMILES | C1CN(CCN1C2=C(C=CC=N2)C#N)C(=O)C3=CC=CC(=C3)CC4=NNC(=O)C5=CC=CC=C54 |
Isomeric SMILES | C1CN(CCN1C2=C(C=CC=N2)C#N)C(=O)C3=CC=CC(=C3)CC4=NNC(=O)C5=CC=CC=C54 |
PubChem CID | 92045137 |
Molecular Weight | 450.5 |
Enter Lot Number to search for COA:
Find and download the COA for your product by matching the lot number on the packaging.
Lot Number | Certificate Type | Date | Item |
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A2404517 | Certificate of Analysis | Dec 13, 2023 | A412343 |
A2404520 | Certificate of Analysis | Dec 13, 2023 | A412343 |
A2404521 | Certificate of Analysis | Dec 13, 2023 | A412343 |
A2404862 | Certificate of Analysis | Dec 13, 2023 | A412343 |
A2404863 | Certificate of Analysis | Dec 13, 2023 | A412343 |
A2404864 | Certificate of Analysis | Dec 13, 2023 | A412343 |
A2404865 | Certificate of Analysis | Dec 13, 2023 | A412343 |
A2404866 | Certificate of Analysis | Dec 13, 2023 | A412343 |
A2404867 | Certificate of Analysis | Dec 13, 2023 | A412343 |