Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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A288638-5mg | 5mg | In stock | $81.90 | |
A288638-10mg | 10mg | In stock | $146.90 | |
A288638-25mg | 25mg | In stock | $330.90 | |
A288638-50mg | 50mg | In stock | $597.90 | |
A288638-100mg | 100mg | In stock | $924.90 |
Potent and selective CCR4 antagonist
Specifications & Purity | Moligand™, ≥98%(HPLC) |
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Biochemical and Physiological Mechanisms | AZD-2098 is an orally active, potent and selective CCR4 antagonist (pIC50 = 7.8/8.0/8.0/7.6 against CCL22 binding to human/mouse/rat/dog CCR4; inactive toward CXCR1/2 & CCR1/2b/5/7/8 at 10 μM) with little or no activity toward a panel of ∼120 receptors/en |
Storage Temp | Store at -20°C |
Shipped In | Ice chest + Ice pads |
Grade | Moligand™ |
Action Type | ANTAGONIST |
Mechanism of action | Antagonist of CCR4 |
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IUPAC Name | 2,3-dichloro-N-(3-methoxypyrazin-2-yl)benzenesulfonamide |
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INCHI | InChI=1S/C11H9Cl2N3O3S/c1-19-11-10(14-5-6-15-11)16-20(17,18)8-4-2-3-7(12)9(8)13/h2-6H,1H3,(H,14,16) |
InChi Key | FLSMVCMSUNISFK-UHFFFAOYSA-N |
Canonical SMILES | COC1=NC=CN=C1NS(=O)(=O)C2=C(C(=CC=C2)Cl)Cl |
Isomeric SMILES | COC1=NC=CN=C1NS(=O)(=O)C2=C(C(=CC=C2)Cl)Cl |
PubChem CID | 10308720 |
Molecular Weight | 334.18 |
Enter Lot Number to search for COA:
Find and download the COA for your product by matching the lot number on the packaging.
Lot Number | Certificate Type | Date | Item |
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C2209208 | Certificate of Analysis | Feb 20, 2022 | A288638 |
C2209252 | Certificate of Analysis | Feb 20, 2022 | A288638 |
C2209256 | Certificate of Analysis | Feb 20, 2022 | A288638 |
C2209306 | Certificate of Analysis | Feb 20, 2022 | A288638 |
C2209327 | Certificate of Analysis | Feb 20, 2022 | A288638 |
Solubility | Solvent:DMSO, Max Conc. mg/mL: 33.42, Max Conc. mM: 100; Solvent:ethanol, Max Conc. mg/mL: 3.34, Max Conc. mM: 10 |
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Pictogram(s) | GHS08, GHS07 |
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Signal | Warning |
Hazard Statements | H341:Suspected of causing genetic defects H373:Causes damage to organs through prolonged or repeated exposure H302:Harmful if swallowed |
Precautionary Statements | P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P260:Do not breathe dust/fume/gas/mist/vapors/spray. P281:Use personal protective equipment as required. P270:Do not eat, drink or smoke when using this product. P330:Rinse mouth. P203:Obtain, read and follow all safety instructions before use. P301+P317:IF SWALLOWED: Get medical help. P318:if exposed or concerned, get medical advice. P319:Get medical help if you feel unwell. |