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AZD 2098 - ≥98%(HPLC), high purity , CAS No.566203-88-1, Antagonist of CCR4
Potent and selective CCR4 antagonist
Basic Description Specifications & Purity Moligand™, ≥98%(HPLC) Biochemical and Physiological Mechanisms AZD-2098 is an orally active, potent and selective CCR4 antagonist (pIC50 = 7.8/8.0/8.0/7.6 against CCL22 binding to human/mouse/rat/dog CCR4; inactive toward CXCR1/2 & CCR1/2b/5/7/8 at 10 μM) with little or no activity toward a panel of ∼120 receptors/en Storage Temp Store at -20°C Shipped In Ice chest + Ice pads Grade Moligand™ Action Type ANTAGONIST Mechanism of action Antagonist of CCR4
Associated Targets(Human) Associated Targets(non-human) Mechanisms of Action Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References
Names and Identifiers IUPAC Name 2,3-dichloro-N-(3-methoxypyrazin-2-yl)benzenesulfonamide INCHI InChI=1S/C11H9Cl2N3O3S/c1-19-11-10(14-5-6-15-11)16-20(17,18)8-4-2-3-7(12)9(8)13/h2-6H,1H3,(H,14,16) InChi Key FLSMVCMSUNISFK-UHFFFAOYSA-N Canonical SMILES COC1=NC=CN=C1NS(=O)(=O)C2=C(C(=CC=C2)Cl)Cl Isomeric SMILES COC1=NC=CN=C1NS(=O)(=O)C2=C(C(=CC=C2)Cl)Cl PubChem CID 10308720 Molecular Weight 334.18
Chemical and Physical Properties Solubility Solvent:DMSO, Max Conc. mg/mL: 33.42, Max Conc. mM: 100; Solvent:ethanol, Max Conc. mg/mL: 3.34, Max Conc. mM: 10
Safety and Hazards(GHS) Pictogram(s) GHS08 , GHS07 Signal Warning Hazard Statements H341: Suspected of causing genetic defects
H373: Causes damage to organs through prolonged or repeated exposure
H302: Harmful if swallowed
Precautionary Statements P405: Store locked up.
P501: Dispose of contents/container to ...
P264: Wash hands [and …] thoroughly after handling.
P260: Do not breathe dust/fume/gas/mist/vapors/spray.
P281: Use personal protective equipment as required.
P270: Do not eat, drink or smoke when using this product.
P330: Rinse mouth.
P203: Obtain, read and follow all safety instructions before use.
P301+P317: IF SWALLOWED: Get medical help.
P318: if exposed or concerned, get medical advice.
P319: Get medical help if you feel unwell.
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