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AZD3293 (Lanabecestat) - 10mM in DMSO, high purity , CAS No.1383982-64-6

Item Number

A421451

Grouped product items
SKU	Size	Availability	Price	Qty
A421451-1ml	1ml	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$241.90

blood-brain barrier (BBB) penetrating, specific BACE-1 inhibitor

Basic Description

Synonyms	(1r,4r)-4-methoxy-5''-methyl-6'-(5-(prop-1-yn-1-yl)pyridin-3-yl)-3'H-dispiro[cyclohexane-1,2'-indene-1',2''-imidazol]-4''-amine \| Lanabecestat(AZD3293,LY-3314814) \| AZD 3293 \| US8865911, 114 \| HY-100740 \| n-(2-chloroethyl)-pyrrolidine.hydrochloride \| Lana
Specifications & Purity	Moligand™, 10mM in DMSO
Storage Temp	Store at -80°C
Shipped In	Ice chest + Ice pads

ALogP	3

BACE1 Tchem Beta-secretase 1 (3 Activities)

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

INCHI	InChI=1S/C26H28N4O/c1-4-5-18-12-21(16-28-15-18)19-6-7-20-14-25(10-8-22(31-3)9-11-25)26(23(20)13-19)29-17(2)24(27)30-26/h6-7,12-13,15-16,22H,8-11,14H2,1-3H3,(H2,27,30)/t22?,25?,26-/m0/s1
InChi Key	WKDNQONLGXOZRG-BOPKNSRXSA-N
Canonical SMILES	CC#CC1=CC(=CN=C1)C2=CC3=C(CC4(C35N=C(C(=N5)N)C)CCC(CC4)OC)C=C2
Isomeric SMILES	CC#CC1=CC(=CN=C1)C2=CC3=C(CC4([C@]35N=C(C(=N5)N)C)CCC(CC4)OC)C=C2
Alternate CAS	1383984-21-1,1383982-64-6
PubChem CID	67979346
MeSH Entry Terms	4-methoxy-5'-methyl-6'-(5-(prop-1-yn-1-yl)pyridin-3-yl)-3'H-dispiro(cyclohexane-1,2'-inden-1',2'-imidazol)-4'-amine;AZD3293;lanabecestat
Molecular Weight	412.5

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