AZD3839 - 98%, high purity , CAS No.1227163-84-9, Inhibitor of beta-secretase 1

Item Number

A275977

• Synonyms: 1227163-84-9|AZD3839|AZD-3839|AZD3839 free base|(S)-1-(2-(difluoromethyl)pyridin-4-yl)-4-fluoro-1-(3-(pyrimidin-5-yl)phenyl)-1H-isoindol-3-amine|AZD3839 (free base)|(1S)-1-(2-(Difluoromethyl)pyridin-4-yl)-4-fluoro-1-(3-(pyrimidin-5-yl)phenyl)-1H-isoindol-
• Specifications & Purity: Moligand™, ≥98%
• Biochemical and Physiological Mechanisms: Potent and selective\xa0BACE-1\xa0inhibitor (K i = 26.1 nM), about 14-fold selectivity over BACE-2 (K i = 372 nM). Decreases Aβ40 levels (IC 50 = 4.8 nM) and decreases formation of sAPPβ (IC 50 = 16.7 nM).
• Storage Temp: Store at -20°C
• Shipped In: Ice chest + Ice pads
• Grade: Moligand™
• Action Type: INHIBITOR
• Mechanism of action: Inhibitor of beta-secretase 1
• Note: Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Product Description

Shipped at 4°C. Store at -20°C.